CAS 861119-08-6

A 844606

Produit contrôlé

CAS : 861119-08-6

Applications A 844606 is an α7 nicotinic receptor agonists derived from tilorone (1).
References (1) Schrimpf, M.R., et al.: Bioorg. Medn. Chem. Letters., 22, 1633 (2012)

Formule : C₂₀H₂₀N₂O₂

Couleur et forme : Neat

Masse moléculaire : 320.38

Ref: TR-A101230

A 844606

CAS : 861119-08-6

A 844606 is a flavanones drug which has been shown to inhibit the proliferation of human tumor cells. It also induces tumor cell apoptosis and inhibits tumor growth in mice. A 844606 has been shown to bind to nicotinic acetylcholine receptors, and as such is an agonist for these receptors. It is a subtype-selective antagonist of nicotinic acetylcholine receptor subtypes α3β4 and α7, but not for α3β2. A 844606 has also been shown to have antitussive properties, indicating that it may be useful in the treatment of chronic obstructive pulmonary disease.

Formule : C₂₀H₂₀N₂O₂

Degré de pureté : Min. 95%

Masse moléculaire : 320.4 g/mol

Ref: 3D-LJB11908