CAS 936481-23-1

(2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine

Produit contrôlé

CAS : 936481-23-1

Applications (2'R)-N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an epimer of N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine (D199035), which is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.
References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014);

Formule : C₃₆H₅₀ClN₃O₁₀S

Couleur et forme : White

Masse moléculaire : 752.31

Ref: TR-D199038