CAS 6610-42-0

Benzyloxycarbonyl-L-glutaminylglycine

Description :

Benzyloxycarbonyl-L-glutaminylglycine, communément appelé Z-Glu-Gly, est un dérivé peptidique synthétique caractérisé par la présence d'un groupe protecteur benzyloxycarbonyle (Z) sur le résidu de glutamine. Ce composé est généralement utilisé dans la synthèse de peptides et la recherche en raison de sa stabilité et de sa capacité à protéger le groupe amino lors des réactions chimiques. La structure se compose d'une glutamine (Glu) et d'une glycine (Gly) liées par une liaison peptidique, ce qui en fait un dipeptide. Le groupe Z améliore la solubilité et la réactivité de la molécule, facilitant son utilisation dans diverses applications biochimiques. Il est souvent utilisé dans la synthèse de peptides et de protéines plus complexes, servant de bloc de construction dans le développement de produits pharmaceutiques et biochimiques. Le composé est généralement stable dans des conditions de laboratoire standard, mais peut être sensible à des acides ou des bases forts, ce qui peut entraîner l'hydrolyse de la liaison peptidique. Comme pour de nombreux dérivés peptidiques, il est important de le manipuler avec précaution, en suivant les protocoles de sécurité appropriés.

Formule : C₁₅H₁₉N₃O₆

InChI : InChI=1S/C15H19N3O6/c16-12(19)7-6-11(14(22)17-8-13(20)21)18-15(23)24-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H2,16,19)(H,17,22)(H,18,23)(H,20,21)/t11-/m0/s1

Code InChI : InChIKey=SOUXAAOTONMPRY-NSHDSACASA-N

SMILES : [C@H](C(NCC(O)=O)=O)(NC(OCC1=CC=CC=C1)=O)CCC(N)=O

Synonymes :

• 2-[[(2S)-5-Amino-5-oxo-2-(phenylmethoxycarbonylamino)pentanoyl]amino]acetic acid
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutaminylglycine
• Carbobenzoxy-<span class="text-smallcaps">L</span>-glutaminylglycine
• Glycine, N-(N²-carboxy-<span class="text-smallcaps">L</span>-glutaminyl)-, N-benzyl ester
• Glycine, N-(N²-carboxy-<span class="text-smallcaps">L</span>-glutaminyl)-, N²-benzyl ester
• Glycine, N-[N²-[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminyl]-
• Glycine, N²-[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminyl-
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutaminylglycine
• N²-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminylglycine
• N^α-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutaminylglycine
• NSC 186901
• N~2~-[(benzyloxy)carbonyl]glutaminylglycine
• Z-Gln-Gly-OH
• Glycine, N-(N2-carboxy-L-glutaminyl)-, N2-benzyl ester
• Glycine, N-[N2-[(phenylmethoxy)carbonyl]-L-glutaminyl]-
• Glycine, N2-[(phenylmethoxy)carbonyl]-L-glutaminyl-
• Glycine, N-(N2-carboxy-L-glutaminyl)-, N-benzyl ester

N-Benzyloxycarbonyl-L-glutaminylglycine, 98%

CAS : 6610-42-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formule : C₁₅H₁₉N₃O₆

Degré de pureté : 98%

Couleur et forme : White to pale cream, Powder

Masse moléculaire : 337.33

Ref: 02-H65088

Z-Gln-Gly-OH

CAS : 6610-42-0

Substrate for tissue transaminase. De Macédo et al. described a direct continuous spectrophotometric assay for transglutaminase (TGase) activity.

Formule : C₁₅H₁₉N₃O₆

Degré de pureté : > 99%

Couleur et forme : White Powder

Masse moléculaire : 337.33

Ref: 01-4002246

Z-GLN-GLY-OH

CAS : 6610-42-0

Formule : C₁₅H₁₉N₃O₆

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 337.3279

Ref: IN-DA00FAC9

Z-GLN-GLY-OH

CAS : 6610-42-0

Z-GLN-GLY-OH

Degré de pureté : 98%

Masse moléculaire : 337.33g/mol

Ref: 54-OR1015448

Z-Gln-Gly

CAS : 6610-42-0

Z-Gln-Gly is a protected dipeptide, which is commonly used as an intermediate in peptide synthesis. It is derived from the amino acids glutamine and glycine, with the N-terminal glutamine being protected by a benzyloxycarbonyl (Z or Cbz) group. This protective group is essential for preventing undesirable reactions at the amine site during peptide chain elongation.The primary mode of action for Z-Gln-Gly involves its use in solid-phase peptide synthesis, where the Z-group safeguards the amine functionality. This protection allows for selective reactions at other sites of the molecule until the final deprotection step, facilitating the sequential addition of amino acids.Z-Gln-Gly is used predominantly in research and development within biochemical and pharmaceutical laboratories. Its applications are critical in the synthesis of longer peptide chains and peptide-based drugs, where precision and control over the peptide structure are paramount for investigating biological processes and therapeutic functions.

Formule : C₁₅H₁₉N₃O₆

Degré de pureté : Min. 95%

Masse moléculaire : 337.33 g/mol

Ref: 3D-SZQ-3190

Z-Gln-Gly-OH

CAS : 6610-42-0

Z-Gln-Gly-OH is a synthetic dipeptide, which is a modified amino acid sequence commonly used in biochemical applications. It consists of a carbobenzoxy-protected glutamine and a glycine residue. This compound originates from custom organic synthesis, derived through specific chemical protocols to introduce protective groups that block reactive sites on the amino acids. This controlled modification alters the peptide's stability and solubility.The mode of action involves the protection of active sites during complex syntheses, enabling the sequential construction of peptide chains without unintended reactions. This protection is critical in solid-phase peptide synthesis methodologies where precision and specificity of reactions are paramount. The Z-group (benzyloxycarbonyl) ensures the stability of glutamine under various chemical conditions, preventing side reactions that may compromise the integrity of peptide constructs.In research, Z-Gln-Gly-OH finds applications in the design of peptide-based inhibitors, structural studies, and the synthesis of longer chain peptides that mimic biologically relevant structures. The protection strategy allows scientists to develop and manipulate peptides with high fidelity, facilitating advancements in understanding protein functions and interactions in physiological contexts.

Formule : C₁₅H₁₉N₃O₆

Degré de pureté : Min. 95%

Couleur et forme : Powder

Masse moléculaire : 337.33 g/mol

Ref: 3D-FG111459

(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid

CAS : 6610-42-0

Formule : C₁₅H₁₉N₃O₆

Degré de pureté : 98%

Masse moléculaire : 337.332

Ref: 10-F222428