Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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Fomesafen
CAS :<p>Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).</p>Formule :C15H10ClF3N2O6SDegré de pureté :99.91% - 99.93%Couleur et forme :White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicideMasse moléculaire :438.76Tryptophanamide
CAS :<p>Tryptophanamide is a chymotrypsin inhibitor.</p>Formule :C11H13N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :203.24Dimethoate
CAS :<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Formule :C5H12NO3PS2Degré de pureté :99.74% - 99.91%Couleur et forme :White Crystalline SolidMasse moléculaire :229.26Mitochonic Acid 35
CAS :<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Formule :C19H19NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.36CHMFL-ABL/KIT-155
CAS :<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Formule :C33H38F3N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :609.68NSC10010 hydrochloride
CAS :<p>NSC10010 inhibits gammaherpesvirus B-lymphomas by activating NF-κB and c-Myc pathways.</p>Formule :C31H42Cl2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.60Antitumor agent-62
CAS :<p>Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.</p>Formule :C21H19N3O9SCouleur et forme :SolidMasse moléculaire :489.46Zonisamide sodium
CAS :<p>Zonisamide sodium is a 1,2 benzisoxazole derivative. It is the first agent of this chemical class to be developed as an antiepileptic drug.</p>Formule :C8H8N2NaO3SDegré de pureté :98%Couleur et forme :Off-White SolidMasse moléculaire :235.22Propiomazine
CAS :<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Formule :C20H24N2OSDegré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :340.48KS106
CAS :<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Formule :C18H15BrF3N3O2SDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :474.32'-Deoxyadenosine
CAS :<p>2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.</p>Formule :C10H13N5O3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :251.24AKCI
CAS :<p>AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.</p>Formule :C19H27N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.46hGGPPS-IN-2
CAS :<p>hGGPPS-IN-2, a C2-ThP-BP analogue, inhibits hGGPPS, targets MM cells, induces apoptosis, and has anti-myeloma effects.</p>Formule :C20H18FN5O7P2SCouleur et forme :SolidMasse moléculaire :553.4DPBQ
CAS :<p>DPBQ (ZINC1620467) is a p53 activator.</p>Formule :C24H14N2O2Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :362.38SB 706504
CAS :<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formule :C24H19F3N8ODegré de pureté :98.686%Couleur et forme :SolidMasse moléculaire :492.46BIM-46174
CAS :<p>BIM-46174 has anticancer activity, inhibits the growth of a large number of human cancer cell lines, and induces caspase-3-dependent cancer cell apoptosis.</p>Formule :C22H30N4OSCouleur et forme :SolidMasse moléculaire :398.57HDAC1/2 and CDK2-IN-1
CAS :<p>Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.</p>Formule :C26H22ClN7OCouleur et forme :SolidMasse moléculaire :483.953-ATA
CAS :<p>3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.</p>Formule :C13H10N2SCouleur et forme :SolidMasse moléculaire :226.3BMS-200
CAS :<p>BMS-200 is a potent PD-1/PD-L1 interaction inhibitor with IC50 of 80 nM.</p>Formule :C27H27F2NO6Couleur et forme :SolidMasse moléculaire :499.5Estramustine phosphate
CAS :<p>Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.</p>Formule :C23H32Cl2NO6PCouleur et forme :SolidMasse moléculaire :520.38CT-1
CAS :<p>CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.</p>Formule :C29H23F3N4ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :500.51Ceranib-2
CAS :<p>Ceranib-2, a ceramidase inhibitor (IC50: 28 μM, SKOV3), reduces sphingosine/S1P and promotes apoptosis, showing anticancer properties.</p>Formule :C25H19NO3Degré de pureté :98.49%Couleur et forme :SolidMasse moléculaire :381.42HS56
CAS :<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Formule :C13H8ClN5OSCouleur et forme :SolidMasse moléculaire :317.75SD-36
CAS :<p>SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.</p>Formule :C59H62F2N9O12PDegré de pureté :98% - >99.99%Couleur et forme :SoildMasse moléculaire :1158.15PDE4-IN-10
CAS :<p>PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.</p>Formule :C18H13NCouleur et forme :SolidMasse moléculaire :243.3Declopramide
CAS :<p>Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.</p>Formule :C13H20ClN3ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :269.77ADU-S100
CAS :<p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>Formule :C20H24N10O10P2S2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :690.54Jolkinolide B
CAS :<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Formule :C20H26O4Degré de pureté :99.39% - 99.7%Couleur et forme :SolidMasse moléculaire :330.42Anticancer agent 57
CAS :<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Formule :C20H21Cl2NO2Couleur et forme :SolidMasse moléculaire :378.29Filanesib
CAS :<p>Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.</p>Formule :C20H22F2N4O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :420.48SKF1
CAS :<p>SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.</p>Formule :C23H37ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.01Anticancer agent 164
CAS :<p>CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid</p>Formule :C21H23F3N8O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :540.58Ac-IETD-CHO
CAS :<p>Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.</p>Formule :C21H34N4O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.52Antitumor agent-115
CAS :<p>Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line.</p>Formule :C19H38ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.96TP-472
CAS :<p>TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).</p>Formule :C20H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.38GW7845
CAS :<p>GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.</p>Formule :C29H28N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.54Apoptosis inducer 10
CAS :<p>Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity.</p>Formule :C27H46N2O2Couleur et forme :SolidMasse moléculaire :430.67CSRM617
CAS :<p>CSRM617: selective ONECUT2 inhibitor, Kd 7.43 uM, binds OC2-HOX, induces apoptosis, tolerable in mouse prostate cancer model.</p>Formule :C10H13N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :255.23YH-306
CAS :<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Formule :C19H18N2O2Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :306.36HMBPP triammonium
CAS :<p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>Formule :C5H15NO8P2Couleur et forme :SolidMasse moléculaire :279.122VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Formule :C26H20Cl2F3N5O3S2Couleur et forme :SolidMasse moléculaire :642.5WJ35435
CAS :<p>WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.</p>Formule :C20H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.4HX 630
CAS :<p>RXR agonist</p>Formule :C28H27NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :441.58HBV-IN-23
CAS :<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Formule :C25H27N3O3SCouleur et forme :SolidMasse moléculaire :449.57Nec-3a
CAS :<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Formule :C21H18F4N2O4Couleur et forme :SolidMasse moléculaire :438.37Quinidine Monosulfate
CAS :<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Formule :C40H50N4O8SCouleur et forme :SolidMasse moléculaire :746.92Anticancer agent 67
CAS :<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Formule :C26H24F2N6O2S2Couleur et forme :SolidMasse moléculaire :554.63EGFR-IN-52
CAS :<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formule :C19H18N4O3SCouleur et forme :SolidMasse moléculaire :382.44SPRC
CAS :<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formule :C6H9NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :159.21RGB-286147
CAS :<p>RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.</p>Formule :C23H22Cl2N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.35(R)-eIF4A3-IN-2
CAS :<p>(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.</p>Formule :C25H19Br2ClN4O2Couleur et forme :SolidMasse moléculaire :602.71PSB 0474
CAS :<p>P2Y6 receptor agonist</p>Formule :C17H20N2O13P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.29CDK9-IN-18
CAS :<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Formule :C27H20N8OCouleur et forme :SolidMasse moléculaire :472.5SK-7041
CAS :<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formule :C19H21N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.39Verticillin A
CAS :<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formule :C30H28N6O6S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :696.84CB-64D
CAS :<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Formule :C22H23NO2Couleur et forme :SolidMasse moléculaire :333.42Antitumor agent-56
CAS :<p>Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.</p>Formule :C28H28N2O10SCouleur et forme :SolidMasse moléculaire :584.59PERK-IN-5
CAS :<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Formule :C25H26F2N4O3Couleur et forme :SolidMasse moléculaire :468.5Metallo-β-lactamase-IN-5
CAS :<p>Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).</p>Formule :C19H16N4O3Couleur et forme :SolidMasse moléculaire :348.36HDAC1/6-IN-1
CAS :<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Formule :C32H45N7O4Couleur et forme :SolidMasse moléculaire :591.74CZS-241
<p>CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.</p>Formule :C26H24ClF2N9OCouleur et forme :SolidMasse moléculaire :551.98PI3K-IN-33
CAS :<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Formule :C23H21BrN6O2Couleur et forme :SolidMasse moléculaire :493.36PI3Kδ-IN-11
CAS :<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Formule :C27H21N5OCouleur et forme :SolidMasse moléculaire :431.49CDK/HDAC-IN-2
CAS :<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Formule :C25H20Cl2N6O3Couleur et forme :SolidMasse moléculaire :523.37Mcl1-IN-3
CAS :<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formule :C27H22ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.93DMH2
CAS :<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Formule :C27H25N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.52ZT55
CAS :<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Formule :C17H16N2O3Couleur et forme :SolidMasse moléculaire :296.32Quinidine polygalacturonate
CAS :<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Formule :C26H34N2O9Couleur et forme :SolidMasse moléculaire :518.22643AV123
CAS :<p>AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.</p>Formule :C11H14N4O2Couleur et forme :SolidMasse moléculaire :234.25Bcl-2/Mcl-1-IN-2
CAS :<p>Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.</p>Formule :C26H24ClNO3Couleur et forme :SolidMasse moléculaire :433.93SAHA-OH
CAS :<p>SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.</p>Formule :C15H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :294.35Apoptotic agent-1
CAS :<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Formule :C12H6ClN5O2SCouleur et forme :SolidMasse moléculaire :319.73Aurora kinase-IN-1
<p>Aurora kinase-IN-1: potent aurora kinase inhibitor, alters G1 cycle proteins, induces G1/S arrest and apoptosis, potential chemotherapy lead.</p>Formule :C30H25Br2N3O5Couleur et forme :SolidMasse moléculaire :667.34K145
CAS :<p>K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.</p>Formule :C18H24N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.46Apoptotic agent-3
CAS :<p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>Formule :C31H21N5OSCouleur et forme :SolidMasse moléculaire :511.6CCT373566
CAS :<p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.</p>Formule :C26H29ClF2N6O3Couleur et forme :SolidMasse moléculaire :547AMPK activator 11
CAS :<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Formule :C25H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.45Tubulin polymerization-IN-22
CAS :<p>Tubulin polymerization-IN-22 inhibits tubulin (IC50=8.1μM), blocks G2/M phase, and triggers apoptosis.</p>Formule :C19H16O4Couleur et forme :SolidMasse moléculaire :308.33NF-κB-IN-5
CAS :<p>NF-κB-IN-5 (compound 4d) is an orally active NF-κB inhibitor.</p>Formule :C23H27N3O4Couleur et forme :SolidMasse moléculaire :409.48GLS1 Inhibitor-4
CAS :<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formule :C29H27F3N10O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.72PDPOB
CAS :<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formule :C15H20O5Couleur et forme :SolidMasse moléculaire :280.32HDAC-IN-51
<p>HDAC-IN-51 is an HDAC inhibitor.</p>Formule :C27H24N4O2Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :436.51MX107
CAS :<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49PC-046
CAS :<p>PC-046, a tubulin binder, targets DPC4/SMAD4-deficient tumors, inhibits growth in vitro, and is effective in SCID mice with high oral bioavailability (71%).</p>Formule :C22H18N2O3Couleur et forme :SolidMasse moléculaire :358.39Tubulin inhibitor 23
CAS :<p>Potent Tubulin inhibitor 23 (IC50: 4.8 μM) induces apoptosis and has dose-dependent antiangiogenic properties, promising for leukemia research.</p>Formule :C26H23NO6SCouleur et forme :SolidMasse moléculaire :477.53CAY10682
CAS :<p>(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>Formule :C30H25BrFN5OCouleur et forme :SolidMasse moléculaire :570.45n-Octyl caffeate
CAS :<p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37NSC 107512
CAS :<p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>Formule :C12H16N6O5Couleur et forme :SolidMasse moléculaire :324.29CAY10773
CAS :<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Formule :C22H17Cl2N5OCouleur et forme :SolidMasse moléculaire :438.31FD223
CAS :<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Formule :C17H12ClN5O2SCouleur et forme :SolidMasse moléculaire :385.83SEC
CAS :<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Formule :C22H23ClN2O5Couleur et forme :SolidMasse moléculaire :430.88RET-IN-16
CAS :<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Formule :C31H29F3N8O2Couleur et forme :SolidMasse moléculaire :602.61EGFR/BRAFV600E-IN-1
CAS :<p>EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).</p>Formule :C24H24ClN3O3Couleur et forme :SolidMasse moléculaire :437.92MDM2/XIAP-IN-3
CAS :<p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>Formule :C29H30N2O5SCouleur et forme :SolidMasse moléculaire :518.62DNA topoisomerase II inhibitor 1
CAS :<p>Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.</p>Formule :C28H24N4O3SCouleur et forme :SolidMasse moléculaire :496.58CS1
CAS :<p>CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.</p>Formule :C16H12O3Couleur et forme :SolidMasse moléculaire :252.26Sarmustine
CAS :<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Formule :C6H11ClN4O3Degré de pureté :98.29% - 99.71%Couleur et forme :SolidMasse moléculaire :222.63Perphenazine dihydrochloride
CAS :<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Formule :C21H28Cl3N3OSDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :476.89LCS3
CAS :<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Formule :C11H7ClN2O4Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :266.64Gallium maltolate
CAS :<p>Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.</p>Formule :C18H15GaO9Degré de pureté :99.61% - 99.67%Couleur et forme :SolidMasse moléculaire :445.03RIPK3-IN-1
CAS :<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formule :C29H25FN4O4Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :512.53Cot inhibitor-1
CAS :<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formule :C27H27Cl2FN8Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :553.46LQZ-7F
CAS :<p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>Formule :C14H7N9O3Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :349.26EM-12
CAS :<p>EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.</p>Formule :C13H12N2O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :244.25AZA1
CAS :<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Formule :C22H20N6Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :368.43C6 Ceramide
CAS :<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Formule :C24H47NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :397.63Ro 08-2750
CAS :<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Formule :C13H10N4O3Degré de pureté :98.795%Couleur et forme :SolidMasse moléculaire :270.24OR-1896
CAS :<p>OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.</p>Formule :C13H15N3O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :245.28NLRP3/AIM2-IN-3
CAS :<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Formule :C16H14N2O2Degré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :266.29N6-Cyclopentyladenosine
CAS :<p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>Formule :C15H21N5O4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :335.36SYM 2081
CAS :<p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>Formule :C6H11NO4Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :161.16UC-112
CAS :<p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>Formule :C22H24N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :348.44Ro 90-7501
CAS :<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Formule :C20H16N6Degré de pureté :97.21% - 99.72%Couleur et forme :SolidMasse moléculaire :340.38Apostatin-1
CAS :<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Formule :C19H27N3OSDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :345.5BCL6-IN-7
CAS :<p>BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.</p>Formule :C18H15ClN6ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :366.8Cipepofol
CAS :<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Formule :C14H20ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :204.31XX-650-23
CAS :<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Formule :C18H12N2O2Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :288.3SB 699551 dihydrochloride
CAS :<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Formule :C34H47Cl2N3ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :584.66CCT020312
CAS :<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Formule :C31H30Br2N4O2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :650.4Mepazine
CAS :<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Formule :C19H22N2SDegré de pureté :99.88% - 99.92%Couleur et forme :SolidMasse moléculaire :310.46SLMP53-1
CAS :<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Formule :C20H18N2O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :318.37Stemazole
CAS :<p>Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.</p>Formule :C9H9N5OS2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :267.33HTH-01-091
CAS :<p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>Formule :C26H28Cl2N4O2Degré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :499.43Tiomolibdate diammonium
CAS :<p>Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.</p>Formule :H8MoN2S4Degré de pureté :98%Couleur et forme :Brown To Black Iridescent Crystalline PowderMasse moléculaire :260.28TT01001
CAS :<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Formule :C15H19Cl2N3O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :376.3P505-15 Acetate
CAS :<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Formule :C21H27N9O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :453.5Tubulin inhibitor 11
CAS :<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Formule :C22H23N3O3SDegré de pureté :98.32%Couleur et forme :SoildMasse moléculaire :409.5GSK854
CAS :<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Formule :C18H19ClN6O4S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :482.96Epristeride
CAS :<p>Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.</p>Formule :C25H37NO3Degré de pureté :98.12% - >99.99%Couleur et forme :SolidMasse moléculaire :399.57T025
CAS :<p>T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.</p>Formule :C21H18N8Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :382.42Imipramine
CAS :<p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>Formule :C19H24N2Degré de pureté :99.4%Couleur et forme :White To Off-White /Hydrochloride/ SolidMasse moléculaire :280.41CMLD-2
CAS :<p>CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.</p>Formule :C31H31NO6Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :513.58p53-MDM2-IN-1
CAS :<p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>Formule :C23H20ClN3O3Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :421.88A 419259 trihydrochloride
CAS :<p>A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).</p>Formule :C29H37Cl3N6ODegré de pureté :99.75% - 99.96%Couleur et forme :SolidMasse moléculaire :592NM-3
CAS :<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formule :C13H12O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :264.23TL4-12
CAS :<p>TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.</p>Formule :C25H27F3N6O2Degré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :500.52AQ4
CAS :<p>AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.</p>Formule :C22H28N4O4Degré de pureté :96.28% - 97.15%Couleur et forme :SolidMasse moléculaire :412.48Necrostatin-5
CAS :<p>Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.</p>Formule :C19H17N3O2S2Degré de pureté :98.03%Couleur et forme :SolidMasse moléculaire :383.49NSC49652
CAS :<p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>Formule :C14H11NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :225.24Triparanol
CAS :<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Formule :C27H32ClNO2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :438CTA 056
CAS :<p>CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.</p>Formule :C35H34N6ODegré de pureté :97.22% - 97.76%Couleur et forme :SolidMasse moléculaire :554.68Brigimadlin
CAS :<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Formule :C31H25Cl2FN4O3Degré de pureté :98.17%Couleur et forme :SolidMasse moléculaire :591.46CUDC-427
CAS :<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Formule :C29H36N6O4SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :564.7Droloxifene
CAS :<p>Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.</p>Formule :C26H29NO2Degré de pureté :99.86% - 99.97%Couleur et forme :Solid PowderMasse moléculaire :387.51CDK9-IN-7
CAS :<p>CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.</p>Formule :C29H37N7O2SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :547.71HS38
CAS :<p>HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.</p>Formule :C14H12ClN5O2SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :349.8AOH1160
CAS :<p>AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).</p>Formule :C25H20N2O3Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :396.44BC 11 hydrobromide
CAS :<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formule :C8H12BBrN2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :290.97Dasatinib hydrochloride
CAS :<p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>Formule :C22H27Cl2N7O2SDegré de pureté :99.88% - 99.98%Couleur et forme :SolidMasse moléculaire :524.47RO-5963
CAS :<p>RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).</p>Formule :C24H21ClF2N4O5Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :518.9PARP/PI3K-IN-1
CAS :<p>PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.</p>Formule :C33H28F4N8O3Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :660.62TAI-1
CAS :<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Formule :C24H21N3O3SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :431.51STAT3-IN-13
CAS :<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formule :C21H20N6O3SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :436.49DX3-213B
CAS :<p>DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.</p>Formule :C20H28F2N2O5S2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :478.57Lanperisone HCl
CAS :<p>Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.</p>Formule :C15H19ClF3NODegré de pureté :98.67% - >99.99%Couleur et forme :SolidMasse moléculaire :321.77Sabizabulin
CAS :<p>Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.</p>Formule :C21H19N3O4Degré de pureté :98.10% - 99.79%Couleur et forme :SolidMasse moléculaire :377.39Ciglitazone
CAS :<p>Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.</p>Formule :C18H23NO3SDegré de pureté :98.23% - 99.59%Couleur et forme :White Cyrstalline SolidMasse moléculaire :333.45UCB-5307
CAS :<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :343.42DCG066
CAS :<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Formule :C30H31F6N3O2Degré de pureté :98.26% - 98.38%Couleur et forme :SolidMasse moléculaire :579.58Anticancer agent 110
CAS :<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Formule :C18H13FN6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.41G244
CAS :<p>1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.</p>Formule :C29H30F2N4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :504.57RS1-PDK1 inhibitor
CAS :<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Formule :C15H9ClN2O2S3Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :380.89Minodronic acid
CAS :<p>Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.</p>Formule :C9H12N2O7P2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :322.15MBM-55
CAS :<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Formule :C28H27FN6O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :498.55EB1
CAS :<p>EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.</p>Formule :C18H14N4Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :286.33GSK-3β inhibitor 3
CAS :<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Formule :C18H14FNO2SDegré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :327.37EGFR-IN-11
CAS :<p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>Formule :C29H35N9O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :573.71UK-101
CAS :<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Formule :C25H48N2O5SiDegré de pureté :99.08% - 99.25%Couleur et forme :SolidMasse moléculaire :484.74MMRi64
CAS :<p>MMRi64 inhibits Mdm2-MdmX, boosts p53, triggers apoptosis, and is used in cancer research.</p>Formule :C22H17Cl2N3ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :410.3A09-003
CAS :<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Formule :C23H26N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :374.48RET-IN-23
CAS :<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Formule :C28H28FN11Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :537.59CSN5i-3
CAS :<p>CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.</p>Formule :C28H29F2N5O2Degré de pureté :99.56% - >99.99%Couleur et forme :SolidMasse moléculaire :505.56FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formule :C22H27F3N4O2SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :468.54CCT018159
CAS :<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Formule :C20H20N2O4Degré de pureté :98.78% - 99.79%Couleur et forme :SolidMasse moléculaire :352.38SPD304 dihydrochloride
CAS :<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53UNC0321
CAS :<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Formule :C27H45N7O3Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :515.69VAS 3947
CAS :<p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>Formule :C14H10N6OSDegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :310.33HS-276
CAS :<p>HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.</p>Formule :C24H29N5O2Degré de pureté :97.852% - 98.81%Couleur et forme :SolidMasse moléculaire :419.52Antifolate C2
CAS :<p>Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.</p>Formule :C19H21N5O6SDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.46HBDDE
CAS :<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Formule :C16H18O8Degré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :338.31SCFSkp2-IN-2
CAS :<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Formule :C17H20N4O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :312.37Deferitazole
CAS :<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Formule :C18H25NO7SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :399.46Alethine
CAS :<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Formule :C10H22N4O2S2Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :294.44GSK2593074A
CAS :<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Formule :C27H23N5OSDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :465.57TC-DAPK 6
CAS :<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Formule :C17H12N2O2Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :276.29CBS9106
CAS :<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Formule :C18H21ClF3N3O3Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :419.83Vamotinib
CAS :<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Formule :C29H27F3N6ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :532.56Prinomastat
CAS :<p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>Formule :C18H21N3O5S2Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :423.51KR-33493
CAS :<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formule :C20H18BrN3O3SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :460.34W146
CAS :<p>W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.</p>Formule :C16H27N2O4PDegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :342.37HBED
CAS :<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formule :C20H24N2O6Degré de pureté :97.35% - 98.58%Couleur et forme :SolidMasse moléculaire :388.41DB1976
CAS :<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Formule :C20H16N8SeDegré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :447.35ZDLD20
CAS :<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Formule :C22H22N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :386.45Trk-IN-9
CAS :<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Formule :C23H24ClFN6ODegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :454.93TNIK-IN-3
CAS :<p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>Formule :C23H18FN3O2Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :387.41Erastin2
CAS :<p>Erastin2 is an iron death inducer that induces cell death by binding to the lipophilic free radical trapping antioxidant ferrostatin-1 or the iron chelator DFO.</p>Formule :C36H35ClN4O4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :623.14MJN68390
CAS :<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Formule :C24H28ClN3O3Degré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :441.95D609
CAS :<p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>Formule :C11H15KOS2Degré de pureté :97.67% - 99.56%Couleur et forme :Off-White PowderMasse moléculaire :266.46NecroX-7
CAS :<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formule :C24H29N3O3SDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :439.57K-8012
CAS :<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Formule :C23H23FN4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :374.45
