CAS 881970-80-5

iMDK

CAS : 881970-80-5

iMDK

Degré de pureté : ≥98%

Masse moléculaire : 376.4g/mol

Ref: 54-BUP07801

iMDK

CAS : 881970-80-5

iMDK quarterhydrate, a PI3K inhibitor, blocks MDK growth factor and enhances NSCLC treatment with MEK inhibitors, sparing normal cells.

Formule : C₂₁H₁₃FN₂O₂S

Degré de pureté : 99.99%

Couleur et forme : Solid

Masse moléculaire : 376.4

Ref: TM-T9460

Imdk

CAS : 881970-80-5

Imdk is a model system for the study of antitumor response. It has been shown to inhibit tumor growth in mice when combined with temozolomide treatment. Imdk also inhibits epidermal growth factor (EGF) and cancer cell proliferation. Imdk is an inhibitor of protein kinase C, which may be responsible for its antitumor effects. The mechanism by which Imdk inhibits EGF is not known but may be due to its ability to induce p21 expression in caco-2 cells, which causes the cell cycle arrest. Imdk also has anti-HIV activity, inhibiting HIV replication and decreasing viral loads in infected cells.

Formule : C₂₁H₁₃FN₂O₂S

Degré de pureté : Min. 95%

Masse moléculaire : 376.4 g/mol

Ref: 3D-GKB97080