EGFR
Les inhibiteurs du récepteur du facteur de croissance épidermique (EGFR) sont des composés qui bloquent la signalisation de l'EGFR, un récepteur souvent surexprimé dans divers cancers et qui joue un rôle crucial dans l'angiogenèse. Les inhibiteurs de l'EGFR sont utilisés pour prévenir la croissance tumorale et les métastases en perturbant les voies qui favorisent la formation de vaisseaux sanguins dans les tumeurs. Ces inhibiteurs sont largement utilisés dans la recherche et le traitement du cancer. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de l'EGFR de haute qualité pour soutenir vos recherches en oncologie et angiogenèse.
587 produits trouvés pour "EGFR"
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Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245)
Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) is an antibody targeting Phospho-EGFR (Tyr1068). Anti-Phospho-EGFR (Tyr1068) Antibody (3Q245) can be used in ELISA, WB.Couleur et forme :Odour LiquidAnti-EGFR Antibody (7X976)
Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.Couleur et forme :Odour LiquidAnti-Phospho-EGFR (Tyr1092) Antibody (9I899)
Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) is an antibody targeting Phospho-EGFR (Tyr1092). Anti-Phospho-EGFR (Tyr1092) Antibody (9I899) can be used in ELISA, WB.Couleur et forme :Odour LiquidAnti-EGFR Antibody (3B845)
Anti-EGFR Antibody (3B845) is an antibody targeting EGFR. Anti-EGFR Antibody (3B845) can be used in ELISA, WB, IHC.Couleur et forme :Odour LiquidAnti-EGFR Antibody (9S619)
Anti-EGFR Antibody (9S619) is an antibody targeting EGFR. Anti-EGFR Antibody (9S619) can be used in ELISA, IHC, FCM.Couleur et forme :Odour LiquidBI-4142
CAS :BI-4142 is a HER2 inhibitor that inhibits cancer cell proliferation, suppresses her2-dependent cell lines and inhibits downstream signalling.Formule :C28H27N9O2Degré de pureté :97.21% - 98.09%Couleur et forme :SolidMasse moléculaire :521.57Ref: TM-T63643
1mg57,00€5mg120,00€1mL*10mM (DMSO)138,00€10mg177,00€25mg356,00€50mg537,00€100mg803,00€200mg1.341,00€AEE 788
CAS :Formule :C27H32N6Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :440.60Tucatinib hemiethanolate
CAS :Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM.Formule :C54H54N16O5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :1007.11Tyrphostin AG 1478
CAS :Formule :C16H14ClN3O2Degré de pureté :>98.0%(HPLC)Couleur et forme :Light orange to Yellow to Green powder to crystalMasse moléculaire :315.76Rociletinib hydrobromide
CAS :Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).Formule :C27H29BrF3N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :636.46CL-387785
CAS :Formule :C18H13BrN4ODegré de pureté :>98.0%(GC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :381.23(3S,4S)-PF-06459988
CAS :(3S, 4S)-PF-06459988, a less active S enantiomer, specifically inhibits T790M mutant EGFR with high selectivity.Formule :C19H22ClN7O3Couleur et forme :SolidMasse moléculaire :431.88Erlotinib-d6
CAS :Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib D6 is a deuterium labeled Erlotinib .Formule :C22H23N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :399.47PD 158780
CAS :Formule :C14H12BrN5Degré de pureté :>97.0%(HPLC)Couleur et forme :White to Yellow to Green powder to crystalMasse moléculaire :330.19Neratinib maleate
CAS :Neratinib maleate is a selective HER2/EGFR inhibitor (IC50: 59/92 nM) used in breast and prostate cancer studies.Formule :C34H33ClN6O7Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :673.11Tyrphostin AG 490
CAS :Formule :C17H14N2O3Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :294.31Mubritinib
CAS :Formule :C25H23F3N4O2Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Gray to Brown powder to crystalMasse moléculaire :468.48Tyrphostin AG 879
CAS :Formule :C18H24N2OSDegré de pureté :>98.0%(HPLC)Couleur et forme :Light yellow to Yellow to Orange powder to crystalMasse moléculaire :316.46BMS-599626
CAS :Formule :C27H27FN8O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light orange powder to crystalMasse moléculaire :530.56Trichilinin D
CAS :Trichilinin D is a natural product that can be used in related research in the field of life sciences. Its product number is TN8637.Formule :C37H44O8Masse moléculaire :616.74Flurandrenolide
CAS :Flurandrenolide is a corticosteroid with anti-inflammatory effects that activates EGFR (EC50=23 nM).Formule :C24H33FO6Couleur et forme :Crystals From Acetone + Hexane SolidMasse moléculaire :436.51GW2974
CAS :GW2974, Oral EGFR/ErbB2 dual inhibitor, inhibits glioblastoma multiforme (GBM) cell invasion and tumor growth.Formule :C23H21N7Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :395.46Erlotinib
CAS :Formule :C22H23N3O4Degré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :393.44Tyrphostin 8
CAS :Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits proteinFormule :C10H6N2ODegré de pureté :97%Couleur et forme :SolidMasse moléculaire :170.17WHI-P154
CAS :Formule :C16H14BrN3O3Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Yellow to Orange powder to crystalMasse moléculaire :376.21Osimertinib dimesylate
CAS :Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).Formule :C30H41N7O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :691.82Mavelertinib
CAS :Mavelertinib (PF-06747775) is an EGFR tyrosine kinase (EGFR TKI) inhibitor that inhibits T790M/L858R and can be used to study tumours.Formule :C18H22FN9O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :415.42AV-412 free base
CAS :AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR(T790M), EGFR(L858R), EGFR(L858R/T790M) and ErbB2).Formule :C27H28ClFN6OCouleur et forme :SolidMasse moléculaire :507Vandetanib
CAS :Formule :C22H24BrFN4O2Degré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :475.36Canertinib
CAS :Formule :C24H25ClFN5O3Degré de pureté :>98.0%(HPLC)(qNMR)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :485.94EGFR vIII Protein, Human, Recombinant (His)
EGFR vIII Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Couleur et forme :Lyophilized PowderMasse moléculaire :61-75 Kda (reducing condition)Ref: TM-TMPJ-00648
5µg90,00€10µg130,00€20µg193,00€50µg381,00€100µg600,00€200µg947,00€500µg1.765,00€1mg2.535,00€EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :60-90 KDa (reducing condition)EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted)Ref: TM-TMPK-00689
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€EGFR Protein, Human, Recombinant (His & Avi)
EGFR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :71.5 kDa (predicted). Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.AG 1478 Hydrochloride
CAS :Formule :C16H14ClN3O2·HClDegré de pureté :>95.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :352.22EGFR Protein, Human, Recombinant (His & Avi), Biotinylated
EGFR Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-120 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00427
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled
EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :71.5 kDa (predicted). Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00425
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00690
5µg150,00€10µg242,00€20µg405,00€50µg794,00€100µg1.343,00€200µg1.978,00€500µg3.455,00€EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification.Couleur et forme :Lyophilized PowderMasse moléculaire :41.6 kDa (predicted). Due to glycosylation, the protein migrates to 60-78 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00692
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€EGFR Protein, Rhesus macaque, Recombinant (His)
EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :69.8 kDa (predicted). Due to glycosylation, the protein migrates to 85-100 kDa based on Tris-Bis PAGE result.Lapatinib Ditosylate
CAS :Formule :C29H26ClFN4O4S·2C7H8O3SDegré de pureté :>98.0%(T)(HPLC)Couleur et forme :White to Light yellow powder to crystalMasse moléculaire :925.46Anti-EGFR Monoclonal Antibody
Antibody Type: Rabbit Monoclonal
Application: FCM
Reactivity: HumanDegré de pureté :> 95% as determined by SDS-PAGE.Couleur et forme :LiquidMasse moléculaire :150 kDaAnti-EGFR Monoclonal Antibody-Biotin
Antibody Type: Rabbit Monoclonal
Application: FCM
Reactivity: HumanDegré de pureté :> 95% as determined by SDS-PAGE.Couleur et forme :LiquidMasse moléculaire :150 kDaE-4031 dihydrochloride
CAS :E-4031 dihydrochloride is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM)Formule :C21H29Cl2N3O3SDegré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :474.44ZM39923 hydrochloride
CAS :ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor, almost no activity to JAK2 and modestly potent to EGFR; also is sensitive to transglutaminase.Formule :C23H25NO·HClDegré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :367.91Tesevatinib
CAS :Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C24H25Cl2FN4O2Degré de pureté :97.89% - 98.66%Couleur et forme :SolidMasse moléculaire :491.39EBE-A22
CAS :EBE-A22 (PD153035 Analog 63) is a derivative of PD 153035 which can inhibit ErbB-1-phosphorylation, whereas EBE-A22 is inactive.Formule :C17H16BrN3O2Degré de pureté :99.087% - 99.88%Couleur et forme :SolidMasse moléculaire :374.23Derazantinib dihydrochloride
CAS :Derazantinib, a multi-kinase inhibitor targeting FGFR, benefits FGFR2-positive iCCA; its dihydrochloride form is a salt variant.Formule :C29H31Cl2FN4OCouleur et forme :SolidMasse moléculaire :541.49Tyrphostin A1
CAS :Tyrphostin A1 (Tyrphostin 1) is an inhibitor of EGFR tyrosine kinase .Formule :C11H8N2ODegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :184.19TAS0728
CAS :TAS0728 is a HER2 inhibitor, with antitumor activityFormule :C26H32N8O3Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :504.58Ref: TM-T7819
1mg48,00€5mg105,00€1mL*10mM (DMSO)111,00€10mg166,00€25mg304,00€50mg485,00€100mg658,00€200mg888,00€WZ4002
CAS :WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.Formule :C25H27ClN6O3Degré de pureté :97.51%Couleur et forme :SolidMasse moléculaire :494.97Ref: TM-T6238
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg111,00€50mg177,00€100mg313,00€200mg464,00€Cyasterone
CAS :Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65WZ8040
CAS :WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).Formule :C24H25ClN6OSDegré de pureté :97.42% - 99.785%Couleur et forme :SolidMasse moléculaire :481.01Olmutinib
CAS :Olmutinib is an oral mutant-specific EGFR inhibitor for cancer treatment with potential lower toxicity.Formule :C26H26N6O2SDegré de pureté :99.14% - 99.63%Couleur et forme :SolidMasse moléculaire :486.59Ref: TM-T6918
2mg37,00€5mg54,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg130,00€50mg170,00€100mg268,00€200mg437,00€MAZ51
CAS :MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Formule :C21H18N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :314.38ONO-7475
CAS :ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinaseFormule :C32H26N4O6Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :562.57Gefitinib-based PROTAC 3
CAS :Gefitinib-PROTAC 3 degrades EGFR in cancer cells; DC50s: 11.7 nM (HCC827) and 22.3 nM (H3255).Formule :C47H57ClFN7O8SDegré de pureté :97.29% - 98.25%Couleur et forme :SolidMasse moléculaire :934.51Butein
CAS :Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.Formule :C15H12O5Degré de pureté :98.76% - >99.99%Couleur et forme :SolidMasse moléculaire :272.25Ref: TM-T6427
1mg40,00€2mg52,00€1mL*10mM (DMSO)82,00€5mg84,00€10mg101,00€25mg202,00€50mg326,00€100mg520,00€Dacomitinib hydrate
CAS :Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family ofFormule :C24H27ClFN5O3Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :487.96Ref: TM-T19965
5mg48,00€1mL*10mM (DMSO)57,00€10mg75,00€25mg100,00€50mg133,00€100mg200,00€200mg295,00€Sapitinib
CAS :Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib orFormule :C23H25ClFN5O3Degré de pureté :98.89% - 99.83%Couleur et forme :SolidMasse moléculaire :473.93CNX-2006
CAS :CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.Formule :C26H27F4N7O2Degré de pureté :98.85% - 99.16%Couleur et forme :SolidMasse moléculaire :545.53AZD8931 diFuMaric acid
CAS :AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).Formule :C31H33ClFN5O11Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :706.1Ref: TM-T8751
1mg58,00€5mg118,00€1mL*10mM (DMSO)170,00€10mg172,00€25mg281,00€50mg396,00€100mg537,00€200mg712,00€Almonertinib
CAS :Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.Formule :C30H35N7O2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :525.64Ref: TM-T5462
1mg94,00€5mg187,00€1mL*10mM (DMSO)235,00€10mg295,00€25mg497,00€50mg717,00€100mg982,00€500mg1.998,00€CZC-8004
CAS :CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
Formule :C17H16FN5Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :309.34PD158780
CAS :PD 158780 blocks all ErbB receptors: EGFR, ErbB2-4, with IC50s: 8μM, 49-52 nM.Formule :C14H12BrN5Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :330.18Ref: TM-T5410
1mg38,00€5mg80,00€1mL*10mM (DMSO)93,00€10mg113,00€25mg205,00€50mg358,00€100mg523,00€200mg750,00€WZ-3146
CAS :WZ3146: EGFR(L858R/E746_A750) inhibitor, IC50=2 nM, selective, doesn't block ERBB2(T798I).Formule :C24H25ClN6O2Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :464.95Ref: TM-T6733
1mg50,00€2mg71,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg170,00€25mg301,00€50mg484,00€100mg692,00€β-Hydroxyisovalerylshikonin
CAS :Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFormule :C21H24O7Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :388.41Pelitinib
CAS :Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Formule :C24H23ClFN5O2Degré de pureté :98.37% - 99.84%Couleur et forme :Off-White SolidMasse moléculaire :467.92AG 1406
CAS :AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.Formule :C16H18N2ODegré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :254.33Tyrphostin AG 528
CAS :Tyrphostin AG 528 (Tyrphostin B66) is an inhibitor of EGFR (IC50: 4.9 μM) and ErbB2 (IC50: 2.1 μM).Formule :C18H14N2O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :306.32CP-724714
CAS :CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2
Formule :C27H27N5O3Degré de pureté :97.1% - 98.82%Couleur et forme :SolidMasse moléculaire :469.54TAS6417
CAS :Zipalertinib (TAS6417, CLN-081) is a novel, highly potent, orally active covalent EGFR tyrosine kinase inhibitor.Cost-effective and quality-assured.Formule :C23H20N6ODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T16996
1mg93,00€2mg117,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg595,00€50mg795,00€100mg1.071,00€200mg1.468,00€WS6
CAS :WS6, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Formule :C29H31F3N6O3Degré de pureté :97.65% - 99.95%Couleur et forme :SolidMasse moléculaire :568.59PD153035 hydrochloride
CAS :PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR; few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
Formule :C16H15BrClN3O2Degré de pureté :99.39% - ≥95%Couleur et forme :SolidMasse moléculaire :396.67WHI-P154
CAS :WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.Formule :C16H14BrN3O3Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :376.2Trastuzumab
CAS :Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2.Degré de pureté :97.1% (SDS-PAGE); 99.2% (SEC-HPLC) - SDS-PAGE: 97.1%；SEC-HPLC: 99.2%Couleur et forme :LiquidMasse moléculaire :145.36 kDaAG1557
CAS :AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).
Formule :C16H14IN3O2Degré de pureté :98.61% - 99.23%Couleur et forme :SolidMasse moléculaire :407.21PF-6274484
CAS :PF-6274484 is an EGFR inhibitor with Ki values of 0.14 and 0.18 nM for EGFR-L858R/T790M and WT-EGFR, respectively.Formule :C18H14ClFN4O2Degré de pureté :97.71%Couleur et forme :SolidMasse moléculaire :372.78Ref: TM-T22396
2mg38,00€5mg57,00€1mL*10mM (DMSO)63,00€10mg96,00€25mg177,00€50mg333,00€100mg495,00€500mg1.071,00€WS3
CAS :WS3, a β cell proliferation inducer, regulates Erb3 binding protein-1 (EBP1) and the IκB kinase pathway.Formule :C28H30F3N7O3Degré de pureté :97.93% - 99.94%Couleur et forme :SolidMasse moléculaire :569.58CL-387785
CAS :CL-387785 is an irreversible EGFR inhibitor with IC50 of 370 pM; overcomes T790M mutation resistance.Formule :C18H13BrN4ODegré de pureté :99.56% - 99.62%Couleur et forme :SolidMasse moléculaire :381.23Epitinib
CAS :Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).Formule :C24H26N6O2Couleur et forme :SolidMasse moléculaire :430.5Tyrphostin B44, (+) enantiomer
CAS :Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-)Formule :C18H16N2O3Degré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :308.33Ref: TM-T22450
1mg39,00€5mg82,00€1mL*10mM (DMSO)90,00€10mg115,00€25mg192,00€50mg264,00€100mg380,00€200mg515,00€AG-1478
CAS :AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
Formule :C16H14ClN3O2Degré de pureté :99.03% - 99.71%Couleur et forme :SolidMasse moléculaire :315.75Mubritinib
CAS :Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.Formule :C25H23F3N4O2Degré de pureté :98.61% - 99.85%Couleur et forme :SolidMasse moléculaire :468.47Tuxobertinib
CAS :Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations. BDTX-189 exhibits anticancer activity.Formule :C29H29ClN6O4Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :561.03Ref: TM-T9072
2mg38,00€5mg57,00€1mL*10mM (DMSO)71,00€10mg90,00€25mg178,00€50mg334,00€100mg497,00€200mg712,00€SU5214
CAS :SU5214 is a modulator of tyrosine kinase signal transduction.Formule :C16H13NO2Degré de pureté :99.45% - 99.55%Couleur et forme :SolidMasse moléculaire :251.28WHI-P258
CAS :WHI-P258, a weak JAK3 inhibitor, is used as a negative control in drug development.Formule :C16H15N3O2Degré de pureté :99.66% - 99.92%Couleur et forme :SolidMasse moléculaire :281.31G5-7
CAS :G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39Ref: TM-T8742
1mg35,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€AG-494
CAS :AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Formule :C16H12N2O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :280.28Endoxifen (Z-isomer)
CAS :Endoxifen Z-isomer (EDX) is a key active metabolite of tamoxifen with higher affinity and specificity to estrogen receptors that inhibits aromatase activity.Formule :C25H27NO2Degré de pureté :99.19% - 99.81%Couleur et forme :SolidMasse moléculaire :373.49Ref: TM-T2280
1mg34,00€5mg66,00€1mL*10mM (DMSO)75,00€10mg88,00€25mg167,00€50mg259,00€100mg389,00€200mg563,00€AG 555
CAS :AG 555 (Tyrphostin B46) is an EGFR tyrosine kinase inhibitor.Formule :C19H18N2O3Degré de pureté :98.02% - 99.94%Couleur et forme :SolidMasse moléculaire :322.36Cetuximab
CAS :Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM).Formule :C107H179N35O36S7Degré de pureté :95 - 98.60%Couleur et forme :LiquidMasse moléculaire :145.54 kDalavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26Ref: TM-T4185
1mg42,00€2mg55,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€Canertinib
CAS :Canertinib (CI-1033), a pan-erbB inhibitor, effectively targets esophageal cancer in vitro/vivo, altering metabolism and reducing growth and hypoxia.Formule :C24H25ClFN5O3Degré de pureté :98% - >99.99%Couleur et forme :White Or Similar To White Crystalline PowderMasse moléculaire :485.94EAI045
CAS :EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.Formule :C19H14FN3O3SDegré de pureté :98.00% - 99.12%Couleur et forme :SolidMasse moléculaire :383.4MTX-211
CAS :MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Formule :C20H14Cl2FN5O2SDegré de pureté :97.6% - >99.99%Couleur et forme :SolidMasse moléculaire :478.33Ref: TM-T4296
1mg60,00€2mg89,00€5mg167,00€1mL*10mM (DMSO)170,00€10mg260,00€25mg439,00€50mg605,00€100mg802,00€200mg1.099,00€Neratinib
CAS :Neratinib (HKI-272) (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor for HER2 and EGFR (IC50: 59/92 nM), respectively.Formule :C30H29ClN6O3Degré de pureté :96.17% - 99.85%Couleur et forme :SolidMasse moléculaire :557.04NS309
CAS :NS309 activates SK/KCa2, IK/KCa3.1 (0.12-1.2 μM EC50, 10-90 nM EC50), and Kv11.1 channels; doesn't affect BK/KCa1.1; modulates neuronal firing.Formule :C8H4Cl2N2O2Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :231.04Ref: TM-T4612
5mg54,00€1mL*10mM (DMSO)59,00€10mg65,00€25mg113,00€50mg205,00€100mg305,00€200mg445,00€500mg712,00€Zorifertinib
CAS :Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor.Formule :C22H23ClFN5O3Degré de pureté :98.20% - 99.36%Couleur et forme :White To Off-White SolidMasse moléculaire :459.9Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),
Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14
