CAS 59122-46-2
:Misoprostol
Description :
Misoprostol est un analogue synthétique de la prostaglandine E1, principalement utilisé en médecine pour sa capacité à induire des contractions utérines et à protéger la muqueuse gastrique. Il se caractérise par sa forme de poudre cristalline blanche à blanc cassé, soluble dans l'eau et dans des solvants organiques comme l'éthanol. Misoprostol agit en se liant aux récepteurs de prostaglandines, entraînant divers effets physiologiques, y compris la stimulation des contractions utérines, la maturation cervicale et l'inhibition de la sécrétion d'acide gastrique. Ses applications thérapeutiques incluent la prévention des ulcères gastriques chez les patients prenant des anti-inflammatoires non stéroïdiens (AINS), ainsi que son utilisation en obstétrique et en gynécologie pour l'avortement médical et la gestion des fausses couches. Le composé est généralement administré par voie orale ou vaginale, et sa pharmacocinétique implique une absorption et un métabolisme rapides, avec une demi-vie relativement courte. Le profil de sécurité de Misoprostol est généralement favorable, mais il peut provoquer des effets secondaires tels que des troubles gastro-intestinaux et une hyperstimulation utérine, nécessitant une surveillance attentive pendant son utilisation.
Formule :C22H38O5
InChI :InChI=1/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/s2
Code InChI :InChIKey=OJLOPKGSLYJEMD-YUQTXCCYNA-N
SMILES :C(=C/CC(CCCC)(C)O)\[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O
Synonymes :- (+-)-Methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
- (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester
- (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester
- (±)-15-Deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 Methyl Ester
- Cytotec
- Isprelor
- Misogon
- Misoprost
- Misoprostil
- Misotac
- Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11α,13E)-
- Sc 29333
- methyl (11alpha,13E)-11-hydroxy-16,16-dimethyl-9-oxoprost-13-en-1-oate
- methyl (11alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
- Voir plus de synonymes
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13 produits concernés.
MISOPROSTOL FOR SYSTEM SUITABILITY CRS
CAS :MISOPROSTOL FOR SYSTEM SUITABILITY CRSFormule :C22H38O5Masse moléculaire :382.5341Misoprostol
CAS :Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analoguesFormule :C22H38O5Couleur et forme :Colorless Light Yellow Liquid ViscousMasse moléculaire :382.27192Misoprostol
CAS :Misoprostol, a prostaglandin E1 derivative, has a strong inhibitory effect on gastric acid secretion, while having a contractile effect on pregnancy.Formule :C22H38O5Degré de pureté :99.78%Couleur et forme :Water-Soluble Viscous LiquidMasse moléculaire :382.53Misoprostol (0.10% wt/v in METHYL ACETATE), min. 97%
CAS :Formule :C22H38O5Degré de pureté :min. 97%Couleur et forme :White to Yellowish Oil (SOLUTION IN 10% METHYL ACETATE)Masse moléculaire :382.53Misoprostol (Mixture of Diastereomers)
CAS :Formule :C22H38O5Couleur et forme :Pale Yellow OilMasse moléculaire :382.54Misoprostol
CAS :Formule :C22H38O5Degré de pureté :≥ 99.0%Couleur et forme :Colourless to light yellow liquidMasse moléculaire :382.53Misoprostol
CAS :Produit contrôlé<p>Applications Misoprostol is a cytoprotective prostaglandin PGE1 analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Graham, Y., et al.: Lancet, 2, 1277 (1988); Graham, D.Y., et al.: Ann. Int. Med., 119, 257 (1993); Fletcher, H., et al.: Obstet. Gynecol., 83, 244 (1994);<br></p>Formule :C22H38O5Couleur et forme :Light Yellow ViscousMasse moléculaire :382.53Misoprostol, 1% in cellulose
CAS :Produit contrôléFormule :C22H38O5Couleur et forme :Single SolutionMasse moléculaire :382.53Misoprostol - 1% in cellulose
CAS :Produit contrôlé<p>Misoprostol is a nonsteroidal anti-inflammatory drug that is used for the treatment of dysmenorrhea and chronic non-specific low back pain. Misoprostol is also used in nephrology dialysis to decrease blood pressure, heart rate, and fluid retention in patients with congestive heart failure. It has been shown that misoprostol can be used to prevent preterm labor in pregnant women with a statistically significant reduction in the risk of miscarriage, preterm birth, and neonatal death. It has been shown that misoprostol can be administered orally or vaginally for the prevention of preterm labor. The pharmacokinetic properties of misoprostol are dose-dependent; higher doses result in faster absorption. Clinical relevance is dependent on the concentration-time curve, which determines how quickly the drug reaches its peak concentration. The clinical relevance of misoprostol is determined by the dose group (low dose or high dose), as well as diastolic</p>Formule :C22H38O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :382.53 g/molMisoprostol
CAS :Produit contrôlé<p>Misoprostol is a prostaglandin E1 analogue that is used for the prevention and treatment of peptic ulcers. It also has been shown to reduce the risk of gastric cancer in the general population, although this effect may be limited to patients with a history of nonsteroidal anti-inflammatory drug use. Misoprostol has been found to be more effective in women who have already given birth than in those who have not, with a statistically significant reduction in the incidence of pregnancy during long-term use. Misoprostol is metabolized by cytochrome P450 enzymes and excreted primarily through the kidneys. The drug's pharmacokinetic properties are dependent on diastolic blood pressure, body mass index, and levels of blood sampling. Intrauterine placement can also increase its efficacy as it bypasses first-pass metabolism.</p>Formule :C22H38O5Degré de pureté :Min. 95%Couleur et forme :Colorless Clear LiquidMasse moléculaire :382.53 g/mol
