CAS 867330-68-5

1,2,4-Benzotriazin-3-aMine, 7-(2,6-dichlorophenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-

Formule : C₂₆H₂₅Cl₂N₅O

Synonymes :

• 1,2,4-Benzotriazin-3-aMine, 7-(2,6-dichlorophenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-

TG-100435

CAS : 867330-68-5

TG-100435 is a novel multi-target oral protein tyrosine kinase inhibitor. The metabolic flux of TG100435 is entirely inhibited by methimazole and ketoconazole. In human liver microsomes or recombinant P450, the formation of TG100435 increases with the activity of cytochrome P450 reductase, suggesting that cytochrome P450 reductase may be involved.

Formule : C₂₆H₂₅Cl₂N₅O

Masse moléculaire : 494.42

Ref: TM-T202894