Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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Cabozantinib hydrochloride
CAS :<p>Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6</p>Formule :C28H25ClFN3O5Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :537.96Iproniazid
CAS :<p>Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.</p>Formule :C9H13N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.22INH1
CAS :<p>INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.</p>Formule :C18H16N2OSDegré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :308.4Liensinine
CAS :<p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>Formule :C37H42N2O6Degré de pureté :98.92% - 99.93%Couleur et forme :White-Like PowderMasse moléculaire :610.74NUN82647
CAS :<p>NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.</p>Formule :C15H13N3O2SDegré de pureté :98.91%Couleur et forme :SolidMasse moléculaire :299.35Z-VAD(OMe)-FMK
CAS :<p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>Formule :C22H30FN3O7Degré de pureté :95.92% - 99.71%Couleur et forme :SolidMasse moléculaire :467.49Goserelin acetate
CAS :<p>Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.</p>Formule :C61H88N18O16Degré de pureté :99.77% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :1329.46Pevonedistat
CAS :<p>Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).</p>Formule :C21H25N5O4SDegré de pureté :95% - 99.92%Couleur et forme :SolidMasse moléculaire :443.52LQZ-7I
CAS :<p>LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors</p>Formule :C20H14F2N4Degré de pureté :99.81% - 99.87%Couleur et forme :SolidMasse moléculaire :348.35BAI1
CAS :<p>BAI1 (Bax channel blocker) is a potent inhibitor of Bax-mediated mitochondrial cytochrome C release (IC50: 0.52 μM).</p>Formule :C19H21Br2N3ODegré de pureté :97.74%Couleur et forme :SolidMasse moléculaire :467.2Pictilisib
CAS :<p>Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).</p>Formule :C23H27N7O3S2Degré de pureté :98.69% - 99.97%Couleur et forme :SolidMasse moléculaire :513.64ON1231320
CAS :<p>ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.</p>Formule :C22H15F2N5O3SDegré de pureté :97.31%Couleur et forme :SolidMasse moléculaire :467.45Mimosine
CAS :<p>L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.</p>Formule :C8H10N2O4Degré de pureté :99.2% - 99.84%Couleur et forme :Crystals From Water SolidMasse moléculaire :198.18Etomoxir sodium salt
CAS :<p>Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis.</p>Formule :C15H18ClO4·NaDegré de pureté :99.34% - 99.82%Couleur et forme :SolidMasse moléculaire :320.74ICCB-19 hydrochloride
CAS :<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Formule :C12H22ClN3OSDegré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :291.84Isosorbide Mononitrate
CAS :<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Formule :C6H9NO6Degré de pureté :98.16%Couleur et forme :Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionMasse moléculaire :191.14TPCK
CAS :<p>TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis</p>Formule :C17H18ClNO3SDegré de pureté :97.33%Couleur et forme :PowderMasse moléculaire :351.85LY-294002 hydrochloride
CAS :<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Formule :C19H17NO3·HClDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :343.81Rotenone
CAS :<p>Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.</p>Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42AP-III-a4
CAS :<p>AP-III-a4 (ENOblock) (ENOblock) is the first nonsubstrate analogue inhibitor of enolase with IC50 of 0.576 μM.</p>Formule :C31H43FN8O3Degré de pureté :98.24% - 99.90%Couleur et forme :SolidMasse moléculaire :594.72Fluazinam
CAS :<p>Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.</p>Formule :C13H4Cl2F6N4O4Degré de pureté :98% - 99.7%Couleur et forme :Light Yellow CrystalsMasse moléculaire :465.09RO8994
CAS :<p>RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).</p>Formule :C31H31Cl2FN4O4Degré de pureté :99.31% - 99.44%Couleur et forme :SolidMasse moléculaire :613.51Cabozantinib
CAS :<p>Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).</p>Formule :C28H24FN3O5Degré de pureté :99.68% - 99.88%Couleur et forme :SolidMasse moléculaire :501.51AMG-337
CAS :<p>AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337 inhibits MET kinase activity (IC50: < 5 nM).</p>Formule :C23H22FN7O3Degré de pureté :99.26% - 99.9%Couleur et forme :SolidMasse moléculaire :463.46Larotrectinib sulfate
CAS :<p>Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).</p>Formule :C21H22F2N6O2·H2O4SDegré de pureté :98.62% - 99.76%Couleur et forme :SolidMasse moléculaire :526.51Avitinib maleate
CAS :<p>Avitinib maleate is a pyrrolopyrimidine-based irreversible epidermal growth factor receptor (EGFR) inhibitor.</p>Formule :C30H30FN7O6Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :603.61PCNA-I1
CAS :<p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>Formule :C17H14N2O2SDegré de pureté :97.64%Couleur et forme :SolidMasse moléculaire :310.37GDC-0623
CAS :<p>GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.</p>Formule :C16H14FIN4O3Degré de pureté :98.95% - 99.02%Couleur et forme :SolidMasse moléculaire :456.21Butein
CAS :<p>Butein is a cAMP-specific PDE inhibitor, protein tyrosine kinase inhibitor, and SIRT1 activator.Cost-effective and quality-assured.</p>Formule :C15H12O5Degré de pureté :98.76% - >99.99%Couleur et forme :SolidMasse moléculaire :272.25XI-006
CAS :<p>NSC-207895 (XI-006) suppresses MDMX with IC50 of 2.5 μM, leading to enhanced p53 stabilization/activation and DNA damage, and regulates MDM2, an E3 ligase.</p>Formule :C11H13N5O4Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :279.25Benzarone
CAS :<p>Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.</p>Formule :C17H14O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :266.29Eribulin mesylate
CAS :<p>Eribulin mesylate (E7389), a microtubule inhibitor, treats metastatic breast cancer by halting cell division.</p>Formule :C41H63NO14SDegré de pureté :97.02% - >99.99%Couleur et forme :SolidMasse moléculaire :826Devimistat
CAS :<p>Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase</p>Formule :C22H28O2S2Degré de pureté :98.06% - 99.24%Couleur et forme :SolidMasse moléculaire :388.59Salidroside
CAS :<p>Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.</p>Formule :C14H20O7Degré de pureté :97.81%Couleur et forme :Red-Brown Fine PowderMasse moléculaire :300.3Ruxolitinib
CAS :<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Formule :C17H18N6Degré de pureté :99.4% - >99.99%Couleur et forme :SolidMasse moléculaire :306.36Prexasertib Mesylate Hydrate
CAS :<p>Prexasertib Mesylate Hydrate is a potent CHK1 inhibitor (IC50<1nM), also inhibits CHK2, RSK1, induces DNA breaks, apoptosis, and has anti-tumor effects.</p>Formule :C19H25N7O6SCouleur et forme :SolidMasse moléculaire :479.51SJ-172550
CAS :<p>SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).</p>Formule :C22H21ClN2O5Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :428.87BMS-536924
CAS :<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Formule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96Ceftiofur
CAS :<p>Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.</p>Formule :C19H17N5O7S3Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :523.56Kahweol
CAS :<p>Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB</p>Formule :C20H26O3Degré de pureté :99.26% - 99.86%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :314.42Oleic acid
CAS :<p>Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.</p>Formule :C18H34O2Degré de pureté :97.14% - 99.91%Couleur et forme :Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Masse moléculaire :282.46CBL0137
CAS :<p>CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB (EC50: 0.47 μM).</p>Formule :C21H24N2O2Degré de pureté :99.57% - 99.68%Couleur et forme :SolidMasse moléculaire :336.433,4 Dichloroisocoumarin
CAS :<p>3,4 Dichloroisocoumarin is a granzyme, cathepsin G, and neutrolphil elastase inhibitor</p>Formule :C9H4Cl2O2Degré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :215.03Thalidomide-NH-CH2-COOH TFA
CAS :<p>2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}acetic acid (trifluoroacetic acid) is mainly used in compounds Synthesis.</p>Formule :C17H14F3N3O8Degré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :445.3036α-Hederin
CAS :<p>Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.</p>Formule :C41H66O12Degré de pureté :99.44% - 99.89%Couleur et forme :SolidMasse moléculaire :750.96RA-9
CAS :<p>RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.</p>Formule :C19H15N3O5Degré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :365.34Acenocoumarol
CAS :<p>Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.</p>Formule :C19H15NO6Degré de pureté :99.95%Couleur et forme :Crystals SolidMasse moléculaire :353.33Citric acid
CAS :<p>Citric acid (Citro) is a weak organic tricarboxylic acid found in citrus fruits, a food additive and a natural preservative. High-Quality, Low-Cost!</p>Formule :C6H8O7Degré de pureté :98.88%Couleur et forme :White Solid CrystallineMasse moléculaire :192.12Quisinostat
CAS :<p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47Lumichrome
CAS :<p>Lumichrome, a riboflavin metabolite, influences plant growth, ascidian metamorphosis, bacterial communication, and blocks riboflavin uptake.</p>Formule :C12H10N4O2Degré de pureté :99.69% - 99.93%Couleur et forme :SolidMasse moléculaire :242.23Nocodazole
CAS :<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32Perillyl alcohol
CAS :<p>Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.</p>Formule :C10H16ODegré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :152.234-Methylsalicylic acid
CAS :<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Formule :C8H8O3Degré de pureté :99.64%Couleur et forme :Solid Solid CrystallineMasse moléculaire :152.15SBE13 Hydrochloride
CAS :<p>SBE13 Hydrochloride (SBE 13 HCl) is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.</p>Formule :C24H28Cl2N2O4Degré de pureté :99.00% - ≥95%Couleur et forme :SolidMasse moléculaire :479.4GW 441756
CAS :<p>GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.</p>Formule :C17H13N3ODegré de pureté :97.73% - 99.8%Couleur et forme :SolidMasse moléculaire :275.3Trametinib
CAS :<p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.</p>Formule :C26H23FIN5O4Degré de pureté :98% - 99.96%Couleur et forme :SolidMasse moléculaire :615.39Buparlisib
CAS :<p>Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).</p>Formule :C18H21F3N6O2Degré de pureté :95.32% - 98.45%Couleur et forme :SolidMasse moléculaire :410.39Benidipine
CAS :<p>Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.</p>Formule :C28H31N3O6Couleur et forme :SolidMasse moléculaire :505.56Mito-LND
CAS :<p>Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.</p>Formule :C43H45BrCl2N3OPDegré de pureté :97.25% - 98.34%Couleur et forme :SolidMasse moléculaire :801.62Rosiglitazone
CAS :<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Formule :C18H19N3O3SDegré de pureté :98.61% - 99.87%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :357.43Amsilarotene
CAS :<p>Amsilarotene (TAC101) blocks RB phosphorylation, boosts 2 CDK inhibitors, halts cell cycle, and reduces thymidylate synthase and cyclin A levels.</p>Formule :C20H27NO3Si2Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :385.6Bruceine D
CAS :<p>1.</p>Formule :C20H26O9Degré de pureté :95% - 99.99%Couleur et forme :SolidMasse moléculaire :410.42Rigosertib sodium
CAS :<p>Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.</p>Formule :C21H24NNaO8SDegré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :473.47SBI-0206965
CAS :<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Formule :C21H21BrN4O5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :489.32PF-3758309
CAS :<p>PF-3758309 (PF-03758309) (IC50=1.3 nM), a pyrrolopyrazole inhibitor of PAK4, has effective ATP-competition.</p>Formule :C25H30N8OSDegré de pureté :97.70%Couleur et forme :SolidMasse moléculaire :490.62Cyclopiazonic acid
CAS :<p>Cyclopiazonic acid (CPA) is a neurotoxic secondary metabolite (SM) made by A.</p>Formule :C20H20N2O3Degré de pureté :99.27% - 99.80%Couleur et forme :SolidMasse moléculaire :336.38Afimetoran
CAS :<p>Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.</p>Formule :C26H32N6ODegré de pureté :99.81% - 99.94%Couleur et forme :SolidMasse moléculaire :444.57AZD1208
CAS :<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formule :C21H21N3O2SDegré de pureté :97.24% - 99.83%Couleur et forme :SolidMasse moléculaire :379.48Omaveloxolone
CAS :<p>Omaveloxolone (RTA-408) (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.</p>Formule :C33H44F2N2O3Degré de pureté :98.7% - 99.92%Couleur et forme :SolidMasse moléculaire :554.71Propylparaben
CAS :<p>Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agent</p>Formule :C10H12O3Degré de pureté :99.84%Couleur et forme :White Solid CrystallineMasse moléculaire :180.20Tivantinib
CAS :<p>Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.</p>Formule :C23H19N3O2Degré de pureté :98% - 99.41%Couleur et forme :SolidMasse moléculaire :369.42AZD1208 hydrochloride
CAS :<p>AZD1208 hydrochloride is a highly selective, potent and orally active PIM inhibitor.</p>Formule :C21H22ClN3O2SCouleur et forme :SolidMasse moléculaire :415.94Selonsertib
CAS :<p>Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.</p>Formule :C24H24FN7ODegré de pureté :95.04% - 99.53%Couleur et forme :SolidMasse moléculaire :445.49Everolimus
CAS :<p>Everolimus (SDZ-RAD) is a potent mTOR inhibitor that binds to FKBP-12. It is used alone or in combination with calcineurin inhibitors.</p>Formule :C53H83NO14Degré de pureté :97.76% - 99.78%Couleur et forme :Off-White To Light Yellow PowdMasse moléculaire :958.22LYN-1604 hydrochloride
CAS :<p>LYN-1604 HCl activates ULK1 (EC50: 18.94 nM); key for studying TNBC.</p>Formule :C33H44Cl3N3O2Couleur et forme :SolidMasse moléculaire :621.08Pemetrexed disodium hemipenta hydrate
CAS :<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Formule :C20H21N5O6·2NaH2ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :518.43Necrostatin-1
CAS :<p>Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.</p>Formule :C13H13N3OSDegré de pureté :99.25% - >99.99%Couleur et forme :SolidMasse moléculaire :259.33Tiplaxtinin
CAS :<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formule :C24H16F3NO4Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :439.38BIX01294 (hydrochloride hydrate)
CAS :<p>BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.</p>Formule :C28H43Cl3N6O3Couleur et forme :SolidMasse moléculaire :618.04Tandutinib hydrochloride
CAS :<p>Tandutinib hydrochloride: FLT3 inhibitor (IC50 0.22 μM), targets c-Kit, PDGFR, treats AML, crosses blood-brain barrier.</p>Formule :C31H43ClN6O4Couleur et forme :SolidMasse moléculaire :599.16Etonogestrel
CAS :<p>Etonogestrel (Implanon) is a steroidal progestin used as hormonal contraceptives.</p>Formule :C22H28O2Degré de pureté :99.59% - 99.59%Couleur et forme :SolidMasse moléculaire :324.46SNS-032
CAS :<p>SNS-032 (BMS-387032) is a selective inhibitor of CDK2 and is 10- and 20-fold selective over CDK1/CDK4. SNS-032 is sensitive to CDK7/9, and no effect on CDK6.</p>Formule :C17H24N4O2S2Degré de pureté :98.27% - 99.91%Couleur et forme :SolidMasse moléculaire :380.53Pilaralisib analogue
CAS :<p>Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.</p>Formule :C21H16N6O2S2Degré de pureté :99.3% - 99.72%Couleur et forme :SolidMasse moléculaire :448.52Tripterin
CAS :<p>Tripterin (Celastrol) is an proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome with antioxidant and anti-inflammatory effects.</p>Formule :C29H38O4Degré de pureté :98.56% - 99.8%Couleur et forme :Red Crystalline PowderMasse moléculaire :450.61CA-5f
CAS :<p>CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.</p>Formule :C24H24N2O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.46AZD-8055
CAS :<p>AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.</p>Formule :C25H31N5O4Degré de pureté :98% - 99.69%Couleur et forme :SolidMasse moléculaire :465.54YK-4-279
CAS :<p>YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.</p>Formule :C17H13Cl2NO4Degré de pureté :99.80% - ≥95%Couleur et forme :SolidMasse moléculaire :366.2Enzastaurin
CAS :<p>Enzastaurin (LY317615) (LY317615) is an effective PKCβ selective inhibitor (IC50: 6 nM), 6- to 20-fold selectivity against PKCα/γ/ε.</p>Formule :C32H29N5O2Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :515.6MPP dihydrochloride (289726-02-9 Free base)
CAS :<p>MPP dihydrochloride is a highly selective antagonist of estrogen receptor alpha (ERα).</p>Formule :C29H33Cl2N3O3Couleur et forme :SolidMasse moléculaire :542.5PF-573228
CAS :<p>PF-573228 is an ATP-competitive FAK inhibitor. In a cell-free assay, the IC50 of FAK is 4 nM.</p>Formule :C22H20F3N5O3SDegré de pureté :96.58% - 99.51%Couleur et forme :SolidMasse moléculaire :491.49PD-1/PD-L1-IN-10
CAS :<p>PD-1/PD-L1-IN-10 is an orally available PD-1/PD-L1 inhibitor (IC50 value of 2.7 nM) that shows anti-tumor activity.Cost-effective and quality-assured.</p>Formule :C33H31N3O7Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :581.62AX-024
CAS :<p>AX-024 is an oral inhibitor of TCR-Nck with a 1 nM IC50, targeting SH3 domains, has low toxicity, is potent and selective, and reduces key cytokines.</p>Formule :C21H22FNO2Couleur et forme :SolidMasse moléculaire :339.4Linifanib
CAS :<p>Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and</p>Formule :C21H18FN5ODegré de pureté :98% - 98.24%Couleur et forme :SolidMasse moléculaire :375.4trans-Chalcone
CAS :<p>trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as</p>Formule :C15H12ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :208.26Fosbretabulin Disodium
CAS :<p>Fosbretabulin Disodium (CA 4P), a water-soluble prodrug of Combretastatin A4 (CA4), is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).</p>Formule :C18H19O8P·2NaDegré de pureté :97.43% - 99.96%Couleur et forme :White SolidMasse moléculaire :440.29Furanodienone
CAS :<p>1.</p>Formule :C15H18O2Degré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :230.3T0901317
CAS :<p>T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively; it inhibits nuclear factor/κB (NF/κB).</p>Formule :C17H12F9NO3SDegré de pureté :98% - 99.64%Couleur et forme :SolidMasse moléculaire :481.33(Z)-Mirin
CAS :<p>(Z)-Mirin is a potent Mre11–Rad50–Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.</p>Formule :C10H8N2O2SDegré de pureté :99.67% - 99.76%Couleur et forme :SolidMasse moléculaire :220.25FR 180204
CAS :<p>FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.</p>Formule :C18H13N7Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :327.34Se-Methylselenocysteine
CAS :<p>Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.</p>Formule :C4H9NO2SeDegré de pureté :99.49% - 99.87%Couleur et forme :White To Slightly Yellow PowderMasse moléculaire :182.08
