CAS 858478-91-8

3-Formyl-2-hydroxybenzonitrile

CAS : 858478-91-8

3-Formyl-2-hydroxybenzonitrile

Degré de pureté : ≥95%

Couleur et forme : Powder

Masse moléculaire : 147.13g/mol

Ref: 54-OR61339

3-Formyl-2-hydroxybenzonitrile

CAS : 858478-91-8

3-Formyl-2-hydroxybenzonitrile (3FHB) is a potent inhibitor of the E3 ligase that prevents ubiquitin from binding to its target proteins. It is used in cancer therapy as an activator of ubiquitination. 3FHB has been shown to be effective in inhibiting tumour growth and inducing apoptosis in a number of cancer cell lines, including those derived from breast, prostate, brain, and lung cancers. 3FHB also inhibits the proliferation of human colon adenocarcinoma cells by promoting ubiquitination of cyclin D1, which regulates the G1/S transition.

Formule : C₈H₅NO₂

Degré de pureté : Min. 95%

Masse moléculaire : 147.13 g/mol

Ref: 3D-IJB47891