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TNF

TNF

Les inhibiteurs du facteur de nécrose tumorale (TNF) sont des composés qui bloquent l'activité du TNF, une cytokine impliquée dans l'inflammation et la régulation de l'apoptose. Le TNF peut induire l'apoptose dans certains types cellulaires tout en favorisant la survie et l'inflammation dans d'autres. L'inhibition du TNF est cruciale dans le traitement des maladies auto-immunes, des affections inflammatoires chroniques et de certains cancers. Les inhibiteurs de TNF aident à moduler la réponse immunitaire et à réduire les dommages tissulaires causés par une inflammation excessive. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de TNF de haute qualité pour soutenir vos recherches en immunologie, inflammation et apoptose.

92 produits trouvés pour "TNF"

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  • Ruplizumab

    CAS :
    <p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>
    Degré de pureté :98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)
    Couleur et forme :Liquid
  • Conatumumab

    CAS :
    <p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>
    Degré de pureté :> 95% - > 95%
    Couleur et forme :Liquid
    Masse moléculaire :145 kDa (average)
  • Enavatuzumab

    CAS :
    Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.
    Degré de pureté :>95%
    Couleur et forme :Liquid
  • Iscalimab

    CAS :
    Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.
    Degré de pureté :>95%
    Couleur et forme :Liquid
  • Ozoralizumab

    CAS :
    Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.
    Degré de pureté :SDS-PAGE:> 95%;SEC-HPLC:95.6%
    Couleur et forme :Liquid
    Masse moléculaire :38.44 kDa
  • Utomilumab

    CAS :
    Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.
    Formule :C17H24N8O3
    Degré de pureté :95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)
    Couleur et forme :Liquid
    Masse moléculaire :142.77 kDa
  • Certolizumab pegol

    CAS :
    <p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>
    Degré de pureté :95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)
    Couleur et forme :Liquid
  • Teneliximab

    CAS :
    <p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>
    Degré de pureté :95.00% - 99.19% (SEC-HPLC)
    Couleur et forme :Liquid
    Masse moléculaire :146.06 kDa
  • Dacetuzumab

    CAS :
    <p>Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.</p>
    Degré de pureté :95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)
    Couleur et forme :Liquid
  • (S,S)-TAPI-1 FA


    (S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.
    Formule :C27H39N5O7
    Degré de pureté :97.61% - 99.72%
    Couleur et forme :Solid
    Masse moléculaire :545.63
  • Lucatumumab

    CAS :
    <p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>
    Degré de pureté :95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)
    Couleur et forme :Liquid
  • UCB-9260

    CAS :
    <p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>
    Formule :C26H25N5O
    Degré de pureté :98.39% - 99.24%
    Couleur et forme :Solid
    Masse moléculaire :423.51
  • Tilogotamab

    CAS :
    Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).
    Degré de pureté :95%
    Couleur et forme :Liquid
  • Relfovetmab

    CAS :
    Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .
    Couleur et forme :Liquid
  • Onfekafusp alfa

    CAS :
    Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.
    Couleur et forme :Liquid
  • Tengonermin

    CAS :
    Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.
    Couleur et forme :Liquid
  • Pegsunercept

    CAS :
    Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].
    Couleur et forme :Liquid
  • Zigakibart

    CAS :
    Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)
    Degré de pureté :95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)
    Couleur et forme :Liquid
  • Nerelimomab

    CAS :
    Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].
    Couleur et forme :Liquid
  • Telitacicept

    CAS :
    Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand
    Couleur et forme :Liquid
  • BMS-986156


    BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.
  • TNF-α (46-65), human

    CAS :
    Human TNF alpha (46-65) peptide.
    Formule :C110H172N24O30
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :2310.69
  • Sym029


    Sym029 is a human IgG monoclonal antibody (mAb) that targets TNFRSF5/CD40. It is applicable for cancer research. The suggested isotype control is Human IgG1 kappa, Isotype Control.
  • DSTYSLSSTLTLSK TFA


    DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.
    Formule :C66H108F3N15O28
    Couleur et forme :Solid
    Masse moléculaire :1616.64
  • Dazodalibep

    CAS :
    Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody that specifically targets CD40LG/TNFSF5 and is fused to human serum albumin (ALB/HSA) [1].
    Couleur et forme :Liquid
  • Ragifilimab

    CAS :
    <p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>
    Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%
    Couleur et forme :Liquid
    Masse moléculaire :146.46 kDa
  • Varlilumab

    CAS :
    <p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>
    Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.65%
    Couleur et forme :Liquid
    Masse moléculaire :146 kDa
  • TNF-α-IN-9

    CAS :
    TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.
    Formule :C17H14O4
    Degré de pureté :99.21%
    Couleur et forme :Soild
    Masse moléculaire :282.29
  • Anti-Mouse TNF α Antibody (TN3-19.12)


    <p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>
    Degré de pureté :95% - >10mg/ml
    Couleur et forme :Odour Liquid
  • RO7567132


    RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.
    Couleur et forme :Odour Liquid
  • Pamlectabart


    Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.
    Degré de pureté :95%
    Couleur et forme :Odour Liquid
  • Atibuclimab

    CAS :
    <p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>
    Degré de pureté :> 95% - > 95%
    Couleur et forme :Liquid
    Masse moléculaire :145.28 kDa
  • Tulinercept

    CAS :
    Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].
    Couleur et forme :Liquid
  • BIIB023


    BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.
    Couleur et forme :Odour Liquid
  • Acetyl tetrapeptide-2

    CAS :
    Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.
    Formule :C26H39N5O9
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :565.62
  • TNF-α Antagonist

    CAS :
    <p>TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with</p>
    Formule :C58H71N11O15S2
    Couleur et forme :Solid
    Masse moléculaire :1226.39
  • Giloralimab

    CAS :
    Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.
    Degré de pureté :95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)
    Couleur et forme :Liquid
  • Sotigalimab

    CAS :
    Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.
    Degré de pureté :98.50% - 98.50%
    Couleur et forme :Liquid
  • EJMC-1

    CAS :
    <p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>
    Formule :C17H11ClN2O4S
    Degré de pureté :98.38%
    Couleur et forme :Solid
    Masse moléculaire :374.8
  • Asunercept

    CAS :
    <p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>
    Couleur et forme :Liquid
  • HS-243

    CAS :
    <p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>
    Formule :C17H16N4O3
    Degré de pureté :98.62%
    Couleur et forme :Solid
    Masse moléculaire :324.33
  • Dapirolizumab


    <p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>
    Degré de pureté :>95%
    Couleur et forme :Liquid
    Masse moléculaire :145.5 kDa
  • Tanfanercept

    CAS :
    Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.
    Couleur et forme :Liquid
  • Placulumab

    CAS :
    Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.
    Couleur et forme :Liquid
  • Ranevetmab

    CAS :
    Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.
    Couleur et forme :Liquid
  • Lenercept

    CAS :
    <p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>
    Couleur et forme :Liquid
  • TNF α Protein, Human, Recombinant (aa 77-233, His)


    TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.
    Degré de pureté :Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :16 KDa (reducing condition)
  • TNF α Protein, Human, Recombinant (His & Avi), Biotinylated


    TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (aa 57-233, His)


    TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :18 KDa (reducing condition)
  • TNF α Protein, Rabbit, Recombinant


    Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.
    Degré de pureté :98% - > 99.9%
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :18 KDa (reducing condition)
  • TNF α Protein, Ferret, Recombinant (His)


    TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :18.88 kDa (predicted) same as Tris-Bis PAGE result.
  • TNF α Protein, Human, Recombinant (His & Avi)


    TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.
  • TNF α Protein, Cynomolgus, Recombinant (His)


    TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.
  • LASSBio-1135

    CAS :
    LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.
    Formule :C18H14N4
    Degré de pureté :99.09%
    Couleur et forme :Solid
    Masse moléculaire :286.33
  • R-7050

    CAS :
    <p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>
    Formule :C16H8ClF3N4S
    Degré de pureté :98.64% - 99.8%
    Couleur et forme :Solid
    Masse moléculaire :380.77
  • (Rac)-Benpyrine

    CAS :
    (Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.
    Formule :C16H16N6O
    Degré de pureté :98.44%
    Couleur et forme :Solid
    Masse moléculaire :308.34
  • Hispidol

    CAS :
    <p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>
    Formule :C15H10O4
    Degré de pureté :97.86% - 98.45%
    Couleur et forme :Solid
    Masse moléculaire :254.24
  • STING-IN-2

    CAS :
    STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.
    Formule :C15H16N2O4
    Degré de pureté :98.61%
    Couleur et forme :Solid
    Masse moléculaire :288.3
  • Roquinimex

    CAS :
    Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and
    Formule :C18H16N2O3
    Degré de pureté :97.69%
    Couleur et forme :Solid
    Masse moléculaire :308.33
  • N-Formyl-Met-Leu-Phe

    CAS :
    N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
    Formule :C21H31N3O5S
    Degré de pureté :98.69% - 98.69%
    Couleur et forme :Solid
    Masse moléculaire :437.55
  • C25-140

    CAS :
    <p>C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.</p>
    Formule :C26H31N7O
    Degré de pureté :98.81%
    Couleur et forme :Solid
    Masse moléculaire :457.57
  • Resatorvid

    CAS :
    <p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>
    Formule :C15H17ClFNO4S
    Degré de pureté :99.31% - >99.99%
    Couleur et forme :Solid
    Masse moléculaire :361.82
  • UTL-5g

    CAS :
    <p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>
    Formule :C11H8Cl2N2O2
    Degré de pureté :99.83%
    Couleur et forme :Solid
    Masse moléculaire :271.1
  • Tulisokibart

    CAS :
    Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.
    Degré de pureté :98.38% (SEC-HPLC) - > 95%
    Couleur et forme :Liquid
  • Dalnicastobart

    CAS :
    Dalnicastobart (LVGN-7409) is a humanized monoclonal antibody targeting CD40/TNFRSF5 with agonist activity, immunostimulatory and antitumor.
    Degré de pureté :95% - 97.4% (SDS-PAGE); 97.8% (SEC-HPLC)
    Couleur et forme :Liquid
  • Afimkibart

    CAS :
    Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.
    Degré de pureté :95% - 99.2% (SDS-PAGE); 95.3% (SEC-HPLC)
    Couleur et forme :Soild
  • Ravagalimab

    CAS :
    Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.
    Degré de pureté :95% - 96.9% (SDS-PAGE); 99.5% (SEC-HPLC)
    Couleur et forme :Liquid
  • Cifurtilimab

    CAS :
    <p>Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.</p>
    Degré de pureté :95%
    Couleur et forme :Liquid
  • Frexalimab

    CAS :
    Frexalimab (SAR441344; INX-021), a monoclonal antibody that targets the CD40 ligand (CD40L), shows promise for research in multiple sclerosis [1].
    Degré de pureté :95% - 95%
    Couleur et forme :Liquid
  • Toralizumab

    CAS :
    Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.
    Couleur et forme :Liquid
    Masse moléculaire :148.43 (kD)
  • Bleselumab

    CAS :
    Bleselumab (ASKP 1240) is a humanised monoclonal antibody targeting CD40, inhibiting immune responses, organ transplant rejection.
    Degré de pureté :95%
    Couleur et forme :Liquid
  • Tabalumab

    CAS :
    Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.
    Degré de pureté :95%
    Couleur et forme :Liquid
  • Iratumumab

    CAS :
    Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.
    Couleur et forme :Liquid
  • Licaminlimab


    <p>Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.</p>
    Couleur et forme :Odour Liquid
  • Anti-Mouse TNFR2 Antibody (TR75-54.7)


    Anti-Mouse TNFR2 Antibody is an Armenian Hamster-derived IgG inhibitor specifically targeting mouse TNFR2.
    Couleur et forme :Odour Liquid
  • Tecaginlimab

    CAS :
    Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.
    Couleur et forme :Liquid
  • Afelimomab

    CAS :
    Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].
    Couleur et forme :Liquid
  • Selicrelumab

    CAS :
    Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.
    Degré de pureté :98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)
    Couleur et forme :Liquid
  • VU0285655-1

    CAS :
    <p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>
    Formule :C25H27N5O2
    Degré de pureté :99.73%
    Couleur et forme :Solid
    Masse moléculaire :429.51
  • TNF-α-IN-1

    CAS :
    TNF-α-IN-1 is a TNF-α inhibitor.
    Formule :C16H14ClN3O5
    Degré de pureté :98.82%
    Couleur et forme :Solid
    Masse moléculaire :363.75
  • Mitazalimab

    CAS :
    Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.
    Degré de pureté :95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)
    Couleur et forme :Liquid
  • UCB-5307

    CAS :
    UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.
    Formule :C22H21N3O
    Degré de pureté :98.76%
    Couleur et forme :Solid
    Masse moléculaire :343.42
  • SPD304 dihydrochloride

    CAS :
    <p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>
    Formule :C32H34Cl2F3N3O2
    Degré de pureté :99.25%
    Couleur et forme :Solid
    Masse moléculaire :620.53
  • PK68

    CAS :
    PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.
    Formule :C22H24N4O3S
    Degré de pureté :98.09% - 99.64%
    Couleur et forme :Solid
    Masse moléculaire :424.52
  • C 87

    CAS :
    C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.
    Formule :C24H15ClN6O3S
    Degré de pureté :≥98%
    Couleur et forme :Solid
    Masse moléculaire :502.93
  • Trovafloxacin mesylate

    CAS :
    Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).
    Formule :C21H19F3N4O6S
    Degré de pureté :99.18%
    Couleur et forme :Solid
    Masse moléculaire :512.46
  • BMS-561392

    CAS :
    BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.
    Formule :C27H32N4O4
    Degré de pureté :99.16%
    Couleur et forme :Solid
    Masse moléculaire :476.57
  • Boserolimab

    CAS :
    <p>Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.</p>
    Couleur et forme :Liquid
  • CDC801

    CAS :
    <p>CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.</p>
    Formule :C23H24N2O5
    Degré de pureté :99.61%
    Couleur et forme :Solid
    Masse moléculaire :408.45
  • TNF-α-IN-12

    CAS :
    <p>TNF-α-IN-12, a TNF-α inhibitor with an IC50 of 0.1 μM, can reduce TNF-α blood levels [1].</p>
    Formule :C21H22O6
    Couleur et forme :Solid
    Masse moléculaire :370.4
  • TNF-α-IN-14

    CAS :
    TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].
    Formule :C22H26O6
    Couleur et forme :Solid
    Masse moléculaire :386.44
  • TNF-α-IN-2

    CAS :
    TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.
    Formule :C25H21ClF2N6O
    Degré de pureté :99.92%
    Couleur et forme :Solid
    Masse moléculaire :494.92