![N2-[N-(N-acetylmuramoyl)-L-alanyl]-D-α-glutamine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F299649-n-acetylmuramyl-l-alanyl-d-isoglutamine.webp&w=3840&q=75)
CAS 53678-77-6
:N2-[N-(N-acétylmuramoyl)-L-alanyl]-D-α-glutamine
Description :
N2-[N-(N-acétylmuramoyl)-L-alanyl]-D-α-glutamine, communément appelé un dérivé de peptidoglycane, est un composé qui joue un rôle significatif dans la structure et la fonction de la paroi cellulaire bactérienne. Cette substance se caractérise par sa combinaison unique d'acides aminés et d'un groupe muramyle, qui est essentiel à la stabilité et à l'intégrité des parois cellulaires bactériennes. La présence du groupe N-acétylmuramyle contribue à son activité biologique, en particulier dans les interactions avec le système immunitaire. Le composé présente des propriétés typiques des peptides, y compris la solubilité dans l'eau et la réactivité potentielle avec diverses molécules biologiques. Sa structure lui permet de participer à d'importantes voies biochimiques, en particulier dans le contexte de la croissance bactérienne et de la modulation de la réponse immunitaire. De plus, en raison de sa composition spécifique en acides aminés, il peut présenter des affinités de liaison uniques et des interactions enzymatiques, ce qui en fait un sujet d'intérêt en microbiologie et en pharmacologie. Comprendre ses caractéristiques peut fournir des informations sur la physiologie bactérienne et le développement d'agents antimicrobiens.
Formule :C19H32N4O11
InChI :InChI=1/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19+/m0/s1
Code InChI :InChIKey=MEJOVVKHFORGKW-HOMBLFBHSA-N
SMILES :[C@H]([C@@H](NC(C)=O)C=O)(O[C@@H](C(N[C@H](C(N[C@H](CCC(O)=O)C(N)=O)=O)C)=O)C)[C@@H]([C@@H](CO)O)O
Synonymes :- (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,3R,4R,5S,6R)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name)
- (4R)-4-{[(2S)-2-{[(2R)-2-{[(2R,5S)-3-(acetylamino)-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoyl]amino}propanoyl]amino}-5-amino-5-oxopentanoic acid (non-preferred name)
- 2: PN: WO2009039971 PAGE: 99 claimed protein
- <span class="text-smallcaps">D</smallcap>-α-Glutamine, N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl-
- <span class="text-smallcaps">D</smallcap>-α-Glutamine, N<sup>2</sup>-[N-(N-acetylmuramoyl)-<smallcap>L</span>-alanyl]-
- Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine
- Acetylmuramyl-L-alanyl-D-isoglutamine
- Acetylmuramyl-alanyl-isoglutamine
- Brn 4220745
- D-alpha-Glutamine, N(sup 2)-(N-(N-acetylmuramoyl)-L-alanyl)-
- D-alpha-Glutamine, N2-(N-(N-acetylmuramoyl)-L-alanyl)-
- D-α-Glutamine, N-(N-acetylmuramoyl)-L-alanyl-
- D-α-Glutamine, N2-[N-(N-acetylmuramoyl)-L-alanyl]-
- MDP
- MDP-<span class="text-smallcaps">D</span>
- Muramoyl dipeptide
- Muramyl dipeptide
- N(sup 2)-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine
- N-(Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-isoglutamine
- N-(Acetylmuramoyl)alanyl-<span class="text-smallcaps">D</span>-isoglutamine
- N-(Acetylmuramoyl)alanyl-D-isoglutamine
- N-(N-Acetylmuramoyl)-<span class="text-smallcaps">L</smallcap>-alanyl-<smallcap>D</span>-α-glutamine
- N-Acetylmuramoyl dipeptide
- N-Acetylmuramoyl-<span class="text-smallcaps">L</smallcap>-alanine-<smallcap>D</span>-isoGln
- N-Acetylmuramoylalanyl-<span class="text-smallcaps">D</span>-isoglutamine
- N-Acetylmuramyl dipeptide
- N-Acetylmuramyl-L-Alanyl-D-Isoglutamine
- N-Acetylmuramyl-L-alanine-D-isoGln
- N2-(N-(N-Acetylmuramoyl)-L-alanyl)-D-alpha-glutamine
- N2-[N-(N-Acetylmuramoyl)-L-alanyl]-D-α-glutamin
- N2-[N-(N-acetilmuramoil)-L-alanil]-D-α-glutamina
- N-(N-Acetylmuramoyl)-L-alanyl-D-α-glutamine
- N-(Acetylmuramoyl)-L-alanyl-D-isoglutamine
- N-Acetylmuramoylalanyl-D-isoglutamine
- AC-MURAMYL-ALA-D-ISOGLUTAMINE
- n-acetylmuramyl-l-alanyl-d-isoglutamine hydrate
- AC-MURAMYL-ALA-D-GLN
- ADJUVANT PEPTIDE
- N-ACETYL-MURAMYL-L-ALA-D-ISOGLN
- n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamin
- N-AC-MURAMYL-ALA-D-GLU-NH2
- AC-MURAMYL-ALA-D-ISOGLN-OH
- L-18-MDP
- n(sup2)-(n-(n-acetylmuramoyl)-l-alanyl)-d-alpha-glutamine
- N-Acetylmuramyl-L-alanyl-D-isoglnamine hydrate
- AC-MURAMYL-ALA-D-GLU-NH2
- Adjuvant Peptide, Muramyl dipeptide
- N-AC-MURAMYL-ALA-D-GLU-NH2 2H2O
- Voir plus de synonymes
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8 produits concernés.
Ac-muramyl-Ala-D-Glu-NH₂
CAS :Muramyl dipeptide (MDP) inhibits HIV replication in CD4⁺ H9 lymphocytes..Formule :C19H32N4O11Degré de pureté :99.2%Couleur et forme :White PowderMasse moléculaire :492.48PAF (Platelet-Activating Factor, bovine heart)
CAS :Formule :C19H32N4O11Degré de pureté :95%Couleur et forme :In solution, ChloroformMasse moléculaire :492.48Muramyl dipeptide
CAS :MDP is a synthetic peptide promoting bone formation by modulating osteoclasts, osteoblasts, and Runx2 expression via MAPK pathways.Formule :C19H32N4O11Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :492.48N-Acetylmuramyl-L-alanyl-D-isoglutamine hydrate
CAS :Muramyl dipeptide is a component of the bacterial cell wall and is found in mycobacteria, mycoplasmas, spirochetes, and gram-positive bacteria. Muramyl dipeptide has been shown to induce the activation of macrophages and other cells by stimulating toll-like receptor 4. It also has significant cytotoxicity against various cancer cells, as well as potent inducers of ubiquitin ligases. The use of muramyl dipeptide in vitro was shown to inhibit replication of HIV-1 virus in human lymphocytes. This agent has also been used for the treatment of bowel disease.Formule :C19H32N4O11·xH2ODegré de pureté :Min. 96 Area-%Couleur et forme :PowderMasse moléculaire :492.48 g/molAdjuvant Peptide
CAS :<p>Adjuvant Peptide is a glycol ether that has been shown to have biological properties. It is used in the production of Immunoassays and other biochemicals. Adjuvant Peptide is an experimental model for immunity, as it stimulates cellular responses and alters the immune system's response to antigens. It shows potential for use in treating bowel diseases, such as ulcerative colitis, because of its ability to stimulate macrophage activity and induce cytokine production.</p>Formule :C19H32N4O11•2H2ODegré de pureté :Min. 95%Masse moléculaire :528.51 g/molAdjuvant Peptide
CAS :<p>Adjuvant peptide is a research tool that can be used in the study of protein interactions, pharmacology and cell biology. It can also be used as an inhibitor for ion channels or receptors. Adjuvant peptide has a molecular weight of 638.2 Da and a purity of > 98%.</p>Formule :C19H32N4O11Degré de pureté :Min. 95%Masse moléculaire :492.48 g/molN-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE
CAS :Formule :C19H32N4O11Degré de pureté :98%Masse moléculaire :492.4776Ref: IN-DA00DABS
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