CAS 932973-77-8

VU0514009

CAS : 932973-77-8

VU0514009 is a competitive antagonist of chemokine-like receptor 1 (CMKLR1) with an EC50 of 2 nM. It effectively inhibits chemerin-9-induced arrestin recruitment and receptor internalization, significantly reducing Ca2+ flux responses in HEK293 cells. This compound shows potential for research in inflammatory diseases and metabolic syndrome.

Formule : C₂₁H₂₀ClN₃O₅S₂

Couleur et forme : Solid

Masse moléculaire : 493.98

Ref: TM-T210773