CAS 3922-61-0

1,1'-[(1R)-1-(3-Hydroxy-7-méthyl-3-oxyde-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-éthanediyl] dihexadécanoate

Description :

1,1'-[(1R)-1-(3-Hydroxy-7-méthyl-3-oxyde-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-éthanediyl] dihexadécanoate, avec le numéro CAS 3922-61-0, est un composé organique complexe caractérisé par ses caractéristiques structurelles uniques, y compris un groupe phosphonate et des groupes d'acides gras à chaîne longue. Cette substance est susceptible d'exhiber des propriétés amphiphiles en raison de la présence de composants à la fois hydrophiles (les groupes phosphonate et hydroxyle) et hydrophobes (les chaînes d'hexadécanoate), ce qui peut faciliter les interactions avec les membranes biologiques et d'autres environnements lipidiques. Ses applications potentielles peuvent inclure une utilisation en tant que tensioactif, émulsifiant ou dans des systèmes de délivrance de médicaments, en particulier dans des formulations ciblant une absorption cellulaire spécifique. La présence du groupe phosphonate suggère qu'il peut également avoir une pertinence biologique, influençant possiblement la signalisation cellulaire ou les voies métaboliques. De plus, la stéréochimie indiquée par la configuration (1R) peut affecter son activité biologique et ses interactions avec d'autres molécules. Dans l'ensemble, ce composé représente une classe de substances similaires aux phospholipides avec une utilité potentielle dans diverses applications biochimiques et pharmaceutiques.

Formule : C₃₉H₇₈NO₈P

InChI : InChI=1S/C39H78NO8P/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-38(41)45-35-37(36-47-49(43,44)46-34-33-40(3)4)48-39(42)32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h37H,5-36H2,1-4H3,(H,43,44)/t37-/m1/s1

Code InChI : InChIKey=SKWDCOTXHWCSGS-DIPNUNPCSA-N

SMILES : [C@@H](OC(CCCCCCCCCCCCCCC)=O)(COC(CCCCCCCCCCCCCCC)=O)COP(OCCN(C)C)(=O)O

Synonymes :

• (2R)-3-(((2-(Dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate
• 1,1′-[(1R)-1-(3-Hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl] dihexadecanoate
• 1,2-Dihexadecanoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine
• 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine
• <span class="text-smallcaps">L</span>-α-Dipalmitoyl-N,N-dimethylphosphatidylethanolamine
• <span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidyl-N,N-dimethylethanolamine
• Hexadecanoic acid, (1R)-1-(3-hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl ester
• Hexadecanoic acid, 1,1′-[(1R)-1-(3-hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl] ester
• Hexadecanoic acid, 1-(3-hydroxy-7-methyl-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl ester, P-oxide, (R)-
• Hexadecanoic acid, 1-(3-hydroxy-7-methyl-3-oxido-2,4-dioxa-7-aza-3-phosphaoct-1-yl)-1,2-ethanediyl ester, (R)-
• Palmitin, 1,2-di-, 2-(dimethylamino)ethyl hydrogen phosphate, <span class="text-smallcaps">L</span>-
• alpha-Dimethyl dipalmitoylphosphatidylethanolamine
• (R)-1-(3-Hydroxy-7-methyl-2,4-dioxa-7-aza-3-phosphaoct-1-yl)ethylene dipalmitate P-oxide

(2R)-3-(((2-(Dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

CAS : 3922-61-0

(2R)-3-(((2-(Dimethylamino)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate

Degré de pureté : 98%

Masse moléculaire : 720.03g/mol

Ref: 54-OR1060696

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine

CAS : 3922-61-0

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine is a liquid crystalline molecule that is used in the synthesis of lipids. It has two hydrophilic heads and one hydrophobic tail, which allows it to be soluble in water. 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine can form bilayers with other molecules due to its transition properties. The transition occurs at temperatures between 43°C and 45°C. This transition is linearly dependent on the temperature increase. When heated to 50°C, this molecule undergoes a second phase transition from a liquid crystalline state to a thermotropic liquid crystalline state. The calorimetry data for this molecule shows that there are no enthalpic or entropic contributions to the entropy change during the phase

Formule : C₃₉H₇₈NO₈P

Degré de pureté : Min. 95%

Masse moléculaire : 720.03 g/mol

Ref: 3D-FD172100

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine

CAS : 3922-61-0

1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine is a reagent that is used in research and development as a building block for chemical synthesis. It is a versatile intermediate that can be used to produce other compounds or scaffolds. This compound has been found to be useful in the production of pharmaceuticals, pesticides, and food additives. It can also be used as a reaction component in the preparation of many fine chemicals. 1,2-Dipalmitoyl-sn-glycero-3-phospho-N,N-dimethylethanolamine has CAS number 392261–0 and can be purchased from Sigma Aldrich Chemical Co., Inc.

Formule : C₃₉H₇₈NO₈P

Masse moléculaire : 720.03 g/mol

Ref: 3D-D-6057

1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE

CAS : 3922-61-0

1,2-Dipalmitoyl-sn-glycero-3-N,N-dimethyl-PE is a derivative of 1,2-dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) with two added methyl groups on its sn-3 moiety, which in aqueous suspensions, reduces the phase transition temperature relative to those of 1,2-DPPE and 1,2-dipalmitoyl-sn-glycero-3-N-methyl-PE (1,2-NMeDPPE). It is utilized in creating liposomes and monolayers for investigating membrane permeability and monolayer viscosity.

Formule : C₃₉H₇₈NO₈P

Couleur et forme : Solid

Masse moléculaire : 720.026

Ref: TM-T85251