CAS 96426-21-0

glycine-arginine-glycine-acide aspartique-sérine

Description :

La substance chimique connue sous le nom de "glycine-arginine-glycine-acide aspartique-sérine," avec le numéro CAS 96426-21-0, est un peptide composé de quatre acides aminés : glycine (Gly), arginine (Arg), acide aspartique (Asp) et sérine (Ser). Ce peptide est remarquable pour son rôle dans les processus biologiques, en particulier dans l'adhésion cellulaire et la signalisation. La séquence des acides aminés contribue à ses propriétés structurelles et fonctionnelles, le rendant pertinent dans diverses applications biochimiques, y compris le développement de médicaments et l'ingénierie tissulaire. glycine-arginine-glycine-acide aspartique-sérine peut interagir avec des récepteurs ou des protéines spécifiques, influençant le comportement et les réponses cellulaires. Sa taille relativement petite permet une synthèse et une modification faciles, ce qui est avantageux dans les contextes de recherche et thérapeutiques. De plus, la présence de chaînes latérales chargées et polaires dans les acides aminés peut affecter la solubilité et l'interaction avec d'autres biomolécules. Dans l'ensemble, ce peptide sert de modèle précieux pour étudier les interactions et les fonctions des peptides dans les systèmes biologiques.

Formule : C₁₇H₃₀N₈O₉

InChI : InChI=1/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1

SMILES : C(C[C@@H](C(=NCC(=N[C@@H](CC(=O)O)C(=N[C@@H](CO)C(=O)O)O)O)O)N=C(CN)O)CNC(=N)N

Synonymes :

• H-Gly-Arg-Gly-Asp-Ser-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-serine

H-Gly-Arg-Gly-Asp-Ser-OH

CAS : 96426-21-0

GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation.

Formule : C₁₇H₃₀N₈O₉

Degré de pureté : 96.7%

Couleur et forme : White Lyophilisate

Masse moléculaire : 490.47

Ref: 01-4008998

Gly-Arg-Gly-Asp-Ser

CAS : 96426-21-0

Formule : C₁₇H₃₀N₈O₉

Degré de pureté : 98%

Masse moléculaire : 490.4683

Ref: IN-DA019FVU

Gly-Arg-Gly-Asp-Ser

CAS : 96426-21-0

Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.

Formule : C₁₇H₃₀N₈O₉

Degré de pureté : 98%

Couleur et forme : Solid

Masse moléculaire : 490.47

Ref: TM-TP1459

Gly-Arg-Gly-Asp-Ser

CAS : 96426-21-0

Formule : C₁₇H₃₀N₈O₉

Masse moléculaire : 490.47

Ref: 7W-GL3717

Fibronectin Active Fragment (GRGDS)

CAS : 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

Formule : C₁₇H₃₀N₈O₉CH₃COOHH₂O

Degré de pureté : Min. 95%

Masse moléculaire : 490.47 g/mol

Ref: 3D-PFA-4189

Fibronectin Active Fragment (GRGDS)

CAS : 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials. This product is available as a 0.5mg vial.

Formule : C₁₇H₃₀N₈O₉

Degré de pureté : Min. 95%

Masse moléculaire : 490.47 g/mol

Ref: 3D-PFA-4189-V

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt

CAS : 96426-21-0

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt is a synthetic peptide that is designed to bind to the nuclear factor kappa B (NFκB) and inhibit its activation. NFκB is a transcription factor that regulates gene expression in response to various stimuli, including proinflammatory cytokines, oxidants, and electrophilic compounds. H-Gly-Arg-Gly-Asp-Ser-OH TFA salt has been shown to inhibit NFκB activation in a model system. This molecule also inhibits axonal growth and pluripotent cells differentiation, which may be due to its suppression of the signal peptide. The rate constant for this drug has been measured using polymer compositions and biocompatible polymers.

Formule : C₁₇H₃₀N₈O₉(freebase)

Degré de pureté : Min. 95%

Masse moléculaire : 490.47 g/mol

Ref: 3D-FG108418