CAS 50-55-5
:(-)-Reserpine
Description :
(-)-Reserpine est un alcaloïde indole dérivé de la plante Rauwolfia serpentina, couramment connu pour son utilisation en médecine traditionnelle et comme agent antihypertenseur. Il se caractérise par sa structure complexe, qui comprend un noyau tétracyclique et un groupe méthoxy. Le composé présente un centre chiral, ce qui entraîne sa désignation en tant que "(-)-Reserpine," indiquant sa forme énantiomérique spécifique. (-)-Reserpine fonctionne principalement comme un antagoniste des monoamines, influençant les niveaux de neurotransmetteurs dans le cerveau, en particulier en inhibant la recapture de la noradrénaline et de la sérotonine. Ce mécanisme contribue à ses effets sédatifs et antihypertenseurs. La substance est généralement administrée sous forme de sel, comme le chlorhydrate de réserpine, et est connue pour sa demi-vie relativement longue. En plus de ses applications thérapeutiques, (-)-Reserpine a été étudié pour ses effets potentiels sur les troubles de la santé mentale, bien que son utilisation ait diminué en raison du développement de nouveaux médicaments avec moins d'effets secondaires. Les considérations de sécurité incluent des effets indésirables potentiels tels que la sédation, des troubles gastro-intestinaux et des impacts cardiovasculaires.
Formule :C33H40N2O9
InChI :InChI=1/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/p+1/t18-,22+,24-,27+,28+,31+/m1/s1
Code InChI :InChIKey=QEVHRUUCFGRFIF-MDEJGZGSSA-N
SMILES :C(OC)(=O)[C@H]1[C@]2(C[C@@]3(C4=C(C=5C(N4)=CC(OC)=CC5)CCN3C[C@]2(C[C@@H](OC(=O)C6=CC(OC)=C(OC)C(OC)=C6)[C@@H]1OC)[H])[H])[H]
Synonymes :- (3Beta,16Beta,17Alpha,18Alpha,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
- (3Beta,16Beta,17Alpha,18Beta,20Alpha)-11,17-Dimethoxy-16-(Methoxycarbonyl)-18-[(3,4,5-Trimethoxybenzoyl)Oxy]Yohimban-4-Ium
- 11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylic acid methyl ester
- 3,4,5-Trimethoxybenzoyl methyl reserpate
- 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)
- 3β,20α-Yohimban-16β-carboxylic acid, 18β-hydroxy-11,17α-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate
- Anquil
- Apoplon
- Banasil
- Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.
- Bioserpine
- Carpacil
- Crystoserpine
- Deserpine
- Elserpine
- Ent 50146
- Eserpine
- Eskaserp
- Hiposerpil
- Kitine
- Lemiserp
- Loweserp
- Mayserpine
- Methyl reserpate 3,4,5-trimethoxybenzoate (ester)
- Nsc 237659
- Nsc 59272
- Quiescin
- Rau-sed
- Raucap
- Raulen
- Raunervil
- Raupasil
- Raurine
- Rausedil
- Rausedyl
- Rausingle
- Rauwasedin
- Resercaps
- Resercen
- Reserlor
- Reserpamed
- Reserpex
- Reserpic acid methyl ester 3,4,5-trimethoxybenzoate (ester)
- Reserpil
- Reserpin
- Reserpina
- Reserpine Crystalline
- Reserpine base
- Reserpine,98%
- Reserpoid
- Resine
- Resperine
- Respital
- Restran
- Riserpa
- Rivasin
- Roxinoid
- Sandril
- Sedaraupin
- Sedserp
- Serfin
- Serolfia
- Serp-AFD
- Serpaloid
- Serpanray
- Serpasil
- Serpasil Serpasol
- Serpasil premix
- Serpasol
- Serpate
- Serpen
- Serpentina
- Serpicon
- Serpiloid
- Serpine
- Serpine (pharmaceutical)
- Serpipur
- Sertabs
- Sertina
- T-Serp
- Temposerpine
- Triserpin
- Vio-Serpine
- Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3β,16β,17α,18β,20α)-
- NCI-C50157
- Anguil
- rauwita
- Ascoserpina
- imethoxy-,methylester,3,4,5-trimethoxybenzoate(ester)
- diutensen-r
- 3,20-YohiMban-16-carboxylic acid
- hydroserp
- gamma-Serpine
- serpasilpremix
- Carrserp
- reserpene
- Austrapine
- serpalan
- Rausan
- Helfoserpin
- rcrawastenumberu200
- Hypersine
- chloroserpin-250
- serpazol
- Reserpine (base and/or unspecified salts)
- demi-regroton
- Neoserp
- reser-ar
- Interpina
- RESERPINE(RG)
- YohiMban-16-carboxylicacid, 11,17-diMethoxy-18-[(3,4,5-triMethoxybenzoyl)oxy]-, Methyl ester, (3b,16b,17a,18b,20a)-
- (3β,16β,17α,18β,20α)-
- Purserpine
- Alserin
- 11,17-dimethoxy-18-((3,4,5-trimethoxybenzoyl)oxy)-yohimban-16-carboxylicaci
- Rautrin
- salutensin
- rolserp
- trichlortensin
- Escaspere
- Alkarau
- Rauserpin-Alk
- oxy-methylester3,4,5-trimethoxybenzoate(ester)
- hydromox-r
- residine
- RESERPINE,USP
- chloroserp-500
- serpyrit
- Raugal
- chloroserpine-500
- reserp
- RESERPINE
- Enipresser
- RESERPINE,REAGENT
- Reserpine (200 mg)
- 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylicaci
- Raudixoid
- Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(3,4,5-trimethoxybenzoyl)oxy-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-
- serpresan
- Rausedan
- serpone
- Reserpine Standard for LC-MS
- Benazyl
- rezide
- serpasil-apresoline
- reserpidefe
- component of Butiserpazide
- serathide
- METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER
- METHYL RESERPATE
- R-e-s
- rivased
- Methyl reserpate 3,4,5-trimethyloxybenzoic acid
- hydrosine25
- reserfia
- klimanosid
- resedril
- serplexk
- Rauserpine
- Maviserpin
- Rauloydin
- renese-r
- diupres250
- rese-lar
- Carditivo
- serpivite
- Eskaserpine
- serpogen
- reserutin
- hydroserpineplus
- Broserpine
- Rauvlid
- banisil
- l-Carpserp
- mallopress
- ReserpineC33H40N209
- Eberpine
- hydro-reserpine-25
- serfolia
- chloroserp-250
- Eberspine
- metatensin#2
- tri-hydroserpine
- methylreserpate3,4,5-trimethoxybenzoicacid
- serpazil
- hydrochloride#2
- hydrochloride#1
- hydro-fluserpine#1
- recipin
- salutensin-demi
- Rauwipur
- serpazide
- resersana
- regroton
- hydropres50
- salazide-demi
- component of Regroton
- Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha)-
- component of Renese R
- Rauserpol
- ReserpinePuriss
- reserpanca
- Key-serpine
- Reserpine bp
- Reserpine Vetec(TM) reagent grade
- diurese-r
- diupres500
- ser-a-gen
- reserpal
- ent50146
- Raupoid
- Reserpine, froM Rauvolfia
- Raunorine
- resomine
- (3beta,16beta,17alpha,18beta,20alpha)-methyleste
- hydropine
- hydroserpine#1
- metatensin#4
- RESERPINE BP/USP
- ,methylester,(3beta,16beta,17alpha,18beta,20alpha)-
- hydro-reserpine-50
- Raudiford
- resperin
- Idsoserp
- Rawilid
- Hiserpia
- hiposepil
- YohiMban-16-carboxylic acid
- Neo-antitensol
- RESERPINE, CRYSTALLIZED
- usafcb-27
- serpatone
- serpedin
- hydropres25
- salupres
- Rauwilid
- resiatric
- Neoserfin
- esidrix#2
- Reserbal
- Mephaserpin
- Reserpine,99%
- Hypersil
- reserpur
- hydroserpalan
- H 520
- Resedrex
- resaltex
- resocalm
- rezerpin
- Raumorine
- gilucard
- seominal
- 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-hydroxy-11,17alpha-dimethoxy-methyl ester 3,4,5-trimethoxybenzoate (ester)
- serpoid
- RESERPINE extrapure
- Rauwoleaf
- Reserjen
- (3β,16β,17α,18β,20α)-11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylicacidmethylester
- Voir plus de synonymes
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Reserpine
CAS :Formule :C33H40N2O9Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :608.69Reserpine, 99%
CAS :<p>Inhibits vesicular uptake of catecholamines and serotoninReserpine is an antipsychotic and antihypertensive drug used to treat the hypertension, strokes, heart attacks and kidney problems. It is used to treat the symptoms of dyskinesia in patients who are affected by huntington’s disease. It is wide</p>Formule :C33H40N2O9Degré de pureté :99%Couleur et forme :White to cream to yellow, PowderMasse moléculaire :608.69RESERPINE CRS
CAS :<p>RESERPINE CRS</p>Formule :C33H40N2O9Couleur et forme :Crystalline Powder. White. Light Yellow. Small. Crystals. Powder.Masse moléculaire :608.6787Reserpine
CAS :<p>Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi</p>Formule :C33H40N2O9Couleur et forme :White Pale Yellow Crystalline PowderMasse moléculaire :608.27338Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester,(3b,16b,17a,18b,20a)-
CAS :Formule :C33H40N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :608.6787Reserpine
CAS :<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formule :C33H40N2O9Degré de pureté :98.85% - 99.81%Couleur et forme :White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Masse moléculaire :608.68Reserpine
CAS :Formule :C33H40N2O9Degré de pureté :≥ 98.0%Couleur et forme :White to pale yellow or faint brown powderMasse moléculaire :608.69Reserpine
CAS :Natural alkaloidFormule :C33H40N2O9Degré de pureté :≥ 95.0 % (HPLC)Couleur et forme :PowderMasse moléculaire :608.69Reserpine
CAS :Produit contrôlé<p>Applications An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.<br>References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),<br></p>Formule :C33H40N2O9Couleur et forme :Off-WhiteMasse moléculaire :608.68Reserpine - Bio-X ™
CAS :<p>Reserpine is an indole alkaloid that is found in the roots of the Rauwolfia plant. Reserpine has been shown to possess analgesic, anti-inflammatory, sedative, and anti-hypertensive properties. It is mainly used to treat mild to moderate hypertension. Reserpine inhibits the uptake of norepinephrine into storage vesicles by irreversibly blocking the vesicular monoamine transporter thus resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It is used as a pharmacological tool in research on chronic liver diseases.</p>Formule :C33H40N2O9Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :608.68 g/molReserpine
CAS :<p>VMAT monoamine transporter inhibitor; anti-hypertensive; anti-psychotic</p>Formule :C33H40N2O9Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :608.68 g/molReserpine extrapure, 99%
CAS :Formule :C33H40N2O9Degré de pureté :min. 99%Couleur et forme :White to pale yellow to pale beige to pale brown, Crystalline powder, ClearMasse moléculaire :608.69
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