Substrats fluorogènes
Dans cette catégorie, vous trouverez une sélection complète de substrats fluorogènes conçus pour la catalyse enzymatique. Ces substrats sont utilisés avec divers types d'enzymes et sont capables de produire de la couleur et de la fluorescence lors de la réaction. Les substrats fluorogènes sont des outils essentiels dans la recherche en biochimie et biologie moléculaire, permettant la détection et la quantification de l'activité enzymatique avec une grande sensibilité et spécificité. Ils sont largement utilisés dans les essais pour étudier la cinétique enzymatique, rechercher des inhibiteurs d'enzymes et surveiller les processus cellulaires. Chez CymitQuimica, nous proposons des substrats fluorogènes de haute qualité pour soutenir vos recherches, garantissant des résultats fiables et précis dans vos essais enzymatiques.
297 produits trouvés pour "Substrats fluorogènes"
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Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride
CAS :Glycyl-glycine 7-amido-4-methylcoumarin hydrochloride is a synthetic peptide substrate used as a fluorogenic substrate for aminopeptidase.Formule :C14H16ClN3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :325.75 g/mol4-Methylumbelliferyl b-D-galactopyranoside-6-sulphate sodium salt - Moscerdam™ biochemical purity
CAS :4-MU-Gal-6S (M4A) is a fluorogenic substrate of galactose-6-sulfate sulfatase (GALNS), used for the diagnosis of Mucopolysaccharidosis IV type A (MPS IV A). MPS IV, also known as Morquio syndrome, is a rare metabolic disorder in which the human body cannot process glycosaminoglycans (GAGs). MPS IV A is caused by the deficiency of the enzyme N-acetyl-galactosamine-6-sulfatase resulting in accumulation of keratan and chondroitin sulfate in tissues. M4A is used as the GALNS substrate in the anti-lysosomal enzyme antibody assay for the treatments of lysosomal storage disorders (LSDs) with enzyme replacement therapies (ERTs).Formule :C16H17NaO11SDegré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :440.36 g/mol4-Methylumbelliferyl oleate
CAS :Methylumbelliferyl oleate is a MOSCERDAM® substrate targeting the lipase enzymeFormule :C28H40O4Degré de pureté :Min. 90 Area-%Couleur et forme :White PowderMasse moléculaire :440.61 g/mol4-Methylumbelliferyl heptanoate
CAS :Lipase targeting MOSCERDAM® substrateFormule :C17H20O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :288.34 g/molDDAO galactoside
CAS :The DDAO molecule [7-hydroxy-9H-(1, 3-dichloro-9, 9 dimethylacridin-2-one] is used as a stain and a dye in molecular biology, due to its ability to bind intracellular and extracellular DNA. DDAO galactoside is a fluorogenic substrate for galactosidase.
Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :470.3 g/mol4-Methylumbelliferyl b-D-ribofuranoside
CAS :The 4-Methylumbelliferyl b-D-ribofuranoside is a top-notch fluorogenic substrate for glycosidase activity detection. Upon hydrolysis by enzymes, it generates a strongly fluorescent 4-methylumbelliferone molecule, enabling rapid assay results and real-time monitoring of enzymatic reactions. This product is suitable for many biological research applications, such as in vitro analysis, diagnostic testing, and drug discovery. With its high sensitivity and specificity, it delivers consistent and accurate results, making it an essential tool for scientists and researchers.Formule :C15H16O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :308.28 g/mol4-Methylumbelliferyl phosphate bis(cyclohexylammonium) salt
CAS :Sensitive fluorogenic substrate for fluorometric and UV-spectrophotometric assays of phosphatases. This may also be used for in-gel assaysFormule :C22H35N2O6PDegré de pureté :Min 99%Couleur et forme :White to off-white solid.Masse moléculaire :454.50 g/molMonofluoresceinated mannitol
Monofluoresceinated mannitol is a fluorescently labeled form of mannitol. It is used as a tracer for metabolism studies.Formule :C27H24O12Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :540.46 g/molAc-Abu-Tle-Leu-Gln-AMC TFA salt
A fluorogenic substrate for detection of enzymatic activity of the SARS-CoV-2 Mpro protease. The fluorophore 7-Amino-4-methylcoumarin (AMC) is linked to the tetrapeptide via a peptide bond at the C-terminal of the glutamine residue. Following the hydrolytic activity of the Mpro protease, the fluorogenic AMC group get released from the substrate, generating a fluorescent signal (Ex 380 nm / Em 455 nm).Formule :C33H48N6O8(freebase)Degré de pureté :Min. 95.0 Area-%Masse moléculaire :656.77 g/molL-Lysyl-L-alanine 7-amido-4-methylcoumarin dihydrochloride
CAS :L-Lysyl-L-alanine 7-amido-4-methylcoumarin dihydrochloride is a fluorogenic peptide substrate for aminopeptidase. This AMC peptide substrate is normally used to rapidly profile the N-terminal specificity of proteases.Degré de pureté :Min. 98.0 Area-%Couleur et forme :Powder4-Methylumbelliferyl beta-D-lactoside
CAS :Fluorogenic substrate for beta-galactosidaseFormule :C22H28O13Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :500.45 g/mol4-(Trifluoromethyl)umbelliferyl-β-D-cellotrioside
CAS :4-(Trifluoromethyl)umbelliferyl-beta-D-cellotrioside is a fluorogenic substrate for cellulase. After cleavage, the fluorophore 4-(trifluoromethyl)umbelliferone, commonly referred as TFMU, is released, exhibiting a blueish color. 4-(Trifluoromethyl)umbelliferyl-beta-D-cellotrioside is used to study the enzyme kinetics in bacterial cellulose degradation assays as well as in biomass conversion research studies.Formule :C28H35F3O18Degré de pureté :Min. 95%Couleur et forme :White to off-white solid.Masse moléculaire :716.56 g/molL-Alanine-7-amido-4-methylcoumarin hydrochloride
CAS :L-Alanine-7-amido-4-methylcoumarin hydrochloride is a synthetic peptide substrate used as a fluorogenic substrate for alanine aminopeptidase.Formule :C13H14N2O3·HClDegré de pureté :Min. 90%Couleur et forme :PowderMasse moléculaire :282.72 g/mol4-Methylumbelliferyl 2-deoxy-2-sulfamino-b-D-glucopyranoside sodium salt
4-Methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium salt is a fluorogenic substrate for N-sulfoglucosamine sulfohydrolase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-deoxy-2-sulfamino-beta-D-glucopyranoside sodium saltas a substrate for measuring the N-sulfoglucosamine sulfohydrolase activity is used for screening of Mucopolysaccharidosis IIIA (MPS IIIA) and diagnosis of Sanfilippo A syndrome.Formule :C16H19NO10SNaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :439.37 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-α-D-glucopyranoside-6-sulfate potassium
CAS :4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside-6-sulfate potassium is a fluorogenic substrate for N-acetylglucosamine-6-sulfatase. After enzymatic cleaveage, free 4-methylumbelliferone (also known as hymecromone) is released, exhibiting blue fluorescence upon excitation with UV light. The strongest fluorescence of 4-methylumbelliferone requires deprotonation of the hydroxyl group (thus requires alkaline pH), with a maximal fluorescence intensity obtained with excitation at 350 to 370 nm and emission at 440 to 470 nm. The use of 4-methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside-6-sulfate potassiumas a substrate for measuring the N-acetylglucosamine-6-sulfatase activity is used for screening of Mucopolysaccharidosis IIID (MPS IIID) (a rare lysosomal storage disorder) and Sanfilippo D syndrome diagnosis.Formule :C18H20KNO11SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :497.52 g/mol5-Dodecanoylaminofluorescein di-b-D-galactopyranoside
CAS :5-Dodecanoylaminofluorescein di-b-D-galactopyranoside, commonly known as C12FDG, is a fluorogenic substrate for β-galactosidase. Fluorescein is released upon enzymatic cleavage by β-galactosidase. The intensity of its fluorescence is utilised to quantify β-galactosidase activity. C12FDG has been shown to be useful in identifying senescent cells that are associated with aging and cancer. It has also been used as a model system in some studies for studying disease activity, intracellular targets, and biological sample storage. It is also used to identify cancer tissues and radiation damage in the form of senescent cells. The chemical structure of 5DAFG is similar to that of the natural sugar galactose. 5DAFG binds to the plasma membrane of cells due to its lipophilic properties and then enters the cell through transport proteins on the cell surface called ATP binding cassette transporters.Formule :C44H55NO16Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :853.9 g/molFluorescein mono-b-D-galactopyranoside
CAS :Fluorescein mono-b-D-galactopyranoside or FMG is a fluorogenic substrate for beta-galactosidase. The fluorophore fluorescein is released after enzymatic cleavage, exhibiting a greenish fluorescent. This substrate is particularly valuable in gene expression studies (e.g., lacZ reporter assays) and as a probe for cell-based assays for real-time monitoring.Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :494.45 g/mol4-Methylumbelliferyl 2-acetamido-2-deoxy-b-D-glucopyranoside-6-sulfate sodium salt
CAS :4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt is a high-quality fluorogenic substrate specifically designed for the detection and quantification of various enzymes, including beta-glucosidases and sulfatases. Upon hydrolysis by the target enzyme, this substrate releases the highly fluorescent 4-methylumbelliferone, allowing for real-time monitoring and accurate measurement of enzyme activities in biochemical assays, diagnostic tests, and research applications. 4-Methylumbelliferyl 2-acetamido-2-deoxy-beta-D-glucopyranoside-6-sulfate sodium salt has excellent solubility in water, ensuring a consistent and reliable performance in different experimental conditions. This versatile substrate is an essential tool for researchers and industry professionals who require a sensitive and reproducible detection method for enzymes of interest.Formule :C18H20NO11SNaDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :481.41 g/molAcetyl-L-alanine 7-amido-4-methylcoumarin
CAS :Acetyl-L-alanine 7-amido-4-methylcoumarin is a fluorogenic substrate for aminopeptidase. The enzyme cleaves the N-terminal amino acids, yielding a blue fluorescent solution.
Formule :C15H16N2O4Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :288.3 g/mol6-Hexadecanoylamino-4-methylumbelliferyl phosphorylcholine - Moscerdam™ biochemical purity
CAS :6-Hexadecanoylamino-4-methylumbelliferyl phosphorylcholine (HMUPC) is a fluorogenic substrate of acid sphingomyelinase (ASM) in the application of the diagnosis of Niemann–Pick type A and B (NPAB). NPAB is one of the lysosomal storage diseases, caused by a deficiency of ASM. This deficiency results in the accumulation of sphingomyelin and other lipids in various tissues. The assay using HMUPC as the substrate shows rapid and robust determination of ASM activity. When combined with the unlabelled natural substrate such as sphingomyelin as a specific inhibitor of ASM activity, the specificity of assay is enhanced up to the level of the classical assay with radiolabelled natural substrate. HMUPC is also used as the substrate in the ASM assay to investigate the retention of lysosomal enzyme activity of bi-functional IgG-ASM fusion protein in the delivery across blood-brain barrier.
Formule :C31H51N2O7PDegré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :594.72 g/mol
