
CAS 677331-12-3
:Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
6 produits concernés.
iCRT 14
CAS :Formule :C21H17N3O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :375.4436iCRT 14
CAS :<p>iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).</p>Formule :C21H17N3O2SDegré de pureté :99.8% - 99.97%Couleur et forme :SolidMasse moléculaire :375.44iCRT-14
CAS :Produit contrôlé<p>Applications A potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Studies suggest that it may directly influence the interaction between β-catenin and TCF4. It induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.<br>References Gonsalves, F.C. et al.: Proc. Natl. Acad. Sci. USA, 108, 5954 (2011); Watanabe, K. et al.: Proc. Natl. Acad. Sci. USA, 108, 5929 (2011);<br></p>Formule :C21H17N3O2SCouleur et forme :NeatMasse moléculaire :375.44





