CAS 78111-17-8

acide 1,7-dioxaspiro[5.5]undec-10-ène-2-propanoïque, α,5-dihydroxy-α,10-diméthyl-8-[(1R,2E)-1-méthyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-méthyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-méthylènespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propényle]-, (αR,2S,5R,6R,8S)-

Description :

acide 1,7-dioxaspiro[5.5]undec-10-ène-2-propanoïque, α,5-dihydroxy-α,10-diméthyl-8-[(1R,2E)-1-méthyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-méthyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-méthylènespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propényle]-, (αR,2S,5R,6R,8S)- est un composé organique complexe caractérisé par sa structure moléculaire complexe, qui comprend plusieurs groupes fonctionnels tels que dioxaspiro, hydroxyle et moieties d'acide propanoïque. Ce composé présente une chiralité, indiquée par ses descripteurs stéréochimiques, suggérant qu'il peut exister sous plusieurs formes énantiomériques. Sa complexité structurelle peut conférer des propriétés chimiques uniques, influençant potentiellement sa réactivité et ses interactions avec les systèmes biologiques. La présence de plusieurs cycles et centres stéréogéniques suggère qu'il pourrait avoir des applications en pharmacie ou comme intermédiaire synthétique en chimie organique. De plus, le numéro CAS du composé, 78111-17-8, permet une identification et une référence faciles dans les bases de données chimiques. Dans l'ensemble, cette substance représente un exemple fascinant de la synthèse organique moderne et de la diversité structurelle dans les composés chimiques.

Formule : C₄₄H₆₈O₁₃

InChI : InChI=1/C44H68O13/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49)/b10-9+/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37?,38+,39?,41-,42+,43-,44-/m1/s1

Code InChI : InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N

SMILES : O[C@H]1[C@@]2(O[C@]([C@@H](/C=C/[C@@H]3O[C@]4(CC3)O[C@@]5([C@@](CC4)(O[C@]([C@H](C[C@H](C)[C@]6(O[C@]7(CC[C@H]6C)CCCCO7)[H])O)(C(=C)[C@H]5O)[H])[H])[H])C)(CC(C)=C2)[H])O[C@H](C[C@@](C(O)=O)(C)O)CC1

Synonymes :

• (αR,2S,5R,6R,8S)-α,5-Dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-1,7-dioxaspiro[5.5]undec-10-ene-2-propanoic acid
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4′aR,5R,6′S,8′R,8′aS)-octahydro-8′-hydroxy-6′-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, (αR,2S,5R,6R,8S)-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8'-hydroxy-6'-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2'R-[2'α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4'aβ,6'β[1S*,3S*(2S*,3R*,6S*)],8'α,8'aα]]-
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, α,5-dihydroxy-α,10-dimethyl-8-[1-methyl-3-[octahydro-8′-hydroxy-6′-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undec-2-yl)butyl]-7′-methylenespiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran]-5-yl]-2-propenyl]-, [2′R-[2′α[R*[1R*[2S*(R*),5R*,6R*,8S*],2E]],4′aβ,6′β[1S*,3S*(2S*,3R*,6S*)],8′α,8′aα]]-
• 1,7-Dioxaspiro[5.5]undecane, acanthifolicin deriv.
• 35-Demethyl-DTX 1
• 35-Demethyldinophysistoxin 1
• Acanthifolicin, 9,10-deepithio-9,10-didehydro-
• Nsc 677083
• Okadaic acid
• Spiro[furan-2(3H),2′(3′H)-pyrano[3,2-b]pyran], acanthifolicin deriv.
• (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(2R,3E)-4-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]but-3-en-2-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid
• 78111-17-8
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoic acid, alpha,5-dihydroxy-alpha,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(3H),2'(3'H)-pyrano[3,2-b]pyran]-5-yl]-2-propen-1-yl]-, (alphaR,2S,5R,6R,8S)-
• OKADAIC ACID, 25 UG*
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIOFOLICIN
• Okadaic acid, free acid >98%
• Okadic acid
• OA
• OKADAIC ACID >95% PROTEIN PHOSPHATASE I
• 1,7-Dioxaspiro5.5undec-10-ene-2-propanoic acid, .alpha.,5-dihydroxy-.alpha.,10-dimethyl-8-(1R,2E)-1-methyl-3-(2R,4aR,5R,6S,8R,8aS)-octahydro-8-hydroxy-6-(1S,3S)-1-hydroxy-3-(2S,3R,6S)-3-methyl-1,7-dioxaspiro5.5undec-2-ylbutyl-7-methylenespirofuran-2(3H),2
• 9,10-DEEPITHIO-9,10-DIDEHYDROACANTHIFOLICIN
• OKADAIC ACID FREE ACID
• Okadaic acid,97%
• OKADAICACID,HIGHPURITY
• 9,10-deepithio-9,10-didehydro-acanthifolici
• OKADAIC ACID AMMONIUM SALT WATER-SOLUBLE ANALOG
• OKADAIC ACID, 98+%
• OKADAIC ACID, PROROCENTRUM CONCAVUM
• Ocadaic Acid
• HALOCHONDRINE A
• Okadaic acid from Prorocentrum concavum,OA
• Okadaic acid 35-Demethyl-DTX 1 NSC 677083 35-Demethyldinophysistoxin 1
• OKADAIC ACID SODIUM SALT 98+%
• Blue mussel, homogenized (Okadaic acid)
• 1,7-Dioxaspiro[5.5]undec-10-ene-2-propanoicacid, a,5-dihydroxy-a,10-dimethyl-8-[(1R,2E)-1-methyl-3-[(2R,4'aR,5R,6'S,8'R,8'aS)-octahydro-8'-hydroxy-6'-[(1S,3S)-1-hydroxy-3-[(2S,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl]-7'-methylenespiro[furan-2(
• OKADAIC ACID FROM PROROCENTRUM SP.
• 9,45-Seco-10-demercapto-9,10-didehydroacanthifolicin
• Okadaicacid,Prorocentrumconcavum,highpurity

Okadaic acid, 98%

CAS : 78111-17-8

Okadaic acid, is used as an activator of PKC and inhibitor of PP1 and PP2A phosphatases. The hydrophobic backbone of okadaic acid enables it to enter cells where it stimulates intracellular protein phosphorylation. It mimics the effects of insulin, enhances transmitter release at neuromuscular junct

Formule : C₄₄H₆₈O₁₃

Degré de pureté : 98%

Couleur et forme : White, Solid

Masse moléculaire : 805.02

Ref: 02-J60155

Okadaic acid

CAS : 78111-17-8

Formule : C₄₄H₆₈O₁₃

Couleur et forme : Solid

Masse moléculaire : 805.0029

Ref: IN-DA003AXF

Okadaic acid, Prorocentrum concavum, high purity

CAS : 78111-17-8

Formule : C₄₄H₆₈O₁₃

Degré de pureté : >98%

Masse moléculaire : 805.015

Ref: 10-M02211

Okadaic acid

CAS : 78111-17-8

Formule : C₄₄H₆₈O₁₃

Degré de pureté : ≥ 97.0%

Couleur et forme : White crystalline powder or solid

Masse moléculaire : 805.02

Ref: 7W-GL7691

Okadaic acid, free acid

CAS : 78111-17-8

Okadaic acid, free acid

Formule : C₄₄H₆₈O₁₃

Degré de pureté : >98%

Couleur et forme : white lyophilized solid

Masse moléculaire : 805.00g/mol

Ref: 54-BIM1576

Okadaic Acid

CAS : 78111-17-8

Applications Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a potent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular physiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis. OA. EU regulated marine toxin.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Valdiglesia, V., et al.: J. Toxicol. Enviro. Health., 75, 844 (2012); Kamat, P.K., et al.: Life. Sci., 90, 713 (2012); Valdiglesias, V., et al.: BMC. Genomics., 13, 46 (2012);

Formule : C₄₄H₆₈O₁₃

Couleur et forme : Neat

Masse moléculaire : 805.00

Ref: TR-O515500

Okadaic acid

CAS : 78111-17-8

Inhibitor of PP1 and PP2A protein phosphatases

Formule : C₄₄H₆₈O₁₃

Degré de pureté : Min. 95%

Masse moléculaire : 805 g/mol

Ref: 3D-FO73140

Okadaic acid

CAS : 78111-17-8

Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.

Formule : C₄₄H₆₈O₁₃

Degré de pureté : 98%

Couleur et forme : White Crystals Or Powder

Masse moléculaire : 805

Ref: TM-T16381