CAS 894783-71-2
:Nintedanib Acid ((Z)-3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylic acid)
CAS :Lactams, nesoiFormule :C30H31N5O4Couleur et forme :Pale Yellow SolidMasse moléculaire :525.2376(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid
CAS :Formule :C30H31N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :525.5982Nintedanib Impurity 6 Ditrifluoroacetate
CAS :Formule :C30H31N5O4·2C2HF3O2Masse moléculaire :525.61 2*114.02Nintedanib Impurity 6-13C-d3
CAS :Formule :C2913CH28D3N5O4Couleur et forme :Yellow SolidMasse moléculaire :529.62Nintedanib Impurity 6
CAS :Formule :C30H31N5O4Couleur et forme :Yellow SolidMasse moléculaire :525.61(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3
CAS :Produit contrôléApplications (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3 is an intermediate used in the synthesis of Nintedanib Demethyl-O-glucuronic Acid-d3 (N478297), which is an isotopic analog of Nintedanib Demethyl-O-glucuronic Acid (N478295), a metabolite of the drug Nintedanib (N478290).
References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)Formule :C30D3H28N5O4Couleur et forme :NeatMasse moléculaire :528.617Nintedanib Carboxylic Acid
CAS :Formule :C30H31N5O4Couleur et forme :Yellow SolidMasse moléculaire :525.6BIBF 1202
CAS :BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).Formule :C30H31N5O4Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :525.6BIBF 1202
CAS :BIBF 1202 is a potent inhibitor of phospholipase A2, prostaglandin synthase and cyclooxygenase-2. It inhibits the production of arachidonic acid from membrane phospholipids and is used in cancer research. BIBF 1202 has been shown to have anti-tumour activity in a number of animal models, including human liver cancer cells. This molecule has also been shown to inhibit the activation of nuclear factor kappa B (NF-κB), which is involved in carcinogenesis.
Formule :C30H31N5O4Degré de pureté :Min. 95%Masse moléculaire :525.6 g/molRef: 3D-UKB78371
Produit arrêté
![(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylen…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00GU1U.jpg&w=3840&q=75)
![(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylen…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FD454387.jpg&w=3840&q=75)
