Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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KF24345
CAS :<p>KF24345 is an inhibitor of adenosine uptake.</p>Formule :C31H38N6O5Couleur et forme :SolidMasse moléculaire :574.67VEGFR-2-IN-22
CAS :<p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>Formule :C26H24ClFN4O6Couleur et forme :SolidMasse moléculaire :542.94HS56
CAS :<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Formule :C13H8ClN5OSCouleur et forme :SolidMasse moléculaire :317.75CTX1
CAS :<p>CTX1 is a small molecule activator of p53.</p>Formule :C14H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.26CAM 833
CAS :<p>CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.</p>Formule :C26H26ClFN4O5Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :528.96ATB-337
CAS :<p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>Formule :C23H15Cl2NO2S3Couleur et forme :SolidMasse moléculaire :504.47c-Fms-IN-12
CAS :<p>c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.</p>Formule :C30H32N6O6Couleur et forme :SolidMasse moléculaire :572.61Topoisomerase I inhibitor 2
CAS :<p>ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.</p>Formule :C18H15NO3Couleur et forme :SolidMasse moléculaire :293.32RET-IN-16
CAS :<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Formule :C31H29F3N8O2Couleur et forme :SolidMasse moléculaire :602.61GKK1032B
CAS :<p>GKK1032B: antiproliferative, antibacterial, halts HeLa S3, MCF-7, Vero cells, B. subtilis, M. tuberculosis.</p>Formule :C32H39NO4Couleur et forme :SolidMasse moléculaire :501.66SEC
CAS :<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Formule :C22H23ClN2O5Couleur et forme :SolidMasse moléculaire :430.88FD223
CAS :<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Formule :C17H12ClN5O2SCouleur et forme :SolidMasse moléculaire :385.83PI3Kδ-IN-10
CAS :<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Formule :C19H16ClN9Couleur et forme :SolidMasse moléculaire :405.84CAY10773
CAS :<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Formule :C22H17Cl2N5OCouleur et forme :SolidMasse moléculaire :438.31NSC-741909
CAS :<p>NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.</p>Formule :C16H14ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :271.74PD-1/PD-L1-IN 6
CAS :<p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>Formule :C25H26N2O3Couleur et forme :SolidMasse moléculaire :402.49Prinomastat hydrochloride
CAS :<p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>Formule :C18H22ClN3O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.97PI3Kα-IN-6
CAS :<p>PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.</p>Formule :C16H15IN2OSCouleur et forme :SolidMasse moléculaire :410.27p53 Activator 3
CAS :<p>Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Formule :C30H37F3N4O4SCouleur et forme :SolidMasse moléculaire :606.7Oxythiamine chloride HCl
CAS :<p>Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.</p>Formule :C12H17Cl2N3O2SCouleur et forme :SolidMasse moléculaire :338.25Caspase-9 Inhibitor III
CAS :<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Formule :C24H35ClN6O9Couleur et forme :SolidMasse moléculaire :587.02Esuberaprost Sodium
CAS :<p>Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.</p>Formule :C23H27FN4O2Couleur et forme :SolidMasse moléculaire :410.48Vin-C01
CAS :<p>Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.</p>Formule :C20H24N2OCouleur et forme :SolidMasse moléculaire :308.42Antitumor agent-70
CAS :<p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>Formule :C21H18N4O2Couleur et forme :SolidMasse moléculaire :358.39Declopramide
CAS :<p>Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.</p>Formule :C13H20ClN3ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :269.77Casein Kinase inhibitor A51
CAS :<p>Casein Kinase inhibitor A51 is a CK1α inhibitor with anticancer activity used in the study of breast and prostate cancer.</p>Formule :C18H25ClN6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :360.88Epofolate
CAS :<p>Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.</p>Formule :C67H92N16O22S3Couleur et forme :SolidMasse moléculaire :1569.74BIBU-1361 dihydrochloride
CAS :<p>BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.</p>Formule :C22H29Cl3FN7Couleur et forme :SolidMasse moléculaire :516.87HLI 373
CAS :<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Formule :C18H23N5O2Couleur et forme :SolidMasse moléculaire :341.41ALC67
CAS :<p>ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.</p>Formule :C15H15NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :289.35Polyphyllin II
CAS :<p>Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.</p>Formule :C44H70O16Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :855.02Anisperimus
CAS :<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Formule :C18H39N7O3Degré de pureté :98.10%Couleur et forme :SolidMasse moléculaire :401.55FAK-IN-5
CAS :<p>FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.</p>Formule :C29H29ClF3N3O4Couleur et forme :SolidMasse moléculaire :576.01Misetionamide
CAS :<p>Misetionamide: Oral oxathiazin-like, GAPDH inhibitor with anticancer properties for research use.</p>Formule :C3H7NO3SCouleur et forme :SolidMasse moléculaire :137.16L 741742 (free base)
CAS :<p>L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).</p>Formule :C23H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.91NSC 107512
CAS :<p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>Formule :C12H16N6O5Couleur et forme :SolidMasse moléculaire :324.29Quinidine Monosulfate
CAS :<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Formule :C40H50N4O8SCouleur et forme :SolidMasse moléculaire :746.92HDAC-IN-36
CAS :<p>HDAC-IN-36: Oral HDAC6 inhibitor, IC50 = 11.68 nM, promotes apoptosis & autophagy, anti-tumor & anti-metastatic, for breast cancer research.</p>Formule :C29H39N5O5Couleur et forme :SolidMasse moléculaire :537.65BMH-9
CAS :<p>BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formule :C19H27N3O2Couleur et forme :SolidMasse moléculaire :329.44GLUT4-IN-2
CAS :<p>GLUT4-IN-2, selective GLUT4 blocker; IC50: 6.8μM (GLUT4), 11.4μM (GLUT1). Induces apoptosis, G0/G1 arrest, has antitumor effects.</p>Formule :C17H11N3O4S2Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :385.42WK-298
CAS :<p>WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.</p>Formule :C35H38Cl2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :629.62SDZ 224-015
CAS :<p>SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.</p>Formule :C30H35Cl2N3O9Degré de pureté :95.49% - 95.49%Couleur et forme :SolidMasse moléculaire :652.52SKLB70326
CAS :<p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>Formule :C15H13N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.35DPQZ
CAS :<p>DPQZ is an anti-tubulin compound acting by inducing cell apoptosis in human oral cancer cells through Ras/Raf inhibition and MAP kinases activation.</p>Formule :C20H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.37PS121912
CAS :<p>PS121912 is a potent and selective inhibitor of VDR-coactivator.</p>Formule :C24H21F3N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.43CDK1/Cyc B-IN-1
CAS :<p>CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.</p>Formule :C14H12ClN3O2S2Couleur et forme :SolidMasse moléculaire :353.85Nimustine
CAS :<p>Nimustine: treats brain tumors, used with other drugs or radiotherapy for neoplasms.</p>Formule :C9H13ClN6O2Couleur et forme :SolidMasse moléculaire :272.69S130
CAS :<p>S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.</p>Formule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47OT-82
CAS :<p>OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.</p>Formule :C26H21FN4ODegré de pureté :98.91% - 99.315%Couleur et forme :SolidMasse moléculaire :424.47CAY10503
CAS :<p>CAY10503: proapoptotic, anti-growth agent; arrests cell cycle at G0-G1; IC50 = 7-23 μM; induces HL60 differentiation in 72 hours.</p>Formule :C18H14O3Couleur et forme :SolidMasse moléculaire :278.3STAT5-IN-2
CAS :<p>STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).</p>Formule :C26H27N3ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :397.51HJC0416
CAS :<p>HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.</p>Formule :C18H17ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.86Erasin
<p>Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.</p>Formule :C20H19N3O3Couleur et forme :SolidMasse moléculaire :349.38ANO1-IN-3
CAS :<p>ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].</p>Formule :C20H17NO3Couleur et forme :SolidMasse moléculaire :319.35Anticancer agent 67
CAS :<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Formule :C26H24F2N6O2S2Couleur et forme :SolidMasse moléculaire :554.63SCAL-255
CAS :<p>SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.</p>Formule :C27H28F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.54Rohinitib
CAS :<p>Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.</p>Formule :C29H31NO8Couleur et forme :SolidMasse moléculaire :521.56JMX0293
<p>JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).</p>Formule :C25H30Cl2N4O7Couleur et forme :SolidMasse moléculaire :569.43n-Octyl caffeate
CAS :<p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37(5Z,2E)-CU-3
CAS :<p>(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM</p>Formule :C16H12N2O4S3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :392.47ADU-S100
CAS :<p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>Formule :C20H24N10O10P2S2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :690.54VII-31
CAS :<p>VII-31 is an activator of the NEDDylation pathway, capable of inducing apoptosis in MCF-7, PC-3, and MGC-803 cells.</p>Formule :C23H25NO5SCouleur et forme :SolidMasse moléculaire :427.51CAY10682
CAS :<p>(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>Formule :C30H25BrFN5OCouleur et forme :SolidMasse moléculaire :570.45Sparfosic acid trisodium
CAS :<p>Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumour</p>Formule :C6H9NNaO8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.1IV-23
CAS :<p>IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.</p>Formule :C18H18BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.24IDT
CAS :<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Formule :C8H5NS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.26BMS-200
CAS :<p>BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.</p>Formule :C27H27F2NO6Couleur et forme :SolidMasse moléculaire :499.5VRT-043198
CAS :<p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>Formule :C22H29ClN4O6Couleur et forme :SolidMasse moléculaire :480.94PARP1-IN-31
CAS :<p>PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).</p>Formule :C22H15ClFN3O2Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :407.83USP7-IN-4
CAS :<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Formule :C29H34N6O3Degré de pureté :98.27% - 99.09%Couleur et forme :SolidMasse moléculaire :514.62Tubulin inhibitor 23
CAS :<p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>Formule :C26H23NO6SCouleur et forme :SolidMasse moléculaire :477.53TNF-α-IN-18
CAS :<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formule :C16H7ClF2O4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :336.67PC-046
CAS :<p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39Undecylprodigiosin
CAS :<p>Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.</p>Formule :C25H35N3OCouleur et forme :SolidMasse moléculaire :393.56Ki23057
CAS :<p>Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.</p>Formule :C30H35N3O4Couleur et forme :SolidMasse moléculaire :501.62BMS-1166 hydrochloride
CAS :<p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>Formule :C36H34Cl2N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :677.57OXPHOS-IN-1
CAS :<p>OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).</p>Formule :C19H29N3O6S2Couleur et forme :SolidMasse moléculaire :459.58PD-1/PD-L1-IN-20
CAS :<p>PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.</p>Formule :C30H26BrClN2O3Couleur et forme :SolidMasse moléculaire :577.9TNF-α-IN-1
CAS :<p>TNF-α-IN-1 is a TNF-α inhibitor.</p>Formule :C16H14ClN3O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :363.753-ATA
CAS :<p>3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.</p>Formule :C13H10N2SCouleur et forme :SolidMasse moléculaire :226.3MSN-125
CAS :<p>MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.</p>Formule :C36H38BrN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :688.61ROC-325
CAS :<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Formule :C28H27ClN4OSDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :503.06CMLD012072
CAS :<p>CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.</p>Formule :C32H32N2O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :556.61AG6033
CAS :<p>AG6033, a novel CRBN modulator, degrades GSPT1/IKZF1 and inhibits various tumors.</p>Formule :C30H23N5O4Couleur et forme :SolidMasse moléculaire :517.53HDAC-IN-39
CAS :<p>HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.</p>Formule :C27H26N4O4SCouleur et forme :SolidMasse moléculaire :502.58Flupenthixol
CAS :<p>Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.</p>Formule :C23H25F3N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.52FL3
CAS :<p>FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.</p>Formule :C25H23BrO5Couleur et forme :SolidMasse moléculaire :483.35Benpyrine
CAS :<p>Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.</p>Formule :C16H16N6OCouleur et forme :SolidMasse moléculaire :308.34HDAC-IN-31
CAS :<p>HDAC-IN-31: Oral HDAC inhibitor; targets HDAC1, 2, 3; weak on HDAC8; potential in fighting lymphoma.</p>Formule :C25H24N4O2Couleur et forme :SolidMasse moléculaire :412.48RIPK1-IN-15
CAS :<p>RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].</p>Formule :C19H19N3O2Couleur et forme :SolidMasse moléculaire :321.37ABT-100
CAS :<p>ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.</p>Formule :C27H19F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.46Sparfosic Acid
CAS :<p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>Formule :C6H10NO8PDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :255.12EGFR-IN-52
CAS :<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formule :C19H18N4O3SCouleur et forme :SolidMasse moléculaire :382.44SPRC
CAS :<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formule :C6H9NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :159.21Prexasertib mesylate
CAS :<p>Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.</p>Formule :C19H23N7O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.49A 410099.1
CAS :<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1Verrucarin J
CAS :<p>Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).</p>Formule :C27H32O8Couleur et forme :SolidMasse moléculaire :484.54Autophagy-IN-2
CAS :<p>Autophagy-IN-2 (7h) blocks autophagic flux, triggers cancer cell death, aids in triple-negative breast cancer study.</p>Formule :C17H19N5OCouleur et forme :SolidMasse moléculaire :309.37ICG-001
CAS :<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Formule :C33H32N4O4Degré de pureté :99.55% - 99.62%Couleur et forme :SolidMasse moléculaire :548.63MMP-9-IN-3
CAS :<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Formule :C29H25N3O4Couleur et forme :SolidMasse moléculaire :479.53PAK4-IN-2
CAS :<p>PAK4-IN-2 inhibits PAK4 with IC50 2.7 nM, arrests MV4-11 cells at G0/G1, and induces apoptosis, promising for cancer research.</p>Formule :C18H21ClN6Couleur et forme :SolidMasse moléculaire :356.85MI-1061
CAS :<p>MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).</p>Formule :C30H26Cl2FN3O4Couleur et forme :SolidMasse moléculaire :582.45Bax activator-1
CAS :<p>Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].</p>Formule :C29H36N4O3Couleur et forme :SolidMasse moléculaire :488.62EGFR-IN-51
CAS :<p>EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.</p>Formule :C21H15N3O2SCouleur et forme :SolidMasse moléculaire :373.43Ozarelix
CAS :<p>Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.</p>Formule :C72H96ClN17O14Couleur et forme :SolidMasse moléculaire :1459.09SHP2-IN-8
CAS :<p>SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.</p>Formule :C17H21Cl2N5SCouleur et forme :SolidMasse moléculaire :398.35Jolkinolide B
CAS :<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Formule :C20H26O4Degré de pureté :99.39% - 99.7%Couleur et forme :SolidMasse moléculaire :330.42Norartocarpetin
CAS :<p>Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24PARP-1-IN-2
CAS :<p>PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against</p>Formule :C22H15Cl2N3O2Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :424.28CHMFL-ABL/KIT-155
CAS :<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Formule :C33H38F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :609.68ZMF-10
CAS :<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Formule :C19H17F6N7OCouleur et forme :SolidMasse moléculaire :473.38αβ-Tubulin-IN-1
CAS :<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Formule :C25H19N3O3Couleur et forme :SolidMasse moléculaire :409.44SB 706504
CAS :<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formule :C24H19F3N8ODegré de pureté :98.686%Couleur et forme :SolidMasse moléculaire :492.46CT1-3
CAS :<p>CT1-3 is a potent anti-cancer compound targeting JNK/Bcl-2 pathways, blocking EMT in HCCs, and is non-toxic to liver/kidneys in mice.</p>Formule :C25H29NO3S2Couleur et forme :SolidMasse moléculaire :455.63ARN5187 trihydrochloride
CAS :<p>ARN5187 trihydrochloride: a REV-ERBβ inhibitor that blocks transcription, autophagy, and induces apoptosis with lysosomal cytotoxicity.</p>Formule :C24H35Cl3FN3OCouleur et forme :SolidMasse moléculaire :506.912LWG-301
<p>LWG-301, a GLS1 allosteric inhibitor, IC50 7 nM, impedes glutamine metabolism and prompts apoptosis; shows antitumor effects.</p>Formule :C28H38N8O3SCouleur et forme :SolidMasse moléculaire :566.72PD180970
CAS :<p>PD180970 is an inhibitor of Bcr-Abl with IC50s of 5 nM, 0.8 nM and 50 nM for the autophosphorylation of p210Bcr-Abl, Src and Kit.</p>Formule :C21H15Cl2FN4ODegré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :429.27MX107
CAS :<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49Anticancer agent 47
CAS :<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Formule :C19H14N2O4SCouleur et forme :SolidMasse moléculaire :366.39Antiproliferative agent-7
CAS :<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Formule :C28H32N4OCouleur et forme :SolidMasse moléculaire :440.58Glucocorticoid receptor modulator 1
CAS :<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Formule :C24H23ClN2O4SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :470.97HDAC-IN-51
<p>HDAC-IN-51 is an HDAC inhibitor.</p>Formule :C27H24N4O2Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :436.51MSN-50
CAS :<p>MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.</p>Formule :C36H38BrN3O6Couleur et forme :SolidMasse moléculaire :688.61Mcl1-IN-3
CAS :<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formule :C27H22ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.93Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Formule :C26H23NOCouleur et forme :SolidMasse moléculaire :365.47Tubulin/MMP-IN-2
CAS :<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Formule :C40H48NO11PCouleur et forme :SolidMasse moléculaire :749.78AP1867
CAS :<p>AP1867 is a synthetic FKBP12F36V-directed ligand.</p>Formule :C38H47NO11Couleur et forme :SolidMasse moléculaire :693.78BS-181
CAS :<p>BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.</p>Formule :C22H32N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.53RLX
CAS :<p>RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer,antitussive and anti-asthmatic activity,colon cancer，toxicity toward A549 cells..</p>Formule :C13H14N2ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :214.26S-Gem
CAS :<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Formule :C13H15F2N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.4NMK-TD-100
CAS :<p>NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.</p>Formule :C19H17N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.42JS-K
CAS :<p>JS-K is a Nitric oxide donor. It has antiproliferative activity.</p>Formule :C13H16N6O8Couleur et forme :SolidMasse moléculaire :384.3BRD0476
CAS :<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Formule :C35H38N4O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :674.76Quinidine polygalacturonate
CAS :<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Formule :C26H34N2O9Couleur et forme :SolidMasse moléculaire :518.22643LY5
CAS :<p>LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.</p>Formule :C15H11N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.33BN201
CAS :<p>BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.</p>Formule :C25H38FN5O4Degré de pureté :99.42% - 99.42%Couleur et forme :SolidMasse moléculaire :491.6p-nitro-Pifithrin-α
CAS :<p>p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.</p>Formule :C15H16BrN3O3SCouleur et forme :SolidMasse moléculaire :398.27Obatoclax
CAS :<p>Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.</p>Formule :C20H19N3ODegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :317.38RETRA
CAS :<p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>Formule :C11H12BrNO3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.25NVS-CECR2-1
CAS :<p>NVS-CECR2-1 is a CECR2 inhibitor with anti-tumor activity that inhibits chromatin binding of the CECR2 BRD.</p>Formule :C27H37N5O2SDegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :495.68RGB-286147
CAS :<p>RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.</p>Formule :C23H22Cl2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.35Verticillin A
CAS :<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formule :C30H28N6O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :696.84Propiomazine
CAS :<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Formule :C20H24N2OSDegré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :340.48UCB-6876
CAS :<p>UCB-6876 inhibits TNF signaling, stabilizes trimer asymmetry, shows concentration response, and is selective for TNFR1.</p>Formule :C17H18N2OCouleur et forme :SolidMasse moléculaire :266.34IHMT-TRK-284
CAS :<p>IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.</p>Formule :C25H27N7OSCouleur et forme :SolidMasse moléculaire :473.59(R)-eIF4A3-IN-2
CAS :<p>(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.</p>Formule :C25H19Br2ClN4O2Couleur et forme :SolidMasse moléculaire :602.71ZT55
CAS :<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Formule :C17H16N2O3Couleur et forme :SolidMasse moléculaire :296.32GL-V9
CAS :<p>GL-V9 is an AMPK activator, protecting against colitis-associated colorectal cancer by limiting NLRP3 inflammasome through autophagy.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47NSC114792
CAS :<p>NSC114792 is a selective JAK3 inhibitor.</p>Formule :C26H32N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.62MI-63
CAS :<p>MI-63 is a potent, specific, non-peptide inhibitor of the MDM2-p53 interaction.</p>Formule :C29H35Cl2FN4O3Couleur et forme :SolidMasse moléculaire :577.52hGGPPS-IN-2
CAS :<p>hGGPPS-IN-2, a C2-ThP-BP analogue, inhibits hGGPPS, targets MM cells, induces apoptosis, and has anti-myeloma effects.</p>Formule :C20H18FN5O7P2SCouleur et forme :SolidMasse moléculaire :553.4CAY10789
CAS :<p>CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.</p>Formule :C17H15NO2Couleur et forme :SolidMasse moléculaire :265.31TPB15
CAS :<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Formule :C18H9Cl4N5OCouleur et forme :SolidMasse moléculaire :453.11TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Formule :C20H21N5OSCouleur et forme :SolidMasse moléculaire :379.48pan-HER-IN-2
CAS :<p>pan-HER-IN-2 (Compound C6) is an orally active, reversible, broad-spectrum HER inhibitor that acts on EGFR (IC50: 0.72 nM), HER4 (IC50: 2.0 nM), EGFRT790M (IC50</p>Formule :C19H15BrClN5OCouleur et forme :SolidMasse moléculaire :444.71PQ1 Succinate
CAS :<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Formule :C25H28F3N3O6Couleur et forme :SolidMasse moléculaire :523.5BRD4 Inhibitor-15
CAS :<p>BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.</p>Formule :C22H21N3O2Couleur et forme :SolidMasse moléculaire :359.42YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formule :C24H24N6OCouleur et forme :SolidMasse moléculaire :412.49KRAS G12D inhibitor 14
CAS :<p>KRAS G12D inhibitor 14 is a potent inhibitor of KRAS G12D that binds KRAS G12D protein (Kd: 33 nM).</p>Formule :C20H19F3N4OSDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :420.45PDGFR-IN-1
CAS :<p>PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.</p>Formule :C25H30N8ODegré de pureté :99.13% - 99.49%Couleur et forme :SolidMasse moléculaire :458.56Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Formule :C24H27NO5Couleur et forme :SolidMasse moléculaire :409.47HI5
CAS :<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Formule :C42H43N5O8Couleur et forme :SolidMasse moléculaire :745.82MI-389
CAS :<p>MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.</p>Formule :C35H35FN6O6Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :654.69RO2468
CAS :<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Formule :C30H30Cl2FN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :614.49Anticancer agent 63
CAS :<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Formule :C17H24F3NOSeCouleur et forme :SolidMasse moléculaire :394.33CDK/HDAC-IN-2
CAS :<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Formule :C25H20Cl2N6O3Couleur et forme :SolidMasse moléculaire :523.37Anticancer agent 55
CAS :<p>Potent anticancer agent inhibits cell growth, migration, induces apoptosis; promising for prostate, breast cancer studies.</p>Formule :C28H21Br2FN2O2Couleur et forme :SolidMasse moléculaire :596.294CRA-026440
CAS :<p>CRA-026440(PCI-34051) is a highly potent HDAC inhibitor with inhibitory effects on HDAC1, HDAC2, HDAC3, HDAC6, HDAC8 and HDAC10 with Ki values of 4,14,11,15,7</p>Formule :C23H24N4O4Degré de pureté :96.42%Couleur et forme :SolidMasse moléculaire :420.46Nevanimibe
CAS :<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Formule :C27H39N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.62Mcl1-IN-4
CAS :<p>Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).</p>Formule :C28H26N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.58PARP1-IN-10
CAS :<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Formule :C20H23N3O5Couleur et forme :SolidMasse moléculaire :385.41IM-93
CAS :<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Formule :C21H28N4O2Couleur et forme :SolidMasse moléculaire :368.47CDK6/PIM1-IN-1
CAS :<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Formule :C25H28FN9Couleur et forme :SolidMasse moléculaire :473.55TH-Z835
CAS :<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Formule :C30H38N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.66Anti-inflammatory agent 22
CAS :<p>Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.</p>Formule :C22H16O6Couleur et forme :SolidMasse moléculaire :376.36Zonisamide sodium
CAS :<p>Zonisamide sodium is a 1,2 benzisoxazole derivative. It is the first agent of this chemical class to be developed as an antiepileptic drug.</p>Formule :C8H8N2NaO3SDegré de pureté :98%Couleur et forme :Off-White SolidMasse moléculaire :235.22VO-OHPic
CAS :<p>VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.</p>Formule :C12H10N2O8VCouleur et forme :SolidMasse moléculaire :361.16Didesmethylrocaglamide
CAS :<p>Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,</p>Formule :C27H27NO7Couleur et forme :SolidMasse moléculaire :477.51PDPOB
CAS :<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formule :C15H20O5Couleur et forme :SolidMasse moléculaire :280.32Semapimod
CAS :<p>Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.</p>Formule :C34H52N18O2Couleur et forme :SolidMasse moléculaire :744.9GLS1 Inhibitor-4
CAS :<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72DC-CPin711
CAS :<p>DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.</p>Formule :C23H22N4O2Couleur et forme :SolidMasse moléculaire :386.45CCT128930
CAS :<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Formule :C18H20ClN5Degré de pureté :99.07% - 99.18%Couleur et forme :SolidMasse moléculaire :341.84PD-1/PD-L1-IN-25
CAS :<p>"PD-1/PD-L1-IN-25 blocks PD-1/PD-L1 (IC50: 16.17 nM), boosting T-cell anti-tumor immunity, useful for cancer research."</p>Formule :C26H24ClN3O5Couleur et forme :SolidMasse moléculaire :493.94ZC0101
CAS :<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Formule :C17H15N3O2Couleur et forme :SolidMasse moléculaire :293.32PI3K/AKT-IN-2
CAS :<p>PI3K/AKT-IN-2 inhibits PI3K/AKT, EMT, induces apoptosis, and blocks tubulin polymerization.</p>Formule :C32H27BrO10Couleur et forme :SolidMasse moléculaire :651.45VMY-1-103
CAS :<p>VMY-1-103: a strong CDK inhibitor better than purvalanol B; halts prostate/breast cancer cell growth, induces apoptosis, may treat medulloblastoma.</p>Formule :C34H42ClN9O4SCouleur et forme :SolidMasse moléculaire :708.27PDK4-IN-1
CAS :<p>PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).</p>Formule :C22H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.41Darinaparsin
CAS :<p>Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.</p>Formule :C12H22AsN3O6SCouleur et forme :SolidMasse moléculaire :411.31(Z)-4EGI-1
CAS :<p>(Z)-4EGI-1, a Z-isomer, inhibits eIF4E/eIF4G; binds eIF4E (IC50=43.5 μM, Kd=8.74 μM); anticancer properties.</p>Formule :C18H12Cl2N4O4SCouleur et forme :SolidMasse moléculaire :451.28GW837016X
CAS :<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Formule :C25H20ClFN4OSCouleur et forme :SolidMasse moléculaire :478.97Anticancer agent 83
CAS :<p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>Formule :C20H19N5OSCouleur et forme :SolidMasse moléculaire :377.46SK-7041
CAS :<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formule :C19H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.39PCAF-IN-2
CAS :<p>PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.</p>Formule :C10H7F3N6Couleur et forme :SolidMasse moléculaire :268.2LLL3
CAS :<p>LLL3 is a small molecule STAT3 inhibitor.</p>Formule :C16H10O4Couleur et forme :SolidMasse moléculaire :266.25W1131
CAS :<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Formule :C23H19N5O4Couleur et forme :SolidMasse moléculaire :429.43Anticancer agent 42
CAS :<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Formule :C19H16Cl2N2O3Couleur et forme :SolidMasse moléculaire :391.25TJ08
CAS :<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Formule :C22H16FN3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :405.38Bcl-2/Mcl-1-IN-1
CAS :<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Formule :C28H23NO3Couleur et forme :SolidMasse moléculaire :421.49GGTI-2154
CAS :<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Formule :C24H28N4O3Couleur et forme :SolidMasse moléculaire :420.5
