Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Semapimod tetrahydrochloride
CAS :<p>Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor.</p>Formule :C34H56Cl4N18O2Degré de pureté :97.21% - 99.8%Couleur et forme :SolidMasse moléculaire :890.74Pioglitazone
CAS :<p>Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!</p>Formule :C19H20N2O3SDegré de pureté :95% - 99.57%Couleur et forme :White PowderMasse moléculaire :356.44Probucol
CAS :<p>Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.</p>Formule :C31H48O2S2Degré de pureté :99.89% - 99.95%Couleur et forme :SolidMasse moléculaire :516.84α-Lipoic Acid
CAS :<p>α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in dietary supplements.</p>Formule :C8H14O2S2Degré de pureté :98.39% - 99.73%Couleur et forme :Forms Yellowish Flakes Light Yellow To Yellow PowderMasse moléculaire :206.33Tioxolone
CAS :<p>Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.</p>Formule :C7H4O3SDegré de pureté :97.79%Couleur et forme :Light Yellow To Beige PowderMasse moléculaire :168.17Azathioprine
CAS :<p>Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.</p>Formule :C9H7N7O2SDegré de pureté :99.89% - >99.99%Couleur et forme :Pale Yellow Crystals From 50% Aq Acetone For The Treatment Of Rheumatoid Arthritis A Known CarcinogenMasse moléculaire :277.26NVP-2
CAS :<p>NVP-2 selectively inhibits CDK9 (IC50: 0.514 nM), prompts apoptosis, and affects other CDKs (IC50: 0.584-0.706 μM).</p>Formule :C27H37ClN6O2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :513.07K-7174
CAS :<p>K-7174 is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-α.</p>Formule :C33H48N2O6Degré de pureté :97.12%Couleur et forme :SolidMasse moléculaire :568.749H-Xanthene-4-aceticacid, 5,6-dimethyl-9-oxo-
CAS :Formule :C17H14O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :282.2907Ref: IN-DA0035WP
1g192,00€5gÀ demander25gÀ demander50gÀ demander5mg37,00€25mg54,00€100mg68,00€250mg108,00€Tamsulosin hydrochloride
CAS :<p>Tamsulosin hydrochloride (Flomax hydrochloride) is the hydrochloride salt of tamsulosin, a sulfonamide derivative with α1 adrenergic antagonist activity.</p>Formule :C20H29ClN2O5SDegré de pureté :95.45% - 99.95%Couleur et forme :White To Off-White SolidMasse moléculaire :444.97TTNPB
CAS :<p>TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),</p>Formule :C24H28O2Degré de pureté :99.55%Couleur et forme :White SolidMasse moléculaire :348.48LYG-202
CAS :<p>LYG-202 is a novel flavonoid with piperazine substitution and antitumor effects in vivo and in vitro.LYG-202 induced apoptosis in MCF-7, MDA-MB-231, and MDA-MB-</p>Formule :C25H30N2O5Degré de pureté :98.05%Couleur et forme :SolidMasse moléculaire :438.52UCB-9260
CAS :<p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>Formule :C26H25N5ODegré de pureté :98.39% - 99.24%Couleur et forme :SolidMasse moléculaire :423.51HLY78
CAS :<p>HLY78, a Wnt/β-catenin activator, enhances Axin-LRP6 binding by targeting Axin's DIX domain.</p>Formule :C17H17NO2Degré de pureté :99.548%Couleur et forme :SolidMasse moléculaire :267.32Oxaprozin
CAS :<p>Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.</p>Formule :C18H15NO3Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :293.32Staurosporine
CAS :Formule :C28H26N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :466.5310Ref: IN-DA00365L
1g285,00€5gÀ demander10gÀ demander1mg44,00€25gÀ demander50gÀ demander25mg68,00€50mg102,00€100mg120,00€250mg157,00€500mg184,00€1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride (1:1), (3S)-
CAS :Formule :C22H24ClNO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.8815Roxadustat
CAS :<p>Roxadustat (FG-4592) is an orally bioavailable, hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), with potential anti-anemic activity.</p>Formule :C19H16N2O5Degré de pureté :99% - 99.88%Couleur et forme :SolidMasse moléculaire :352.34Oxidopamine hydrobromide
CAS :<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formule :C8H12BrNO3Degré de pureté :98.22% - 99.88%Couleur et forme :Beige To Brown Fine Crystalline PowderMasse moléculaire :250.09Levetiracetam
CAS :<p>Levetiracetam (SIB-S1) is a relatively unique anticonvulsant that is typically used in combination with other antiepileptic medications for partial onset</p>Formule :C8H14N2O2Degré de pureté :99.67% - 99.86%Couleur et forme :White Crystalline PowderMasse moléculaire :170.21Oenothein B
CAS :<p>Oenothein B inhibits PAR-glycohydrolase with antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor effects.</p>Formule :C68H48O44Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :1569.08eIF4E-IN-5
<p>eIF4E-IN-5 (Compound 6n) is a cell-permeable eIF4E inhibitor that binds to capped mRNA, thereby inhibiting cap-dependent translation [1].</p>Formule :C30H39Cl2N6O8PCouleur et forme :SolidMasse moléculaire :713.55Pipermethystine
<p>Pipermethystine is a useful organic compound for research related to life sciences and the catalog number is T124340.</p>Formule :C16H17NO4Couleur et forme :SolidMasse moléculaire :287.315Mcl1-IN-12
CAS :<p>Mcl1-IN-12 has anti-tumor activity.It is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.29 and 3.1 μM, respectively.</p>Formule :C45H46N4O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :803β-Glucuronide-dPBD-PEG5-NH2
CAS :<p>β-Glucuronide-dPBD-PEG5-NH2 is a β-glucuronide-linked pyrrolobenzodiazepine dimer that functions as a proagent for the synthesis of the antibody-drug conjugate</p>Formule :C78H101N7O35Couleur et forme :SolidMasse moléculaire :1696.66BODIPY FL thalidomide
CAS :<p>BODIPY FL thalidomide is a fluorescent probe that binds human cereblon protein with high affinity, exhibiting a dissociation constant (Kd) of 3.6 nM [1].</p>Formule :C37H43BF2N6O7Couleur et forme :SolidMasse moléculaire :732.58BcI-2/BcI-xI ligand 1
CAS :<p>BcI-2/BcI-xI ligand 1, functioning as a BcI-2/BcI-xI ligand, is utilized in the synthesis of PROTAC BcI-2/BcI-xI Degrader-1 .</p>Formule :C53H64ClF3N6O8S3Couleur et forme :SolidMasse moléculaire :1101.75MY-943
<p>MY-943, a potent inhibitor of tubulin polymerization and LSD1, exhibits anticancer properties by inducing G2/M phase arrest, promoting apoptosis, and</p>Formule :C30H36N4O6S2Couleur et forme :SolidMasse moléculaire :612.76SSE1806
<p>SSE1806, a podophyllotoxin derivative (a natural antimitotic agent), functions as a microtubule/tubulin inhibitor, exhibiting potent anticancer and</p>Formule :C21H18N2O5Couleur et forme :SolidMasse moléculaire :378.38Glutathione arsenoxide hydrochloride
<p>Glutathione arsenoxide hydrochloride: anti-cancer, inhibits tumour metabolism, targets ANT, promotes apoptosis, marks cell proteins.</p>Formule :C18H26AsClN4O9SDegré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :584.86Anti-inflammatory agent 61
<p>Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cells</p>Couleur et forme :Odour SolidTanfanercept
CAS :<p>Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.</p>Couleur et forme :LiquidBIM-46174 HCl
<p>BIM-46174 HCl is a G-protein inhibitor with anticancer activity that induces cysteine 3-dependent apoptosis.</p>Formule :C22H31ClN4OSDegré de pureté :99.77% - 99.77%Couleur et forme :SolidMasse moléculaire :435.03rac-CCT-250863 HCl
<p>rac-CCT-250863 HCl: NEK 2 inhibitor, halts cell cycle, anti-cancer growth, boosts Pomalidomide-induced apoptosis.</p>Formule :C24H26ClF3N4O2SDegré de pureté :98.21%Couleur et forme :SoildMasse moléculaire :527VEGFR-2-IN-66
<p>VEGFR-2-IN-66 (Compound 6) is an orally active VEGFR-2 inhibitor with an IC50 of 0.509 µM and an IC50 value of 7.48 μM for inhibiting MCF-7 cell proliferation. Its anticancer activity is exerted through cell cycle arrest, induction of apoptosis (Apoptosis), and modulation of gene expression, making it suitable for breast cancer research.</p>Couleur et forme :Odour SolidNDI-Lyso
CAS :<p>NDI-Lyso is an anticancer agent targeting lysosomes, functioning through an enzyme-induced self-assembly (EISA) mechanism catalyzed by Cathepsin B. In cancer cell lysosomes, it forms rigid long fibers, promoting lysosomal swelling, lysosomal membrane permeabilization (LMP), and membrane disruption. This leads to non-classical caspase-independent apoptosis (Apoptosis). NDI-Lyso demonstrates significant selective anticancer activity across various cancer cell lines and drug-resistant cancer cells (IC50 approximately 10 μM), while exhibiting low toxicity to normal cells (IC50 > 60 μM).</p>Formule :C71H100N22O13Couleur et forme :SolidMasse moléculaire :1469.69PROTAC HIF-1α degrader-1
<p>PROTAC HIF-1α degrader-1 (compound V2) is an effective proteolysis-targeting chimeric (PROTAC) degrader of hypoxia-inducible factor-1α (HIF-1α), with an IC50 value of 7.54 µM. This compound exhibits anti-proliferative activity, reduces HIF-1α protein expression, and induces apoptosis.</p>Formule :C51H72N6O7SCouleur et forme :SolidMasse moléculaire :913.22DL-Sulforaphane N-acetyl-L-cysteine
CAS :<p>DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC), induces apoptosis through α-microtubulin and phosphorylation of ERK1/2-mediated Stathmin-1, and Hsp70 (NSCLC).</p>Formule :C11H20N2O4S3Couleur et forme :SolidMasse moléculaire :340.48Anticancer agent 39
CAS :<p>Compound B12, a JOA derivative, collapses MMP to induce apoptosis, inhibits cloning/migration, and has an IC50 of 0.39 μM against HGC-27 cells.</p>Formule :C50H65N5O10Couleur et forme :SolidMasse moléculaire :896.08BMH-7 HCl
<p>BMH-7 HCl is a p53 activator, showing anti-cancer activity by activating the p53 pathway.</p>Formule :C20H22ClN5ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :383.88Bcl-xL antagonist 2
CAS :<p>Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM.</p>Formule :C21H16N4O3S2Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :436.51MEK/PI3K-IN-1
CAS :<p>MEK/PI3K-IN-1 (6r) is a dual MEK/PI3K inhibitor; IC50: 124 nM (MEK1), 130 nM (PI3Kα), 236 nM (PI3Kδ). It reduces pAKT, pERK1/2, and hinders tumor growth.</p>Formule :C36H37F5IN9O6Couleur et forme :SolidMasse moléculaire :913.63Odoroside A
CAS :<p>Odoroside A, from Nerium oleander leaves, induces cancer cell death via ROS/p53, causing apoptosis and cell cycle arrest.</p>Formule :C30H46O7Couleur et forme :SolidMasse moléculaire :518.68β-Amyloid (1-40) (rat)
CAS :<p>Rat form of the beta-Amyloid (1-40) peptide</p>Formule :C190H291N51O57SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4233.76Bcl-2-IN-4
CAS :<p>Bcl-2-IN-4: potent, selective, oral Bcl-2 inhibitor with 1.5 nM IC50, >200x selectivity over Bcl-xL.</p>Formule :C46H50ClN9O7SCouleur et forme :SolidMasse moléculaire :908.46SM-164 Hydrochloride (957135-43-2 free base)
<p>SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.</p>Formule :C62H85ClN14O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1157.88TAS-117
CAS :<p>TAS-117, a PKB/Akt inhibitor, is used potentially for the treatment of solid tumors.</p>Formule :C26H24N4O2Couleur et forme :SolidMasse moléculaire :424.49TQB-2858
<p>TQB-2858 is a bifunctional fusion protein composed of an anti-PD-L1 monoclonal antibody fused with the extracellular domain of the TGF-β receptor. It exhibits high affinity for PD-L1, TGF-β1, and TGF-β3, and demonstrates a high target occupancy rate for PD-L1. TQB-2858 can be used in research on osteosarcoma and alveolar soft part sarcoma (ASPS).</p>Couleur et forme :Odour LiquidThalidomide-O-C4-COOH
CAS :<p>Thalidomide-O-C4-COOH is a synthetic E3 ligase linker derived from Thalidomide for PROTAC tech.</p>Formule :C18H18N2O7Couleur et forme :SolidMasse moléculaire :374.3447Mcl-1 inhibitor 15
<p>Mcl-1 Inhibitor 15 (Compound (Ra)-15), with a K i of 0.02 nM, is utilized in cancer research [1].</p>Formule :C40H42ClFN6O4SCouleur et forme :SolidMasse moléculaire :757.32G-Glu-Val
CAS :<p>G-Glu-Val (γ-glutamyl-L-valine, H-Glu-Val -OH), a flavour-regulating dipeptide, is a major contributor to "mellow".</p>Formule :C10H18N2O5Couleur et forme :SolidMasse moléculaire :246.26R1-ICR-5
CAS :<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formule :C54H70N8O7S2Couleur et forme :SolidMasse moléculaire :1007.31SACLAC
CAS :<p>SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity used in the study of acute myeloid leukemia and cancer.</p>Formule :C20H40ClNO3Degré de pureté :97.03%Couleur et forme :SoildMasse moléculaire :377.99Vonlerolizumab
CAS :<p>Vonlerolizumab (MOXR 0916) is a humanized IgG OX40 agonist monoclonal antibody with potential in cancer and immune disease research.</p>Degré de pureté :SDS-PAGE:97.3%;SEC-HPLC:99.4%Couleur et forme :LiquidMasse moléculaire :145.25 kDaVEGFR-2-IN-64
<p>VEGFR-2-IN-64 (Compound 28) is an inhibitor of VEGFR2 with an IC50 of 27.8 nM. It suppresses the proliferation of cancer cells A549, T-47D, and Caco-2, exhibits anti-migration and anti-colony formation activities in T-47D cells, and induces apoptosis in T-47D cells.</p>Formule :C72H123N9O6Couleur et forme :SolidMasse moléculaire :1210.8Inuviscolide
CAS :<p>Inuviscolide induces apoptosis, G2/M arrest in melanoma, and has anti-cancer, anti-inflammatory effects.</p>Formule :C15H20O3Couleur et forme :SolidMasse moléculaire :248.32RO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Couleur et forme :Odour LiquidAnagrelide hydrochloride monohydrate
CAS :<p>Anagrelide HCl monohydrate is a platelet-reducing imidazoquinazoline for ET and PV research.</p>Formule :C10H10Cl3N3O2Couleur et forme :SolidMasse moléculaire :310.56Flavopiridol
CAS :<p>Flavopiridol (Alvocidib) blocks CDK1/2/4/6 by competing with ATP (IC50 ~40 nM); 7.5x selectivity over CDK7; also inhibits EGFR, PKA. In Phase 1/2 trials.</p>Formule :C21H20ClNO5Degré de pureté :97.74% - 99.86%Couleur et forme :SolidMasse moléculaire :401.84Estradiol (cypionate)
CAS :<p>Estradiol cypionate (Depofemin), the 17 β-cyclopentylpropinate ester of estradiol, inhibits ET-1 synthesis via estrogen receptor.</p>Formule :C26H36O3Degré de pureté :99.53% - >99.99%Couleur et forme :White Or Off-White Crystalline PowderMasse moléculaire :396.56BWA-522
<p>BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL)</p>Formule :C43H51ClN4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.34GGTI298 Trifluoroacetate
CAS :<p>GGTI298 trifluoroacetate (GGTI298TFA salt) is a geranylgeranyltransferase I inhibitor that causes cell cycle arrest and induces apoptosis.</p>Formule :C27H33N3O3S·C2HF3O2Degré de pureté :98.07% - >99.99%Couleur et forme :SolidMasse moléculaire :593.66TNF-α-IN-6
CAS :<p>TNF-α-IN-6 is an orally efficacious allosteric inhibitor of TNFα ( K D = 6.8 nM).</p>Formule :C26H25N9O2Couleur et forme :SolidMasse moléculaire :495.5477,3′,5′-Trihydroxyflavanone
CAS :<p>7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, promotes apoptotic cell death in MCF-7 cells by augmenting Bax expression.</p>Formule :C15H12O5Couleur et forme :SolidMasse moléculaire :272.25DH-18
<p>DH-18 is an inhibitor of matrix metalloproteinase-2 (MMP-2), exhibiting IC50 values of 139.45 nM for MMP-2, 518.11 nM for MMP-9, and 833.34 nM for MMP-8. The compound promotes cell apoptosis and causes cell cycle arrest in the G0/G1 phase. DH-18 also inhibits cell growth, making it potential for research in chronic myeloid leukemia.</p>Formule :C26H23F6N3O5SCouleur et forme :SolidMasse moléculaire :603.53(Rac)-BIO8898
CAS :<p>(Rac)-BIO8898 is a chemical compound that serves as an inhibitor of the co-stimulatory interaction between CD40 and CD154.</p>Formule :C53H64N8O6Couleur et forme :SolidMasse moléculaire :909.13Tubulin polymerization-IN-72
<p>Tubulin polymerization-IN-72 (Compound 4a4) is a microtubule synthesis inhibitor with anticancer properties. By binding to the colchicine site, it disrupts the polymerization of tubulin, resulting in the arrest of cancer cells at the G2/M phase and inducing apoptosis (Apoptosis). The IC50 for its activity against cancer cells is 0.4-2.7 nM.</p>Formule :C19H19FN4OCouleur et forme :SolidMasse moléculaire :338.379RET-IN-4
CAS :<p>RET-IN-4: Oral RET inhibitor, IC50 ~1 nM for variants. Selective over JAK2/FLT3. Potent anticancer use.</p>Formule :C27H31FN10O2Couleur et forme :SolidMasse moléculaire :546.611YB-0158 ammonium
<p>YB-0158 ammonium (Wnt pathway inhibitor 2 ammonium) is a reverse-rotation peptidomimetic with translation-enhancing potential and anticancer activity.</p>Formule :C32H40N9O7PDegré de pureté :99.14% - 99.18%Couleur et forme :SolidMasse moléculaire :693.69AS-99 free base
CAS :<p>AS-99 is a first-in-class, potent and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 μM, Kd= 0.89 μM) with anti-leukemic activity.</p>Formule :C27H30F3N5O3S2Couleur et forme :SolidMasse moléculaire :593.68CQ-ER
<p>CQ-ER is a Coumarin-quinazolinone-based photosensitizer targeting the endoplasmic reticulum (ER). It induces ferroptosis, thereby enhancing photodynamic therapy (PDT).</p>Formule :C33H33N7O6SCouleur et forme :SolidMasse moléculaire :655.72Mcl-1 antagonist 1
CAS :<p>Mcl-1 antagonist 1 is a Mcl-1 protein antagonist.</p>Formule :C41H54ClF2N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :850.42DMUP
CAS :<p>DMUP inhibits CD47-SIRPα, induces apoptosis, boosts macrophage activity in A549 cells, and has antitumor properties.</p>Formule :C24H24Cl2N2O10PtCouleur et forme :SolidMasse moléculaire :766.45Dapirolizumab
<p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.5 kDaThalidomide-NH-PEG2-COOH
CAS :<p>Thalidomide-NH-PEG2-COOH: a synthesized E3 ligase ligand-linker with cereblon ligand and PROTAC linker.</p>Formule :C20H23N3O8Couleur et forme :SolidMasse moléculaire :433.4172-aminobenzo[d]thiazol-6-ol
CAS :<p>2-aminobenzo[d]thiazol-6-ol: antimicrobial, antioxidant, anticancer; may trigger cancer cell apoptosis.</p>Formule :C7H6N2OSDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :166.2FLT3-IN-29
<p>FLT3-IN-29 (Compound MY-10) is an FLT3 inhibitor with IC50 values of 6.5 nM and 10.3 nM for FLT3-ITD and FLT3-D835Y mutants, respectively. It induces cell cycle arrest at the G0/G1 phase and effectively triggers apoptosis (Apoptosis). Additionally, FLT3-IN-29 reduces reactive oxygen species (ROS) and mitochondrial membrane potential (MMP), displaying anti-leukemic properties.</p>Formule :C25H30N6O2Couleur et forme :SolidMasse moléculaire :446.545PROTAC Bcl2 degrader-1
CAS :<p>PROTAC Bcl2 degrader-1 is a PROTAC, which potently and selectively induces the degradation of Mcl-1 (IC50: 11.81 μM) and Bcl-2 (IC50: 4.94 μM; DC50: 3.0 μM).</p>Formule :C45H45BrN6O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :941.84CDK-TCIP1
CAS :<p>CDK-TCIP1 is a bivalent molecule that links the CDK9 inhibitor SNS-032 with the BCL6 ligand BI3812. It effectively and specifically kills cells overexpressing BCL6, with an EC50 of 7.7 nM for SUDHL5 cells.</p>Formule :C48H62ClN11O8S2Couleur et forme :SolidMasse moléculaire :1020.66Thalidomide-NH-PEG4-COOH
CAS :<p>Thalidomide-NH-PEG4-COOH is a E3 ligase ligand-linker for synthesizing the selective degrader dCBP-1 targeting p300/CBP.</p>Formule :C24H31N3O10Couleur et forme :SolidMasse moléculaire :521.523Anticancer agent 104
<p>Anticancer agent 104 has anticancer activity, and induces cancer cell apoptosis [1] .</p>Formule :C34H47F3N2O2S2Couleur et forme :SolidMasse moléculaire :636.87Kdo2-Lipid A ammonium
CAS :<p>Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.</p>Formule :C110H214N6O39P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2306.84COG-1410 acetate
<p>COG-1410 acetate is an apolipoprotein E-derived peptide and can be used in studies about neurological diseases.</p>Formule :C66H125N21O16Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :1468.83DAPK Substrate Peptide
CAS :<p>DAPK Substrate Peptide is a synthetic peptide substrate for death-associated protein kinase (DAPK) (Km = 9 μM).</p>Formule :C70H115N25O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1578.82HMGB1-IN-1
<p>HMGB1-IN-1 (compound 6) exhibits potent inhibition of NO production in RAW264.7 cells, with an IC50 of 15.9 ± 0.6 μM, and effectively disrupts the HMGB1/NF-κB/</p>Formule :C57H75N3O15Couleur et forme :SolidMasse moléculaire :1042.22VEGFR2/HDAC1-IN-1
<p>VEGFR2/HDAC1-IN-1 (compound 13) is a potent dual inhibitor of VEGFR-2 and HDAC, with IC50 values of 57.83 nM for VEGFR-2 and 9.82 nM for HDAC.</p>Degré de pureté :98%Couleur et forme :Odour Solidcis-Clovamide
CAS :<p>cis-Clovamide is a naturally occurring phenolic compound with noteworthy antioxidant, anti-inflammatory, and antiapoptotic properties.</p>Formule :C18H17NO7Couleur et forme :SolidMasse moléculaire :359.334Asunercept
CAS :<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Couleur et forme :Liquid(E)-C-HDMAPP (ammonium salt)
CAS :<p>Alkyl phosphates like (E)-C-HDMAPP activate γδ-T cells, resist hydrolysis, and boost TNF-α synthesis and γδ-T cell count in vivo.</p>Formule :C6H23N3O7P2Couleur et forme :SolidMasse moléculaire :311.21Tripchlorolide
<p>Tripchlorolide is a useful organic compound for research related to life sciences and the catalog number is T126047.</p>Formule :C20H25ClO6Couleur et forme :SolidMasse moléculaire :396.86Necroptosis-IN-4
<p>Necroptosis-IN-4 is an effective inhibitor of necroptosis, specifically targeting RIP kinase 1 (RIPK1) without inhibitory activity against RIPK3. It exhibits weak inhibitory effects on VEGFR1/2 and PDGFR-α.</p>Couleur et forme :Odour SolidBAY1082439
CAS :<p>BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2].</p>Formule :C25H30N6O5Degré de pureté :100%Couleur et forme :SolidMasse moléculaire :494.54HDAC-IN-57
CAS :<p>HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4</p>Formule :C21H19N3O4Degré de pureté :98.38%Couleur et forme :SoildMasse moléculaire :377.39Oxythiamine
CAS :<p>Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.</p>Formule :C12H16N3O2SDegré de pureté :96.14% - 99.51%Couleur et forme :SolidMasse moléculaire :266.34OICR12694 TFA
CAS :<p>OICR12694 (JNJ-65234637) TFA, an orally active B cell lymphoma 6 (BCL6) inhibitor [1], demonstrates effectiveness in targeting BCL6 pathways.</p>Formule :C29H28ClF3N8O4·xC2HF3O2Couleur et forme :SolidNSC90616
<p>NSC90616 is a mutant p53 rescue compound [1] .</p>Formule :C23H30FNa2O9PCouleur et forme :SolidMasse moléculaire :546.43SB-1295
<p>SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells.</p>Formule :C23H22ClNO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.88CDK8-IN-13
CAS :<p>CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity.</p>Formule :C14H11N3ODegré de pureté :99.28%Couleur et forme :SoildMasse moléculaire :237.26Antiproliferative agent-59
<p>Antiproliferative agent-59 (Compound 14u) acts as an inhibitor of tubulin polymerization. Demonstrating anticancer activity in Huh7, SGC-7901, and MCF-7 cell lines, this compound achieves IC50 values of 0.03, 0.18, and 0.13 μM, respectively. Additionally, it arrests the cell cycle at the G2/M phase and induces apoptosis in Huh7 cells. In a xenograft mouse model utilizing Huh7 cells, Antiproliferative agent-59 exhibits antitumor effects against hepatocellular carcinoma without significant toxicity.</p>Formule :C26H22N2O3Couleur et forme :SolidMasse moléculaire :410.463-Hydroxyterphenyllin
CAS :<p>3-Hydroxyterphenyllin from A. candidus is a fungal compound with antioxidant, anticancer, antibacterial, and antiviral effects.</p>Formule :C20H18O6Couleur et forme :SolidMasse moléculaire :354.35
![2-aminobenzo[d]thiazol-6-ol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT77346.webp&w=3840&q=75)
