CAS 90485-25-9

N-[4-(2-Bromoethyl)phenyl]methanesulfonamide

Produit contrôlé

CAS : 90485-25-9

Applications N-[4-(2-Bromoethyl)phenyl]methanesulfonamide is an intermediate in the synthesis of Deoxysotalol (D245550) which is the metabolite of Sotalol (S677300), a potent α-adrenergic receptor antagonist and A class III antiarrythmic. Several studies have examined deoxysotalol on its effects on prostaglandin (PGF2a and 15-methyl PGF2α)-evoked contraction using isolated rat uterus and also in potentiating the contractile effects of Oxytocin (O878500).
References Uloth, et al.: J. Med. Chem., 9, 88 (1966); Narendranath, K.A., et al.: Euro. J. Pharmacol., 46, 15 (1977); Gautam, C.S., et al., Indian. J. Med. Rsch., 76, 107 (1982);

Formule : C₉H₁₂BrNO₂S

Couleur et forme : Neat

Masse moléculaire : 278.17

Ref: TR-B688124