Canal ionique
Les canaux ioniques sont des protéines spécialisées qui forment des pores dans les membranes cellulaires, permettant le passage sélectif d'ions tels que le sodium, le potassium, le calcium et le chlorure. Ces canaux jouent un rôle crucial dans divers processus physiologiques, y compris la transmission de l'influx nerveux, la contraction musculaire et la régulation de l'homéostasie cellulaire. Les canaux ioniques sont des cibles essentielles dans la découverte de médicaments, en particulier pour le traitement des troubles neurologiques, des maladies cardiovasculaires et de la gestion de la douleur. Chez CymitQuimica, nous proposons une large gamme de protéines de canaux ioniques de haute qualité et de réactifs associés pour soutenir vos projets de recherche et de développement de médicaments.
107 produits trouvés pour "Canal ionique"
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Nicorandil - Bio-X ™
CAS :<p>Nicorandil is an ATP-dependent potassium channel activator. It activates mitochondrial ATP-dependent potassium (KATP) channels and inhibits the TLR4/MyD88/NF-κB/NLRP3 pathway, which reduces myocardial infarction-induced pyroptosis. Pyroptosis is an inflammatory cell death process that regulates cardiomyocyte loss after myocardial infarction. These findings suggest that nicorandil may be a potential therapy for ischemic heart disease due to its cardioprotective effects.</p>Formule :C8H9N3O4Degré de pureté :(%) Min. 95%Couleur et forme :PowderMasse moléculaire :211.17 g/molBarnidipine hydrochloride
CAS :<p>Calcium channel blocker</p>Formule :C27H30ClN3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :528 g/molVarenicline tartrate
CAS :<p>Partial agonist of α4β2 nicotinic receptors; acetylcholine receptor α7 agonist</p>Formule :C13H13N3·C4H6O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :361.35 g/molFelodipine - Bio-X ™
CAS :<p>Felodipine is a calcium channel blocker and a member of the 1,4-dihydropyridine class of calcium channel blockers that is used to treat high blood pressure and related conditions. Felodipine increases the level of natriuretic peptide in the blood and reduces levels of infectious diseases such as influenza A virus and respiratory syncytial virus (RSV).<br>Felodipine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Formule :C18H19Cl2NO4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :384.25 g/molAloe-emodin - Bio-X ™
CAS :<p>Aloe-emodin is an anthraquinone derivative that is found in the aloe plant. It has a strong stimulant laxative action. Aloe-emodin may be useful in the treatment of cancer, as it inhibits cell proliferation by inducing apoptosis.</p>Formule :C15H10O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :270.24 g/molPiracetam - Bio-X ™
CAS :Produit contrôlé<p>Piracetam is a nootropic drug that is used for the treatment of sickle cell disease, alcohol dependence and as a cognitive enhancer. This drug is a cyclic derivative of GABA and has neuroprotective and anticonvulsant properties. Piracetam has been said to improve neuronal plasticity.</p>Formule :C6H10N2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :142.16 g/molKainic acid monohydrate
CAS :<p>Agonist of kainate receptors, a subclass of ionotropic glutamate receptors with neuroexcitatory action. At high concentrations, it can induce seizures and act as neurotoxin, causing neuron death due to overstimulation.</p>Formule :C10H15NO4·H2ODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :231.25 g/molAmbroxol HCl - Bio-X ™
CAS :<p>Ambroxol is a secretolytic agent that is used in the treatment of respiratory diseases and chronic coughs. Ambroxol has been shown to inhibit the NO-dependent activation of soluble guanylate cyclase so that the airway is not inflamed or its functions are not disturbed. Also, excessive mucus secretion is suppressed which as a result lowers the phlegm viscosity.</p>Formule :C13H18Br2N2O•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :414.56 g/molCilnidipine - Bio-X ™
CAS :<p>Clinidipine is a dihydropyridine calcium channel blocker that is used to treat hypertension. This drug acts on L-type calcium channels of blood vessels by blocking calcium and suppressing the contraction of blood vessels, thereby reducing blood pressure. . Cilnidipine also shows activity against N-type calcium channels.</p>Formule :C27H28N2O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :492.52 g/molNifedipine - Bio-X ™
CAS :<p>Nifedipine is a dihydropyridine calcium channel blocker that is used to manage several subtypes of angina pectoris and hypertension. This drug blocks L-type voltage gated calcium channels in order for blood pressure to be reduced and an increase in oxygen supply to the heart.</p>Formule :C17H18N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :346.33 g/molLamotrigine - Bio-X ™
CAS :Produit contrôlé<p>Lamotrigine is an antiepileptic phenyltriazine drug that is used to treat epilepsy and as a mood stabilizer in bipolar disorder. Although, this drug’s action is not fully well understood it is similar to carbamazepine which involves inhibiting voltage-sensitive sodium channels. Lamotrigine blocks voltage-sensitive sodium channels, which reduces neuronal excitability by blocking action potentials.</p>Formule :C9H7Cl2N5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :256.09 g/molPF 06372865
CAS :<p>Positive allosteric modulator of GABA(A) receptor</p>Formule :C22H21FN4O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :440.49 g/molAmantadine hydrochloride - Bio-X ™
CAS :Produit contrôlé<p>Amantadine is an antiviral drug that is used to treat dyskinesia in patients with Parkinson’s disease. This drug’s mechanism is not fully understood however it is said to aid in releasing dopamine from the nerve ending in brain cells. Amantadine is also an NDMA antagonist.</p>Formule :C10H17N•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :187.71 g/molIsradipine
CAS :<p>L-type calcium channel blocker</p>Formule :C19H21N3O5Degré de pureté :Min. 95%Couleur et forme :Yellow PowderMasse moléculaire :371.39 g/molIcilin - Bio-X ™
CAS :<p>Icilin is a transient receptor potential M8 (TRPM8) agonist drug that is used for the treatment of pruritis. This drug has shown to be effective in producing an extreme cold sensation in both human and animal models. It is used in research for studying TRP channels.</p>Formule :C16H13N3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :311.29 g/molPrilocaine HCl - Bio-X ™
CAS :<p>Prilocaine is a drug used as a local anaesthetic in dental procedures. It has been shown to reduce the incidence of pain caused. This drug is also a sodium channel blocker that blocks the influx of sodium into cells.</p>Formule :C13H20N2O•HClDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :256.77 g/molRepaglinide - Bio-X ™
CAS :<p>Repaglinide is an antihyperglycemic drug that is used for the improvement of glycemic control in diabetes. This drug acts on the beta cells of the pancreas and binds to specific receptors on the beta cells known as ATP-sensitive potassium channels. As a result, this promotes insulin secretion from beta cells.</p>Formule :C27H36N2O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :452.59 g/molVinpocetin - Bio-X ™
CAS :<p>Vinpocetin or Vinpocetine is a synthetic derivative of a vinca alkaloid that is used to treat symptoms of cerebrovascular diseases such as stroke and dementia. It blocks sodium channels, reduces cellular calcium influx and has shown to have antioxidant activity. Studies have also suggested that vinpocetin can inhibit phosphodiesterase- 1 (PDE-1) in isolated rabbit aorta.</p>Formule :C22H26N2O2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :350.45 g/molMinoxidil - Bio-X ™
CAS :<p>Minoxidil is an antihypertensive agent used for the treatment of resistant hypertension that has caused organ damage. This drug has vasodilatory properties and promotes the survival of human dermal papillary cells. Therefore, this drug is also used to treat alopecia.</p>Formule :C9H15N5ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :209.25 g/molRiluzole - Bio-X ™
CAS :<p>Riluzole is a glutamate antagonist that is used for the treatment of amyotrophic lateral sclerosis. This drug is also used as an anticonvulsant. Although a complete mechanism of action is unknown, it has an inhibitory effect on glutamate release and it inactivates voltage dependent sodium channels.</p>Formule :C8H5F3N2OSDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :234.2 g/mol
