CAS 426834-69-7

NS5806

CAS : 426834-69-7

NS5806 activates K+ currents, slows KV4.2/4.3 decay with KChIP2, and boosts KV4.3/KChIP2 peaks (EC50=5.3μM).

Formule : C₁₆H₈Br₂F₆N₆O

Degré de pureté : 97.95%

Couleur et forme : Solid

Masse moléculaire : 574.07

Ref: TM-T16348

NS5806

CAS : 426834-69-7

NS5806

Degré de pureté : ≥95%

Masse moléculaire : 574.07g/mol

Ref: 54-BUP09741

NS 5806

CAS : 426834-69-7

NS 5806 is a calcium-channel blocker that has been shown in clinical studies to be effective in treating hypertension. NS 5806 binds to the L-type calcium channel, which causes a decrease in intracellular calcium levels and results in vasodilation. It also decreases cardiac excitability and contractility, which is beneficial for patients with angina or heart failure. NS 5806 has been shown to be safe and effective for treating hypertension, with no adverse effects on systolic pressure, atrial fibrillation, or left ventricular function. The mechanism of action of NS 5806 may involve structural changes in the neuronal membrane that result from an increase in intracellular calcium levels.
NS 5806 binds to the L-type calcium channels (Cav1.2) on the surface of heart muscle cells and blocks the influx of Ca2+, preventing contraction and prolonging relaxation time during diastole. This allows more blood to fill chambers before they are contracted again by myof

Formule : C₁₆H₈Br₂F₆N₆O

Degré de pureté : Min. 95%

Masse moléculaire : 574.07 g/mol

Ref: 3D-BSA83469