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CAS 99294-94-7

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Acétate de tériparatide hydraté

Description :
Acétate de tériparatide hydraté est un peptide synthétique qui imite l'action de l'hormone parathyroïdienne (PTH) et est principalement utilisé dans le traitement de l'ostéoporose. Il se caractérise par sa capacité à stimuler la formation osseuse en favorisant l'activité des ostéoblastes, ce qui le rend particulièrement efficace pour augmenter la densité osseuse et réduire le risque de fractures chez les femmes ménopausées et les individus atteints de certains types d'ostéoporose. La substance est généralement administrée par injection sous-cutanée et est connue pour sa demi-vie relativement courte, nécessitant des doses quotidiennes. Acétate de tériparatide hydraté est une poudre blanche à blanc cassé qui est soluble dans l'eau, et sa formulation comprend de l'acétate comme contre-ion, ce qui aide à stabiliser le peptide. La structure moléculaire du composé est constituée de 34 acides aminés et il est classé comme un médicament biologique en raison de sa nature peptidique. Comme pour tout médicament, il est essentiel de prendre en compte les effets secondaires potentiels, les contre-indications et la nécessité de surveillance pendant le traitement.
Formule :C2H4O2·xH2O·xUnspecified
InChI :InChI=1/C181H291N55O51S2/c1-21-96(18)146(236-160(267)114(48-53-141(250)251)212-174(281)132(84-239)232-177(284)143(93(12)13)233-147(254)103(185)82-237)178(285)216-111(45-50-134(187)241)155(262)219-119(65-90(6)7)163(270)213-116(55-62-289-20)158(265)224-124(71-100-79-196-86-203-100)167(274)226-126(73-135(188)242)169(276)217-117(63-88(2)3)148(255)201-81-138(245)205-105(39-27-30-56-182)149(256)223-123(70-99-78-195-85-202-99)166(273)221-121(67-92(10)11)164(271)225-128(75-137(190)244)171(278)231-131(83-238)173(280)214-115(54-61-288-19)157(264)210-112(46-51-139(246)247)153(260)208-109(43-34-60-199-181(193)194)159(266)234-144(94(14)15)175(282)215-113(47-52-140(248)249)156(263)222-122(69-98-77-200-104-38-26-25-37-102(98)104)165(272)220-120(66-91(8)9)161(268)209-108(42-33-59-198-180(191)192)151(258)206-106(40-28-31-57-183)150(257)207-107(41-29-32-58-184)152(259)218-118(64-89(4)5)162(269)211-110(44-49-133(186)240)154(261)228-129(76-142(252)253)172(279)235-145(95(16)17)176(283)229-125(72-101-80-197-87-204-101)168(275)227-127(74-136(189)243)170(277)230-130(179(286)287)68-97-35-23-22-24-36-97/h22-26,35-38,77-80,85-96,103,105-132,143-146,200,237-239H,21,27-34,39-76,81-84,182-185H2,1-20H3,(H2,186,240)(H2,187,241)(H2,188,242)(H2,189,243)(H2,190,244)(H,195,202)(H,196,203)(H,197,204)(H,201,255)(H,205,245)(H,206,258)(H,207,257)(H,208,260)(H,209,268)(H,210,264)(H,211,269)(H,212,281)(H,213,270)(H,214,280)(H,215,282)(H,216,285)(H,217,276)(H,218,259)(H,219,262)(H,220,272)(H,221,273)(H,222,263)(H,223,256)(H,224,265)(H,225,271)(H,226,274)(H,227,275)(H,228,261)(H,229,283)(H,230,277)(H,231,278)(H,232,284)(H,233,254)(H,234,266)(H,235,279)(H,236,267)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,286,287)(H4,191,192,198)(H4,193,194,199)
SMILES :CCC(C)C(C(=NC(CCC(=N)O)C(=NC(CC(C)C)C(=NC(CCSC)C(=NC(Cc1cnc[nH]1)C(=NC(CC(=N)O)C(=NC(CC(C)C)C(=NCC(=NC(CCCCN)C(=NC(Cc1cnc[nH]1)C(=NC(CC(C)C)C(=NC(CC(=N)O)C(=NC(CO)C(=NC(CCSC)C(=NC(CCC(=O)O)C(=NC(CCCNC(=N)N)C(=NC(C(C)C)C(=NC(CCC(=O)O)C(=NC(Cc1c[nH]c2ccccc12)C(=NC(CC(C)C)C(=NC(CCCNC(=N)N)C(=NC(CCCCN)C(=NC(CCCCN)C(=NC(CC(C)C)C(=NC(CCC(=N)O)C(=NC(CC(=O)O)C(=NC(C(C)C)C(=NC(Cc1cnc[nH]1)C(=NC(CC(=N)O)C(=NC(Cc1ccccc1)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C(C(CCC(=O)O)N=C(C(CO)N=C(C(C(C)C)N=C(C(CO)N)O)O)O)O
Synonymes :
  • <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-leucylglycyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-tryptophyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-α-aspartyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-asparaginyl-, acetate (salt), hydrate
  • <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-leucylglycyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-tryptophyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-α-aspartyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-asparaginyl-, acetate, hydrate (1:?:?)
  • Forteo
  • L-Phenylalanine, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt)
  • L-Phenylalanine, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt) hydrate
  • L-Seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-L-phenylalanine acetate (salt) hydrate
  • Parathar
  • Parathar acetate
  • Teribone
  • Teriparatide Acetate
  • Voir plus de synonymes
Trier par
Degré de pureté (%)
0
100
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0
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50
|
90
|
95
|
100
2 produits concernés.