
CAS 433249-94-6
:3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one
CAS :Formule :C17H17NODegré de pureté :98%Masse moléculaire :251.3230TRAF-STOP inhibitor 6877002
CAS :TRAF-STOP inhibitor 6877002Degré de pureté :≥98%Masse moléculaire :251.32g/mol3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one
CAS :Produit contrôléApplications 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one functions as CD40-TRAF6 inhibitors. Inhibition of CD40 signalling pathway seems a better way to ameliorate inflammatory diseases, like the inflammation in models of peritonitis and sepsis.
References Zarzycka, B., et al.: J. Chem. Inf. Model., 55, 294 (2015);Formule :C17H17NOCouleur et forme :NeatMasse moléculaire :251.32TRAF-STOP inhibitor 6877002
CAS :TRAF-STOP inhibitor 6877002 is a molecule inhibitor that inhibits the activity of signalling molecules in chronic inflammation, atherosclerosis, and cardiac hypertrophy. TRAF-STOP inhibitor 6877002 is an inhibitor group that blocks the signalling pathways involved in cardiac function. It has been shown to inhibit cardiac hypertrophy by inhibiting the signaling pathways mediated by TNF-α, IL-1β, and IL-6. This drug also reduces systolic dysfunction in heart failure patients with reduced ejection fraction by suppressing myocardial fibrosis.
Formule :C17H17NODegré de pureté :Min. 95%Masse moléculaire :251.32 g/molTRAF-STOP inhibitor 6877002
CAS :TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.Formule :C17H17NODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :251.32




