CAS 502632-66-8

PX-866

CAS : 502632-66-8

PX-866

Formule : C₂₉H₃₅NO₈

Degré de pureté : By hplc: 98.35% (Typical Value in Batch COA)

Couleur et forme : orange powder

Masse moléculaire : 525.59g/mol

Ref: 54-BIP1009

PX 866

CAS : 502632-66-8

Potent and irreversible inhibitor of phosphoinositide-3-kinase (PtdIns-3-kinase) with IC50 of 0.1 nM. PX 866 inhibited cell motility and growth of 3D spheroids of glioblastoma, breast, prostate and colon cancer cell lines at low nanomolar concentrations. PX 866 also exhibited anti-tumoral activity in vivo in xenograft models for ovarian and lung cancer.

Formule : C₂₉H₃₅NO₈

Degré de pureté : Min. 98 Area-%

Couleur et forme : Powder

Masse moléculaire : 525.59 g/mol

Ref: 3D-BP162743

Sonolisib

CAS : 502632-66-8

Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)).

Formule : C₂₉H₃₅NO₈

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 525.59

Ref: TM-T16908