CAS 7772-94-3

2-(Acétylamino)-2-désoxy-β-D-mannopyranose

Description :

2-(Acétylamino)-2-désoxy-β-D-mannopyranose, communément appelé N-acétylmannosamine, est un acide aminé qui joue un rôle significatif dans divers processus biologiques, en particulier dans la synthèse des glycoprotéines et des glycolipides. Ce composé présente un groupe acétylamino à la position C-2 de l'anneau de mannopiranose, ce qui contribue à ses propriétés biochimiques. Il s'agit généralement d'un solide cristallin blanc à blanc cassé qui est soluble dans l'eau, reflétant sa nature polaire en raison des groupes hydroxyle et amino. La présence du groupe acétylamino améliore sa réactivité et lui permet de participer à diverses voies métaboliques, y compris celles impliquées dans la biosynthèse de l'acide sialique. La N-acétylmannosamine est également importante dans les processus de signalisation et de reconnaissance cellulaire, ce qui en fait un sujet d'intérêt dans la recherche liée aux interactions cellulaires et aux mécanismes de maladies. Son numéro CAS, 7772-94-3, est utilisé pour l'identification dans les bases de données chimiques et les contextes réglementaires. Dans l'ensemble, ce composé est significatif tant en biochimie que dans les applications pharmaceutiques.

Formule : C₈H₁₅NO₆

InChI : InChI=1S/C8H15NO6/c1-3(11)9-5-7(13)6(12)4(2-10)15-8(5)14/h4-8,10,12-14H,2H2,1H3,(H,9,11)/t4-,5+,6-,7-,8-/m1/s1

Code InChI : InChIKey=OVRNDRQMDRJTHS-OZRXBMAMSA-N

SMILES : N(C(C)=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O

Synonymes :

• 2-(Acetylamino)-2-Deoxyhexopyranose Hydrate
• 2-(Acetylamino)-2-deoxy-β-<span class="text-smallcaps">D</span>-mannopyranose
• 2-(acetylamino)-2-deoxy-alpha-D-gulopyranose
• Mannopyranose, 2-acetamido-2-deoxy-, β-<span class="text-smallcaps">D</span>-
• N-Acetyl-D-mannosamine monohydrate
• β-<span class="text-smallcaps">D</span>-Mannopyranose, 2-(acetylamino)-2-deoxy-
• 2-(Acetylamino)-2-deoxy-β-D-mannopyranose
• β-D-Mannopyranose, 2-(acetylamino)-2-deoxy-
• Mannopyranose, 2-acetamido-2-deoxy-, β-D-

N-Acetylmannosamine

CAS : 7772-94-3

Formule : C₈H₁₅NO₆

Degré de pureté : 95%

Couleur et forme : Solid

Masse moléculaire : 221.2078

Ref: IN-DA003SOW

N-Acetyl-D-mannosamine

CAS : 7772-94-3

Formule : C₈H₁₅NO₆·xH₂O

Degré de pureté : ≥ 98.0%

Couleur et forme : White to off-white powder

Masse moléculaire : 221.21 (anhydrous)

Ref: 7W-GK3319

2-(Acetamido)-2-deoxy-β-D-mannopyranose

CAS : 7772-94-3

2-(Acetamido)-2-deoxy-β-D-mannopyranose

Degré de pureté : 97% (Monohydrate)

Masse moléculaire : 221.21g/mol

Ref: 54-OR8153

N-Acetyl-D-mannosamine

CAS : 7772-94-3

N-Acetyl-D-mannosamine

Couleur et forme : White To Off White Powder

Masse moléculaire : 239.22g/mol

Ref: 54-BIA1221

Cyclic N-Acetyl-D-mannosamine

CAS : 7772-94-3

Cyclic N-Acetyl-D-mannosamine is used for sialic acid synthesis and as a precursor for biologically active compounds.

Formule : C₈H₁₅NO₆

Degré de pureté : 99.18% - 99.72%

Couleur et forme : White Crystal Powder

Masse moléculaire : 221.21

Ref: TM-T4725

N-Acetyl-D-mannosamine

CAS : 7772-94-3

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. Glycoproteins normally have some level of glycan sialylation, but incomplete sialylation can reduce their therapeutic effect when produced recombinantly. To improve performance, cell lines and culture media can be adjusted. The GNE enzyme controls the efficiency of sialylation in human cell lines, making it crucial for producing effective recombinant glycoprotein drugs. Adding ManNAc and other supplements to culture media improves sialylation, which boosts drug yield, increases stability and half-life, and lowers immune reactions by reducing antibody formation.It has also been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

Formule : C₈H₁₅NO₆

Degré de pureté : Min. 97.5 Area-%

Masse moléculaire : 221.21 g/mol

Ref: 3D-Z-1000

N-Acetyl-D-mannosamine - low endotoxin grade

CAS : 7772-94-3

Please enquire for more information about N-Acetyl-D-mannosamine - low endotoxin grade including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formule : C₈H₁₅NO₆

Masse moléculaire : 221.21 g/mol

Ref: 3D-Z-1082

N-Acetyl-D-mannosamine

CAS : 7772-94-3

Degré de pureté : 95%

Masse moléculaire : 221.21

Ref: 10-F493709

N-Acetyl-D-mannosamine

CAS : 7772-94-3

N-Acetyl D-mannosamine (ManNAc) is an aldohexose (2-acetamido-2-deoxymannose) in which the axial hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). It has been reported that N-acetyl D-mannosamine supplementation, may provide novel means to break the link between obesity and hypertension (Peng, 2019). N-Acetyl-D-mannosamine and N-acetyl-D-glucosamine are the essential precursors of sialic acid, the specific monomer of polysialic acid, a bacterial pathogenic determinant, for example, Escherichia coli K1 uses both amino sugars as carbon sources. It has been reported that ManNAc can be used as a treatment for hereditary inclusion body myopathy, an adult-onset, progressive neuromuscular disorder and also for renal disorders involving proteinuria and hematuria due to podocytopathy and/or segmental splitting of the glomerular basement membrane (Galeano, 2007).

Formule : C₈H₁₅NO₆

Degré de pureté : Min. 98 Area-%

Couleur et forme : White Powder

Masse moléculaire : 221.21 g/mol

Ref: 3D-MA05269