
CAS 93987-29-2
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6 produits concernés.
BI 6015
CAS :Formule :C15H13N3O4SDegré de pureté :97%Couleur et forme :SolidMasse moléculaire :331.34642-Methyl-1-((2-Methyl-5-Nitrophenyl)Sulfonyl)-1H-Benzo[D]Imidazole
CAS :2-Methyl-1-((2-Methyl-5-Nitrophenyl)Sulfonyl)-1H-Benzo[D]ImidazoleDegré de pureté :97%Masse moléculaire :331.35g/molBI-6015
CAS :<p>BI 6015 is an antagonist of HNF4α. HNF4α is a nuclear receptor that regulates gene expression in the intestine cells, liver cells, and pancreas-β cells.</p>Formule :C15H13N3O4SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :331.35BI 6015
CAS :Produit contrôlé<p>Applications BI 6015 is a known HNF4α antagonist that represses the expression of known HNF4α target genes. Studies have shown that BI6015 are also capable of exhibiting selective cytotoxic activities against numerous tumor cell lines.<br>References Kiselyuk. A., et al.: Chem. Biol., 19, 806 (2012);<br></p>Formule :C15H13N3O4SCouleur et forme :NeatMasse moléculaire :331.346HNF4 Antagonist, BI6015
CAS :<p>BI6015 is a fatty acid that inhibits the transcriptional regulation of genes involved in tumorigenesis, cell survival, and drug resistance. It has been shown to inhibit the uptake of glucose and fatty acids by cells. BI6015 also blocks the binding of growth factor-β1 to its receptor, thereby inhibiting signal transduction pathways that regulate cell proliferation and differentiation. BI6015 has been shown to inhibit the activity of enzymes involved in lipid synthesis, which may contribute to its ability to prevent congenital heart disease. This drug has been tested in animal models with promising results but it is not yet known how it will affect human subjects.<br>BI6015 is rapidly absorbed after oral administration and excreted unchanged in urine. The pharmacokinetic properties of this compound have not yet been evaluated in humans.</p>Formule :C15H13N3O4SDegré de pureté :Min. 95%Masse moléculaire :331.35 g/mol




