CAS 851881-59-9

(R)-ADX-47273

CAS : 851881-59-9

(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).

Formule : C₂₀H₁₇F₂N₃O₂

Degré de pureté : 99.87%

Couleur et forme : Solid

Masse moléculaire : 369.36

Ref: TM-T13441

(R)-ADX-47273

CAS : 851881-59-9

(R)-ADX-47273

Degré de pureté : ≥98%

Masse moléculaire : 369.36g/mol

Ref: 54-BUP09666

(R)-ADX 47273

CAS : 851881-59-9

Positive allosteric modulator of the metabotropic glutamate receptor mGluR5 with EC50 in submicromolar range. The compound is able to increase mGluR5 function in vitro and in vivo. A study showed that ADX-47273 enhanced fear extinction learning as well as improved reversal learning in experimental animals.

Formule : C₂₀H₁₇F₂N₃O₂

Degré de pureté : Min. 95%

Couleur et forme : Solid

Masse moléculaire : 369.36 g/mol

Ref: 3D-BA166488