CAS 718630-59-2

PHA-793887

CAS : 718630-59-2

PHA-793887

Degré de pureté : ≥98%

Masse moléculaire : 361.48g/mol

Ref: 54-BUP06949

PHA-793887

CAS : 718630-59-2

Formule : C₁₉H₃₁N₅O₂

Masse moléculaire : 361.49

Ref: 4Z-P-356001

PHA-793887

CAS : 718630-59-2

PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.

Formule : C₁₉H₃₁N₅O₂

Degré de pureté : 98.02% - >99.99%

Couleur et forme : Solid

Masse moléculaire : 361.48

Ref: TM-T2113

PHA 793887

CAS : 718630-59-2

Inhibitor of cyclin dependend kinases

Formule : C₁₉H₃₁N₅O₂

Degré de pureté : Min. 95%

Couleur et forme : Solid

Masse moléculaire : 361.24778

Ref: 3D-FM145343

PHA-793887

Produit contrôlé

CAS : 718630-59-2

Stability Hygroscopic
Applications PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.
References Alzani, R. et al.: Exp. Hematol., 38, 259 (2010); Locatelli, G. et al.: Mol. Cancer Ther., 9, 1265 (2010); Brasca, M. et al.: Bioorg. Med. Chem., 18, 1844 (2010);

Formule : C₁₉H₃₁N₅O₂

Couleur et forme : Neat

Masse moléculaire : 361.48

Ref: TR-P294480