Syk
Les inhibiteurs de la kinase splénique (Syk) sont des composés qui ciblent Syk, une kinase impliquée dans la signalisation des cellules immunitaires et la régulation de l'angiogenèse. Syk joue un rôle dans les réponses inflammatoires qui peuvent contribuer à l'angiogenèse tumorale. L'inhibition de Syk peut réduire la formation de vaisseaux sanguins induite par l'inflammation dans les tumeurs, ce qui rend ces inhibiteurs précieux en thérapie anticancéreuse et dans la recherche sur l'inflammation. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de Syk de haute qualité pour soutenir vos recherches en immunologie, oncologie et angiogenèse.
37 produits trouvés pour "Syk".
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Piceatannol
CAS :Formule :C14H12O4Degré de pureté :>98.0%(HPLC)Couleur et forme :White to Light yellow to Light red powder to crystalMasse moléculaire :244.251,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS :Formule :C9H7NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :193.15621,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS :Formule :C14H12O4Degré de pureté :97%Couleur et forme :SolidMasse moléculaire :244.2427Adrenalone hydrochloride
CAS :Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Formule :C9H11NO3·HClDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :217.65Piceatannol
CAS :Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Formule :C14H12O4Degré de pureté :98.66% - 99.73%Couleur et forme :Light Tan To Yellow PowderMasse moléculaire :244.24Gusacitinib
CAS :Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).Formule :C24H28N8O2Degré de pureté :98.06% - 99.94%Couleur et forme :SolidMasse moléculaire :460.53Ref: TM-T14331
1mg39,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg116,00€25mg178,00€50mg333,00€100mg495,00€200mg710,00€Lanraplenib
CAS :Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Formule :C23H25N9ODegré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :443.5Ref: TM-T11824LL
1mg49,00€2mg71,00€5mg94,00€1mL*10mM (DMSO)109,00€10mg159,00€25mg275,00€50mg408,00€100mg600,00€Syk-IN-4
CAS :Syk-IN-4 is a potent, oral Syk inhibitor; blocks immune signaling; used for rheumatoid arthritis research.Formule :C21H25N9OCouleur et forme :SolidMasse moléculaire :419.48Ref: TM-T37077
1mg141,00€5mg335,00€1mL*10mM (DMSO)358,00€10mg597,00€25mg1.189,00€50mg1.935,00€100mg2.907,00€Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCouleur et forme :Odour SolidRef: TM-L2200
1mgÀ demander10μL*10mM (DMSO)À demander20μL*10mM (DMSO)À demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderSyk Kinase Peptide Substrate, Biotin labeled
The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.Formule :C76H108N18O24S1Couleur et forme :SolidMasse moléculaire :1689.9Cevidoplenib dimesylate
CAS :Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Formule :C27H35N7O9S2Degré de pureté :98%Couleur et forme :Yellow SolidMasse moléculaire :665.74Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Formule :C26H31N9O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :533.58Lanraplenib succinate
CAS :Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.Formule :C58H68N18O14Couleur et forme :SolidMasse moléculaire :1241.294MNS
CAS :Formule :C9H7NO4Degré de pureté :>98.0%(GC)Couleur et forme :Light yellow to Yellow to Green powder to crystalMasse moléculaire :193.16BAY 61-3606
CAS :BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFormule :C20H18N6O3Degré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :390.4BAY 61-3606 dihydrochloride
CAS :BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formule :C20H18N6O3·2HClDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :463.32Ref: TM-T6776
1mg35,00€5mg79,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€Flavanomarein
CAS :Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formule :C21H22O11Degré de pureté :98.63% - 99.54%Couleur et forme :SolidMasse moléculaire :450.39TAK-659 hydrochloride
CAS :TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Formule :C17H22ClFN6ODegré de pureté :99.28% - 99.82%Couleur et forme :SolidMasse moléculaire :380.85MNS
CAS :MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formule :C9H7NO4Degré de pureté :98.53%Couleur et forme :Yellow SolidMasse moléculaire :193.16R112
CAS :R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.Formule :C16H13FN4O2Degré de pureté :99.27% - 99.84%Couleur et forme :Yellow SolidMasse moléculaire :312.3Ref: TM-T3185
1mg37,00€2mg49,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg117,00€25mg207,00€50mg311,00€100mg462,00€500mg973,00€Fostamatinib Disodium
CAS :Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Formule :C23H24FN6O9P·2NaDegré de pureté :96.13% - 99.09%Couleur et forme :White SolidMasse moléculaire :624.42Ref: TM-T2605
1mg44,00€2mg52,00€5mg84,00€1mL*10mM (DMSO)110,00€10mg117,00€25mg210,00€50mg354,00€100mg530,00€500mg1.153,00€Fostamatinib
CAS :Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Formule :C23H26FN6O9PDegré de pureté :93.08% - 99.58%Couleur et forme :SolidMasse moléculaire :580.46Ref: TM-T6115
1mg40,00€2mg54,00€5mg84,00€1mL*10mM (DMSO)96,00€10mg112,00€25mg198,00€50mg318,00€100mg520,00€500mg1.134,00€Entospletinib
CAS :Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!Formule :C23H21N7ODegré de pureté :98.54% - 99.74%Couleur et forme :SolidMasse moléculaire :411.46Ref: TM-T6101
1mg35,00€2mg50,00€5mg77,00€1mL*10mM (DMSO)84,00€10mg92,00€25mg166,00€50mg245,00€100mg394,00€200mg585,00€R406
CAS :R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.Formule :C22H23FN6O5·C6H6O3SDegré de pureté :97.67% - 98.88%Couleur et forme :White SolidMasse moléculaire :628.63Ref: TM-T6174
1mg46,00€2mg57,00€5mg89,00€1mL*10mM (DMSO)120,00€10mg142,00€25mg299,00€50mg445,00€100mg647,00€R406 free base
CAS :R406 free base (R406 (free base)) is a potent Syk inhibitor.Formule :C22H23FN6O5Degré de pureté :97.64% - 99.11%Couleur et forme :SolidMasse moléculaire :470.45Ref: TM-T2467
1mg44,00€5mg66,00€1mL*10mM (DMSO)69,00€10mg92,00€25mg177,00€50mg319,00€100mg507,00€500mg1.063,00€PRT-060318
CAS :PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Formule :C18H24N6ODegré de pureté :99.98%Couleur et forme :White SolidMasse moléculaire :340.42PRT062607 hydrochloride
CAS :PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.Formule :C19H23N9O·HClDegré de pureté :97.7% - 99.81%Couleur et forme :SolidMasse moléculaire :429.91Ref: TM-T2696
1mg57,00€2mg81,00€5mg120,00€1mL*10mM (DMSO)132,00€10mg177,00€25mg309,00€50mg475,00€200mg898,00€Cerdulatinib
CAS :Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.54Ref: TM-T2487
1mg42,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)81,00€10mg101,00€25mg175,00€50mg268,00€100mg409,00€200mg573,00€500mg888,00€Cerdulatinib hydrochloride
CAS :Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Formule :C20H28ClN7O3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :482Syk Inhibitor II
CAS :Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Formule :C14H15F3N6ODegré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :340.3Sovleplenib
CAS :Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.Formule :C24H30N6O3SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :482.6Ref: TM-T32088
1mg120,00€5mg289,00€1mL*10mM (DMSO)308,00€10mg434,00€25mg737,00€50mg1.153,00€100mg1.791,00€200mg2.412,00€Syk-IN-3
CAS :Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.Formule :C24H28N4O3SDegré de pureté :97.29% - 99.64%Couleur et forme :SolidMasse moléculaire :452.57ER-27319
CAS :ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosineFormule :C20H22N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.4RO9021
CAS :RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Formule :C18H25N7ODegré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :355.44OXSI-2
CAS :OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formule :C18H15N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.39Lanraplenib monosuccinate
CAS :Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.Formule :C27H31N9O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :561.59MK-8457
CAS :MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].Formule :C24H25F3N4O3SCouleur et forme :SolidMasse moléculaire :506.54
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