CAS 80875-87-2

2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution

CAS : 80875-87-2

2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt is a circularization agent that can be used in the efficient method for the synthesis of DNA. It inhibits the growth of bacteria by binding to their DNA and preventing transcription. 2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt has shown inhibitory effects against tuberculosis and other infectious diseases, including diphtheria, tetanus, typhoid fever, and malaria. This drug also prevents the replication of viral RNA. The inhibition occurs through an analog mechanism at the level of nucleic acid synthesis or polymerase chain reaction (PCR). The thiophosphate group is cleaved from the triphosphate moiety in the presence of metal ions such as Zn2+, Mg2+, Mn2+, or Ca2+. The active form is enzymatically hydrolyzed by covalent enzyme activity to

Formule : C₁₀H₁₆N₅O₁₁P₃S·xLi

Degré de pureté : Min. 95%

Masse moléculaire : 507.25 g/mol

Ref: 3D-ND32070