CAS 852536-39-1

4,4'-(7-Hydroxychroman-3,4-diyl)diphenol

CAS : 852536-39-1

4,4'-(7-Hydroxychroman-3,4-diyl)diphenol (DHP) is a synthetic small molecule that is being studied for its anticancer activity. DHP has been shown to inhibit mitochondrial membrane potential, which is essential for tumor cell proliferation and metastasis. DHP has also been shown to have toxicities in vivo, including increased levels of liver enzymes in mice. This drug has been used as a probe for the study of β-catenin signaling, and it has been shown to inhibit cancer cells with high levels of β-catenin. It also inhibits tumor growth in mice by inhibiting the initiation phase of mitosis. In addition, DHP may be able to reduce the risk of escalation from colon cancer to metastatic colorectal cancer by targeting mitochondria. There are currently no clinical trials using this drug as an anti-cancer therapy. However, there are some data suggesting that this drug may be promising

Formule : C₂₁H₁₈O₄

Degré de pureté : Min. 95%

Masse moléculaire : 334.4 g/mol

Ref: 3D-CJB53639

ME-143

CAS : 852536-39-1

ME-143, a 2nd-gen NADH oxidase inhibitor, blocks WNT/β-catenin pathway, active against various cancers in vitro/vivo.

Formule : C₂₁H₁₈O₄

Couleur et forme : Solid

Masse moléculaire : 334.37

Ref: TM-T73478