CAS 9011-18-1

Sulfate de dextrane sodique

Description :

Sulfate de dextrane sodique est un polysaccharide sulfaté dérivé du dextran, un glucane ramifié complexe. Il se caractérise par son poids moléculaire élevé et est généralement utilisé comme anticoagulant et dans diverses applications biomédicales. La substance apparaît sous forme de poudre blanche à blanc cassé et est soluble dans l'eau, formant une solution visqueuse. Sulfate de dextrane sodique présente une charge négative en raison des groupes sulfate, ce qui contribue à sa capacité à interagir avec des protéines et d'autres biomolécules, le rendant utile dans les systèmes de délivrance de médicaments et comme agent stabilisant dans diverses formulations. De plus, il a été étudié pour ses effets thérapeutiques potentiels, y compris des propriétés antivirales et anti-inflammatoires. Son profil de sécurité est généralement favorable, mais il peut provoquer des réactions indésirables chez certaines personnes, en particulier à des concentrations élevées. Comme pour toute substance chimique, des directives appropriées de manipulation et d'utilisation doivent être suivies pour garantir la sécurité et l'efficacité de ses applications.

Formule : H₂O₄S·xNa·xUnspecified

Synonymes :

• Asuro
• Colyonal
• Dexnon
• Dextralip 15
• Dextran Sulfate Sodium
• Dextran sodium sulfate
• Dextran sulfate sodium salt
• Dextran sulfuric acid ester sodium salt
• Dextran, hydrogen sulfate, sodium salt
• Dextransulfate sodium sulfur
• Dextrarine
• Dexulate
• MDS (polysaccharide)
• MDS-Kowa A

Dextran sulfate sodium salt - MW 40,000

CAS : 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (e.g., commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages when compared to other animal models of colitis, due to its simplicity and has many similarities to human inflammatory bowel disease.

Couleur et forme : Off-White Powder

Ref: 3D-YD31804

Dextran sulfate sodium salt - MW 9,000-16,000

CAS : 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Couleur et forme : Powder

Ref: 3D-YD31802

Dextran sulfate sodium salt (MW 5000)

CAS : 9011-18-1

Degré de pureté : 98%

Ref: 10-F554564

Dextran sulfate sodium - MW 5,000-8,000

CAS : 9011-18-1

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages, when compared to other animal models of colitis, due to its simplicity and similarities to human inflammatory bowel disease.

Formule : (C₆H₇Na₃O₁₄S₃)n

Degré de pureté : Min. 95%

Couleur et forme : Powder

Ref: 3D-YD31801

Dextran Sulphate Sodium Salt 30-50(DSS 35-50) ex. Leuconostoc Sp.Colitis Grade for molecular biology

CAS : 9011-18-1

Couleur et forme : White to off-white, Powder, Clear, Colourless to pale yellow

Masse moléculaire : made from Dextran 35 - 50 KDa

Ref: SR-76203

Dextran Sulphate Sodium Salt 500 (DSS 500) ex. Leuconostoc Sp. for molecular biology

CAS : 9011-18-1

Couleur et forme : White to pale yellow, Powder, Clear

Masse moléculaire : made from Dextran 500 KDa

Ref: SR-99629

Dextran sulfate sodium salt - MW 150,000

CAS : 9011-18-1

Induces ulceration; used to model inflammatory bowel disease

Degré de pureté : Min. 95%

Couleur et forme : Powder

Ref: 3D-OD157161

Dextran sulfate sodium - MW 3000-6000

CAS : 9011-18-1

Dextran sulfate sodium is a complex carbohydrate that consists of a linear chain of many glucose molecules. It is often used as a gel to protect the bowel during radiation therapy and in the treatment of severe burns. Dextran sulfate sodium can be modified with methylation, click modification, fluorination, saccharide, or glycosylation. Dextran sulfate sodium also has many applications in biochemistry and medicine such as being used as an osmotic agent in cell culture media, after being glycosylated it can be used to treat inflammatory bowel disease. This product is custom synthesized by our company and is available in various sizes from MW 3000-6000.

Degré de pureté : Min. 95%

Couleur et forme : Powder

Ref: 3D-YD176024

Dextran sulfate sodium salt - MW 9,000-16,000

CAS : 9011-18-1

Dextran sulfate sodium salt is a water-soluble polymer that is used as a drug carrier and has many applications in the pharmaceutical industry. It is an oligosaccharide with an average molecular weight of 9,000 to 16,000 Daltons. Dextran sulfate sodium salt can be used for the treatment of cavities, especially those that are infected or in which there is a risk of infection. It can also be used for intubation and has been shown to be effective at reducing allergic reactions by blocking the release of histamine by mast cells. Dextran sulfate sodium salt also has kinetic properties and can be used to study enzymatic reactions. This polymer is not toxic because it cannot be absorbed through the skin or gastrointestinal tract.

Formule : (C₆H₇Na₃O₁₄S₃)n

Ref: 3D-D-0695