CAS 68-89-3
:Dipyrone
Description :
Dipyrone, également connu sous le nom de métamizole, est un analgésique et un antipyrétique non opioïde couramment utilisé pour soulager la douleur et réduire la fièvre. Il est classé comme un dérivé de la pyrazolone et est connu pour ses puissantes propriétés analgésiques. Dipyrone est généralement administré sous forme de sel sodique, ce qui améliore sa solubilité dans l'eau. Le composé se caractérise par sa capacité à inhiber la synthèse des prostaglandines, réduisant ainsi la douleur et l'inflammation. Il est souvent utilisé dans des contextes cliniques pour la gestion de la douleur sévère, en particulier lorsque d'autres analgésiques sont inefficaces. Cependant, Dipyrone a été associé à des effets secondaires graves, notamment l'agranulocytose, une diminution potentiellement mortelle du nombre de globules blancs, ce qui a conduit à son utilisation restreinte dans certains pays. La substance est généralement bien absorbée lorsqu'elle est administrée par voie orale ou intraveineuse, et ses effets peuvent être rapides, ce qui en fait une option précieuse dans les scénarios de douleur aiguë. Malgré son efficacité, les professionnels de santé doivent peser les avantages et les risques lors de la prise en compte de Dipyrone pour le traitement des patients.
Formule :C13H16N3NaO4S
InChI :InChI=1/C13H19N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8,10,12H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/rC13H18N3NaO4S/c1-10-12(14(2)9-22(19,20)21-17)13(18)16(15(10)3)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3
Code InChI :InChIKey=CEOUXRNZHGKECQ-UHFFFAOYSA-N
SMILES :O=C1N(N(C)C(C)=C1N(CS(=O)(=O)O)C)C2=CC=CC=C2.[Na]
Synonymes :- Algocalmin
- Algopyrin
- Amoloid HV
- Amoloid LV
- Anador
- Analgin
- Analgin DAB10
- Analgine
- Andolor
- Arpf
- Collatex A/RE
- Collatex Arm Extra
- CollatexA/RE Extra
- Conmel
- Diprofarn
- Dipyrone,hydrate
- Duckammon
- E 403
- Gifaril
- Kimica Algin NH
- Kimitsu Algin NH
- Lisador
- Manutex PC-MV
- Metamizol
- Metamizole
- Metamizole Sodium
- Metamizole sodium salt
- Metapyrin
- Methamizole sodium
- Methampyrone
- Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt
- Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1)
- Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt
- Methylmelubrin
- Metilon
- Narone
- Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
- Neo-melubrine
- Noramidopyrine methanesulfonate sodium
- Noramidopyrine methanesulfonate sodium salt
- Noraminophenazone methanesulfonate sodium salt
- Noraminophenazone sodium mesylate
- Novalgetol
- Novalgin
- Novamidazophen
- Novaminophenazone
- Novaminsulfone
- Novaminsulfone sodium
- Novaminsulfonium
- Novaminsulfonum
- Noveltex
- Optalgin
- Pharmalgine
- Protamon S
- Pyralgine
- Pyretin
- Pyretin (pharmaceutical)
- Restriva
- Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate
- Sodium (antipyrinylmethylamino)methanesulfonate
- Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate
- Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
- Sodium metamizole
- Sodium noramidopyrine methanesulfonate
- Sodium novaminsulfonate
- Sulpin
- Sulpyrin
- Sulpyrine
- [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium
- [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
- [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt
- [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium
- [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio
- sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
- sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)
- Dipyrone
- BENZALAGEN
- (antipyrinylmethylamino)-methanesulfonicacimonosodiumsalt
- SODIUM [(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)-METHYL-AMINO]METHANESULFONATE
- 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate
- (antipyrinylmethylamino)methanesulfonicacidsodiumsalt
- 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium
- dipyron
- LABOTEST-BB LT00771955
- (antipyrinylmethylamino)-methanesulfonicacisodiumsalt
- DIPYRONE SODIUM
- 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium
- METAMIZOL SODIUM
- SODIUM DIPYRONE
- Voir plus de synonymes
Trier par
Degré de pureté (%)
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11 produits concernés.
Metamizole Sodium Salt
CAS :Formule :C13H16N3NaO4SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Almost white powder to crystalMasse moléculaire :333.34Dipyrone
CAS :Formule :C13H17N3NaO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.3465Metamizole sodium
CAS :Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.Formule :C13H16N3NaO4SDegré de pureté :99.52%Couleur et forme :White Or Almost White Crystal PowderMasse moléculaire :333.34Metamizole Sodium Salt (Dipyrone)
CAS :Formule :C13H16N3O4S·NaCouleur et forme :White To Off-White SolidMasse moléculaire :310.35 22.99Metamizol sodium
CAS :Produit contrôléFormule :C13H16N3O4S·NaCouleur et forme :NeatMasse moléculaire :333.34Dipyrone
CAS :Produit contrôlé<p>Applications Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Neuroprotective & Neuroresearch Product.<br>References Reith, J., et al.: Lancet, 347, 422 (1996), Grau, A., et al.: J. Neurol. Sci., 171, 115 (1999), Schwarz, S., et al.: Neurology, 2000, 54, 354 (2000), Greer, D., et al.: Stroke, 39, 3029 (2008),<br></p>Formule :C13H16N3O4S·NaCouleur et forme :WhiteMasse moléculaire :333.34Dipyrone-d3
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.<br>References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008);<br></p>Formule :C13H13D3N3NaO4SCouleur et forme :Off-WhiteMasse moléculaire :336.36Dipyrone
CAS :<p>Dipyrone is an anti-inflammatory and analgesic drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to inhibit the production of prostaglandins, which are involved in inflammation, by inhibiting cyclooxygenase. The polymerase chain reaction (PCR) method is a biochemical technique used to amplify a segment of DNA, typically for use as a genetic marker or for cloning a particular gene. A PCR assay can be used to detect the presence of bacterial DNA in a sample. Dipyrone has been shown to possess chemiluminescence activity, which is indicative of its ability to bind with DNA. This binding inhibits transcription and replication and may be responsible for the toxic effects on epidermal cells observed in animal studies. Dipyrone also has been shown to have anti-inflammatory activities through its inhibition of cyclooxygenase and its ability to inhibit neutrophil migration and function.</p>Formule :C13H16N3NaO4SDegré de pureté :Min. 95%Couleur et forme :White SolidMasse moléculaire :333.34 g/mol
