TNF
Les inhibiteurs du facteur de nécrose tumorale (TNF) sont des composés qui bloquent l'activité du TNF, une cytokine impliquée dans l'inflammation et la régulation de l'apoptose. Le TNF peut induire l'apoptose dans certains types cellulaires tout en favorisant la survie et l'inflammation dans d'autres. L'inhibition du TNF est cruciale dans le traitement des maladies auto-immunes, des affections inflammatoires chroniques et de certains cancers. Les inhibiteurs de TNF aident à moduler la réponse immunitaire et à réduire les dommages tissulaires causés par une inflammation excessive. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de TNF de haute qualité pour soutenir vos recherches en immunologie, inflammation et apoptose.
109 produits trouvés pour "TNF".
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(S,S)-TAPI-1 FA
(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.Formule :C27H39N5O7Degré de pureté :97.61% - 99.72%Couleur et forme :Yellow SolidMasse moléculaire :545.63Enavatuzumab
CAS :Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :150 kDaConatumumab
CAS :Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.44 kDaRuplizumab
CAS :PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.Degré de pureté :98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :145.42 kDaIscalimab
CAS :Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.Degré de pureté :>95%Couleur et forme :Transparent LiquidMasse moléculaire :146.08 kDaHS-243
CAS :HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.Formule :C17H16N4O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :324.33UCB-9260
CAS :UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.Formule :C26H25N5ODegré de pureté :98.39% - 99.24%Couleur et forme :White SolidMasse moléculaire :423.51Ref: TM-T13951
1mg92,00€2mg133,00€5mg219,00€1mL*10mM (DMSO)245,00€10mg353,00€25mg602,00€50mg802,00€100mg1.108,00€200mg1.485,00€Utomilumab
CAS :Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.Formule :C17H24N8O3Degré de pureté :95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :142.77 kDaTeneliximab
CAS :Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.Degré de pureté :99.19% (SEC-HPLC) - >95.0% (SDS-PAGE)Couleur et forme :LiquidMasse moléculaire :146.06 kDaOzoralizumab
CAS :Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.Degré de pureté :SDS-PAGE:> 95%;SEC-HPLC:95.6%Couleur et forme :Transparent LiquidMasse moléculaire :38.44 kDaLucatumumab
CAS :Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.Degré de pureté :95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :146.15 kDaDacetuzumab
CAS :Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.Degré de pureté :95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.1 kDaEU-102
EU-102 is a human monoclonal antibody (mAb) targeting TNFSF18. It is applicable for research in the field of solid tumors.Nerelimomab
CAS :Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].Couleur et forme :LiquidGiloralimab
CAS :Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.Degré de pureté :95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.34 kDaTulinercept
CAS :Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].Couleur et forme :LiquidBMS-986156
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody that targets the glucocorticoid-induced tumor necrosis factor receptor-related protein (GITR). It binds to GITR and enhances the activation of T effector cells while deactivating T regulatory cells. BMS-986156 is applicable for research in advanced solid tumors.Couleur et forme :Odour LiquidTQB2916
TQB2916 is a humanized IgG2 monoclonal antibody agonist that targets CD40. It exhibits significant antitumor activity by occupying CD40 and activating immune function. TQB2916 is applicable for research in advanced solid tumors and lymphomas.Couleur et forme :Odour LiquidGSK2800528
GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa, utilized for research related to inflammation and psoriasis.Couleur et forme :Odour LiquidPlaculumab
CAS :Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.Couleur et forme :LiquidVarlilumab
CAS :Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.65%Couleur et forme :LiquidMasse moléculaire :146 kDaSotigalimab
CAS :Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Degré de pureté :98.50% - 98.50%Couleur et forme :LiquidMasse moléculaire :144.35 kDaOnercept
CAS :Onercept, a recombinant soluble form of the human tumor necrosis factor-alpha (TNF-α) p55 receptor, is utilized in the study of Crohn's disease [1].Couleur et forme :LiquidZigakibart
CAS :Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)Degré de pureté :95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.03 kDaRO7567132
RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.Couleur et forme :Odour LiquidSym029
Sym029 is a human IgG monoclonal antibody (mAb) that targets TNFRSF5/CD40. It is applicable for cancer research. The suggested isotype control is Human IgG1 kappa, Isotype Control.Couleur et forme :Odour LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :150 kDaOnfekafusp alfa
CAS :Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Couleur et forme :LiquidPamlectabart
Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.20 kDaTengonermin
CAS :Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.Couleur et forme :LiquidDSTYSLSSTLTLSK TFA
DSTYSLSSTLTLSK TFA detects infliximab, a chimeric IgG1 antibody targeting TNF-α.Formule :C66H108F3N15O28Couleur et forme :SolidMasse moléculaire :1616.64Ragifilimab
CAS :Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :146.46 kDaXmAb-2513
XmAb-2513 is a humanized monoclonal antibody inhibitor targeting CD30. It demonstrates significant anti-proliferative activity along with excellent antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). XmAb-2513 is applicable in research on hematological malignancies such as Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL).Couleur et forme :Odour LiquidLenercept
CAS :Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Couleur et forme :LiquidTanfanercept
CAS :Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.Couleur et forme :LiquidTNF-α Antagonist
CAS :TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction withFormule :C58H71N11O15S2Couleur et forme :SolidMasse moléculaire :1226.39Ingitamig
Ingitamig is a dual-specificity antibody of the (G1_L-κ)_(G1-scFvkh_L-κ) type, targeting TNFRSF17/KLRK1.TNF-α (46-65), human
CAS :Human TNF alpha (46-65) peptide.Formule :C110H172N24O30Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2310.69Dazodalibep
CAS :Dazodalibep (MEDI 4920; VIB 4920) is a monoclonal antibody that specifically targets CD40LG/TNFSF5 and is fused to human serum albumin (ALB/HSA) [1].Couleur et forme :LiquidPegsunercept
CAS :Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Couleur et forme :LiquidBIIB023
BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.Couleur et forme :Odour LiquidAcetyl tetrapeptide-2
CAS :Acetyl tetrapeptide-2 is a skin conditioner, by soothing and nourishing the skin through similar mechanisms as other peptides.Formule :C26H39N5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :565.62Ranevetmab
CAS :Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Couleur et forme :LiquidKGYY15
CAS :KGYY15 (Mouse KGYY15), a peptide that targets CD40, exhibits weak inhibition of the CD40-CD40L interaction, with an IC50 exceeding 1 mM. At a concentration of 100 μM, KGYY15 activates the NF-κB pathway by 33%.Formule :C84H129N21O22SCouleur et forme :SolidMasse moléculaire :1817.12MK-4166
MK-4166 is a humanized IgG1 agonistic monoclonal antibody targeting GITR. It is capable of enhancing the proliferation of both naive T lymphocytes and tumor-infiltrating T lymphocytes.Couleur et forme :Odour LiquidEfaprinermin alfa
CAS :Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Couleur et forme :LiquidTilogotamab
CAS :Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :144.88 kDaTNF-α-IN-9
CAS :TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.Formule :C17H14O4Degré de pureté :99.21%Couleur et forme :SoildMasse moléculaire :282.29Aplitabart
Aplitabart is a humanized IgM-κ antibody targeting TNFRSF10B.Couleur et forme :Odour LiquidTelitacicept
CAS :Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligandCouleur et forme :Liquid
