CAS 468741-42-6

BMS-554417

CAS : 468741-42-6

BMS-554417 inhibits IGF-IR/insulin receptors, curbing cell proliferation and tumor growth, with IC50 values of 120 nm–>8.5 μmol/L.

Formule : C₂₈H₃₀ClN₇O₂

Couleur et forme : Solid

Masse moléculaire : 532.04

Ref: TM-T69221

BMS-554417

CAS : 468741-42-6

BMS-554417 is a peptide inhibitor that binds to the receptor of the protein tyrosine phosphatase 1B (PTP1B). BMS-554417 is a potent inhibitor of PTP1B, with IC50 values in the low nanomolar range. The binding site on PTP1B has been mapped to a region between residues T478 and V480. BMS-554417 has been shown to activate the G protein pathway in human neutrophils, suggesting that it may have therapeutic potential for disorders such as chronic inflammation and atherosclerosis.

Formule : C₂₈H₃₀ClN₇O₂

Degré de pureté : Min. 95%

Masse moléculaire : 532 g/mol

Ref: 3D-TTA74142