TNF
Les inhibiteurs du facteur de nécrose tumorale (TNF) sont des composés qui bloquent l'activité du TNF, une cytokine impliquée dans l'inflammation et la régulation de l'apoptose. Le TNF peut induire l'apoptose dans certains types cellulaires tout en favorisant la survie et l'inflammation dans d'autres. L'inhibition du TNF est cruciale dans le traitement des maladies auto-immunes, des affections inflammatoires chroniques et de certains cancers. Les inhibiteurs de TNF aident à moduler la réponse immunitaire et à réduire les dommages tissulaires causés par une inflammation excessive. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de TNF de haute qualité pour soutenir vos recherches en immunologie, inflammation et apoptose.
92 produits trouvés pour "TNF"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Dacetuzumab
CAS :<p>Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.</p>Degré de pureté :95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidTeneliximab
CAS :<p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>Degré de pureté :95.00% - 99.19% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.06 kDaEnavatuzumab
CAS :<p>Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.</p>Degré de pureté :>95%Couleur et forme :LiquidUCB-9260
CAS :<p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>Formule :C26H25N5ODegré de pureté :98.39% - 99.24%Couleur et forme :SolidMasse moléculaire :423.51Lucatumumab
CAS :<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>Degré de pureté :95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Couleur et forme :LiquidCertolizumab pegol
CAS :<p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>Degré de pureté :95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidRuplizumab
CAS :<p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>Degré de pureté :98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidUtomilumab
CAS :<p>Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.</p>Formule :C17H24N8O3Degré de pureté :95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :142.77 kDa(S,S)-TAPI-1 FA
<p>(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.</p>Formule :C27H39N5O7Degré de pureté :97.61% - 99.72%Couleur et forme :SolidMasse moléculaire :545.63Ozoralizumab
CAS :<p>Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.</p>Degré de pureté :SDS-PAGE:> 95%;SEC-HPLC:95.6%Couleur et forme :LiquidMasse moléculaire :38.44 kDaConatumumab
CAS :<p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145 kDa (average)Iscalimab
CAS :<p>Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.</p>Degré de pureté :>95%Couleur et forme :LiquidVarlilumab
CAS :<p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.65%Couleur et forme :LiquidMasse moléculaire :146 kDaZigakibart
CAS :<p>Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)</p>Degré de pureté :95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Couleur et forme :LiquidRagifilimab
CAS :<p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :146.46 kDaCot inhibitor-1 hydrochloride
<p>Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.</p>Formule :C27H28Cl3FN8Degré de pureté :98.26%Couleur et forme :SoildMasse moléculaire :589.92TNF-α-IN-9
CAS :<p>TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.</p>Formule :C17H14O4Degré de pureté :98.28%Couleur et forme :SoildMasse moléculaire :282.29Anti-Mouse TNF α Antibody (TN3-19.12)
<p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>Degré de pureté :95% - ＞10mg/mlCouleur et forme :Odour LiquidRO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Couleur et forme :Odour LiquidPamlectabart
<p>Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.</p>Degré de pureté :95%Couleur et forme :Odour LiquidRelfovetmab
CAS :<p>Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .</p>Couleur et forme :LiquidOnfekafusp alfa
CAS :<p>Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.</p>Couleur et forme :LiquidTengonermin
CAS :<p>Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.</p>Couleur et forme :LiquidPegsunercept
CAS :<p>Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].</p>Couleur et forme :LiquidNerelimomab
CAS :<p>Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].</p>Couleur et forme :LiquidAsunercept
CAS :<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Couleur et forme :LiquidTanfanercept
CAS :<p>Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.</p>Couleur et forme :LiquidPlaculumab
CAS :<p>Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.</p>Couleur et forme :LiquidRanevetmab
CAS :<p>Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.</p>Couleur et forme :LiquidLenercept
CAS :<p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>Couleur et forme :LiquidAtibuclimab
CAS :<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.28 kDaBIIB023
<p>BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.</p>Couleur et forme :Odour LiquidTNF-α Antagonist
CAS :<p>TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with</p>Formule :C58H71N11O15S2Couleur et forme :SolidMasse moléculaire :1226.39Giloralimab
CAS :<p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>Degré de pureté :95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Couleur et forme :LiquidSotigalimab
CAS :<p>Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.</p>Degré de pureté :98.50% - 98.50%Couleur et forme :LiquidDapirolizumab
<p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.5 kDaHS-243
CAS :<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formule :C17H16N4O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :324.33EJMC-1
CAS :<p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>Formule :C17H11ClN2O4SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :374.8Tilogotamab
CAS :<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Degré de pureté :95%Couleur et forme :LiquidTNF α Protein, Rabbit, Recombinant
<p>Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.</p>Degré de pureté :98% - > 99.9%Couleur et forme :Lyophilized PowderMasse moléculaire :18 KDa (reducing condition)TNF α Protein, Ferret, Recombinant (His)
<p>TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Cynomolgus, Recombinant (His)
<p>TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi)
<p>TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 57-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :18 KDa (reducing condition)TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
<p>TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 77-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.</p>Degré de pureté :Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Couleur et forme :Lyophilized PowderMasse moléculaire :16 KDa (reducing condition)QNZ
CAS :<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Formule :C22H20N4ODegré de pureté :99.17% - 99.18%Couleur et forme :White SolidMasse moléculaire :356.42R-7050
CAS :<p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>Formule :C16H8ClF3N4SDegré de pureté :98.64% - 99.8%Couleur et forme :SolidMasse moléculaire :380.77Hispidol
CAS :<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Formule :C15H10O4Degré de pureté :97.86% - 98.45%Couleur et forme :SolidMasse moléculaire :254.24Resatorvid
CAS :<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formule :C15H17ClFNO4SDegré de pureté :99.31% - >99.99%Couleur et forme :SolidMasse moléculaire :361.82Nodinitib-1
CAS :<p>Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.</p>Formule :C14H13N3O2SDegré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :287.34C25-140
CAS :<p>C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.</p>Formule :C26H31N7ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :457.57(Rac)-Benpyrine
CAS :<p>(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.</p>Formule :C16H16N6ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :308.34Roquinimex
CAS :<p>Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis and</p>Formule :C18H16N2O3Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :308.33LASSBio-1135
CAS :<p>LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.</p>Formule :C18H14N4Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :286.33UTL-5g
CAS :<p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>Formule :C11H8Cl2N2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :271.1STING-IN-2
CAS :<p>STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.</p>Formule :C15H16N2O4Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :288.3Tulisokibart
CAS :<p>Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.</p>Degré de pureté :98.38% (SEC-HPLC) - > 95%Couleur et forme :LiquidLicaminlimab
<p>Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.</p>Couleur et forme :Odour LiquidToralizumab
CAS :<p>Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.</p>Couleur et forme :LiquidMasse moléculaire :148.43 (kD)Azintuxizumab
CAS :<p>Azintuxizumab, an IgG4 bispecific antibody, targets BCMA, offering dual-action immunotherapy for relapsed/refractory multiple myeloma in preclinical studies.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidInezetamab
CAS :<p>Inezetamab is a bispecific anti- CD40 and anti- MSLN IgG1 monoclonal antibody [1] .</p>Degré de pureté :95% - 95%Couleur et forme :LiquidBleselumab
CAS :<p>Bleselumab (ASKP 1240) is a humanised monoclonal antibody targeting CD40, inhibiting immune responses, organ transplant rejection.</p>Degré de pureté :95%Couleur et forme :LiquidTabalumab
CAS :<p>Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.</p>Degré de pureté :95%Couleur et forme :LiquidIvuxolimab
CAS :<p>Ivuxolimab is a human IgG2 antibody that acts as an OX40 agonist, promoting T cell responses for anti-tumor immunity research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidCifurtilimab
CAS :<p>Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.</p>Degré de pureté :95%Couleur et forme :LiquidAfimkibart
CAS :<p>Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.</p>Degré de pureté :95% - 95%Couleur et forme :SoildRavagalimab
CAS :<p>Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidFrexalimab
CAS :<p>Frexalimab (SAR441344; INX-021), a monoclonal antibody that targets the CD40 ligand (CD40L), shows promise for research in multiple sclerosis [1].</p>Couleur et forme :LiquidAfelimomab
CAS :<p>Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].</p>Couleur et forme :LiquidTecaginlimab
CAS :<p>Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.</p>Couleur et forme :LiquidAnti-Mouse TNFR2 Antibody (TR75-54.7)
<p>Anti-Mouse TNFR2 Antibody is an Armenian Hamster-derived IgG inhibitor specifically targeting mouse TNFR2.</p>Couleur et forme :Odour LiquidIratumumab
CAS :<p>Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.</p>Couleur et forme :LiquidIA-14069
CAS :<p>IA-14069 is a TNF-a inhibitor with anti-inflammatory activity and pro-inflammatory cytokine production, and is used in the study of colon cancer.</p>Formule :C20H15ClF2O4Couleur et forme :SoildMasse moléculaire :392.78Cot inhibitor-2
CAS :<p>Cot inhibitor-2: Potent, selective Tpl2/MAP3K8 blocker. IC50: 1.6 nM; hampers LPS-induced TNF-α, IC50: 0.3 μM. Orally active.</p>Formule :C26H25Cl2FN8Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :539.43Selicrelumab
CAS :<p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>Degré de pureté :98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Couleur et forme :LiquidVU0285655-1
CAS :<p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>Formule :C25H27N5O2Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :429.51TNF-α-IN-1
CAS :<p>TNF-α-IN-1 is a TNF-α inhibitor.</p>Formule :C16H14ClN3O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :363.75UCB-5307
CAS :<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :343.42Cot inhibitor-1
CAS :<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formule :C27H27Cl2FN8Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :553.46Mitazalimab
CAS :<p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>Degré de pureté :95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidSPD304 dihydrochloride
CAS :<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53GSK2593074A
CAS :<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Formule :C27H23N5OSDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :465.57BMS-561392
CAS :<p>BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.</p>Formule :C27H32N4O4Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :476.57PK68
CAS :<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Formule :C22H24N4O3SDegré de pureté :98.09% - 99.64%Couleur et forme :SolidMasse moléculaire :424.52Trovafloxacin mesylate
CAS :<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Formule :C21H19F3N4O6SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :512.46C 87
CAS :<p>C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.</p>Formule :C24H15ClN6O3SDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :502.93Boserolimab
CAS :<p>Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.</p>Couleur et forme :LiquidCDC801
CAS :<p>CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.</p>Formule :C23H24N2O5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :408.45TNF-α-IN-2
CAS :<p>TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.</p>Formule :C25H21ClF2N6ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :494.92TNF-α-IN-14
CAS :<p>TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].</p>Formule :C22H26O6Couleur et forme :SolidMasse moléculaire :386.44TNF-α-IN-12
CAS :<p>TNF-α-IN-12, a TNF-α inhibitor with an IC50 of 0.1 μM, can reduce TNF-α blood levels [1].</p>Formule :C21H22O6Couleur et forme :SolidMasse moléculaire :370.4
