CAS 904763-27-5

ATN-161 trifluoroacetate salt

CAS : 904763-27-5

ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.

Formule : C₂₅H₃₆F₃N₉O₁₀S

Degré de pureté : 98% - 99.98%

Couleur et forme : Solid

Masse moléculaire : 711.67

Ref: TM-T10397

ATN-161 trifluoroacetate salt

CAS : 904763-27-5

ATN-161 trifluoroacetate salt

Degré de pureté : ≥95%

Masse moléculaire : 711.67g/mol

Ref: 54-BUP01894

ATN-161 trifluoroacetate salt

CAS : 904763-27-5

ATN-161 is a small molecule that binds to the M2 receptor, which is expressed on macrophages and regulates their function. ATN-161 has been shown to regulate the activation of M2 macrophages in vitro and in vivo. This drug can inhibit the proliferation of human bone marrow-derived macrophages by suppressing the production of IL-1β and IL-6, which are cytokines that induce inflammation. The trifluoroacetate salt formulation of ATN-161 has shown an improved physicochemical stability profile compared with other salts in this class. This means that it will be more stable in aqueous environments, making it suitable for use in coating technologies.
ATN-161 has also been shown to bind to M2 receptors on mouse lung tissue, which may provide a therapeutic advantage for pulmonary diseases such as asthma or chronic obstructive pulmonary disease (COPD).

Formule : C₂₅H₃₆F₃N₉O₁₀S

Degré de pureté : Min. 95%

Masse moléculaire : 711.67 g/mol

Ref: 3D-ELB76327