TNF
Les inhibiteurs du facteur de nécrose tumorale (TNF) sont des composés qui bloquent l'activité du TNF, une cytokine impliquée dans l'inflammation et la régulation de l'apoptose. Le TNF peut induire l'apoptose dans certains types cellulaires tout en favorisant la survie et l'inflammation dans d'autres. L'inhibition du TNF est cruciale dans le traitement des maladies auto-immunes, des affections inflammatoires chroniques et de certains cancers. Les inhibiteurs de TNF aident à moduler la réponse immunitaire et à réduire les dommages tissulaires causés par une inflammation excessive. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de TNF de haute qualité pour soutenir vos recherches en immunologie, inflammation et apoptose.
92 produits trouvés pour "TNF"
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Dacetuzumab
CAS :<p>Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity for the study of recurrent diffuse large B-cell lymphoma.</p>Degré de pureté :95.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 95.4% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidTeneliximab
CAS :<p>Teneliximab (BMS 224819) is a chimeric monoclonal antibody that blocks CD40-CD40L interactions.Cost-effective and quality-assured.</p>Degré de pureté :95.00% - 99.19% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.06 kDaEnavatuzumab
CAS :<p>Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.</p>Degré de pureté :>95%Couleur et forme :LiquidUCB-9260
CAS :<p>UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.</p>Formule :C26H25N5ODegré de pureté :98.39% - 99.24%Couleur et forme :SolidMasse moléculaire :423.51Lucatumumab
CAS :<p>Lucatumumab (HCD122) is a fully human anti-CD40 monoclonal antibody with anti-tumor activity for the study of multiple myeloma.</p>Degré de pureté :95.5% (SDS-PAGE); 98.4% (SEC-HPLC) - 95.5% (SDS-PAGE); 98.4% (SEC-HPLC)Couleur et forme :LiquidCertolizumab pegol
CAS :<p>Certolizumab pegol (Certolizumab) is a polyethylene glycolized and humanized anti-TNF-α monoclonal antibody.</p>Degré de pureté :95% - 98.2% (SDS-PAGE); 99.1% (SEC-HPLC)Couleur et forme :LiquidRuplizumab
CAS :<p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>Degré de pureté :98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidUtomilumab
CAS :<p>Utomilumab, a humanized IgG2 against T-cell receptor 4-1BB/CD137, shows antitumor effects in advanced cancers.</p>Formule :C17H24N8O3Degré de pureté :95% - 95.1% (SDS-PAGE); 98.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :142.77 kDa(S,S)-TAPI-1 FA
<p>(S,S)-TAPI-1 FA is a TNF-α processing inhibitor with potential anti-inflammatory effects, blocks TACE, and can inhibit TNF-α signaling can be used to study Staphylococcus aureus arthritis.</p>Formule :C27H39N5O7Degré de pureté :97.61% - 99.72%Couleur et forme :SolidMasse moléculaire :545.63Ozoralizumab
CAS :<p>Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.</p>Degré de pureté :SDS-PAGE:> 95%;SEC-HPLC:95.6%Couleur et forme :LiquidMasse moléculaire :38.44 kDaConatumumab
CAS :<p>Conatumumab (AMG 655) targets DR5 to induce apoptosis in tumors, with Kd of 1 nM (long DR5) and 0.8 nM (short DR5).</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145 kDa (average)Iscalimab
CAS :<p>Iscalimab (CFZ-533) is a humanized monoclonal antibody targeting CD40, used in research on myasthenia gravis and Sjögren’s syndrome.</p>Degré de pureté :>95%Couleur et forme :LiquidVarlilumab
CAS :<p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.65%Couleur et forme :LiquidMasse moléculaire :146 kDaZigakibart
CAS :<p>Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)</p>Degré de pureté :95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Couleur et forme :LiquidRagifilimab
CAS :<p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :146.46 kDaCot inhibitor-1 hydrochloride
<p>Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.</p>Formule :C27H28Cl3FN8Degré de pureté :98.26%Couleur et forme :SoildMasse moléculaire :589.92TNF-α-IN-9
CAS :<p>TNF-α-IN-9 is an NDM-1 inhibitor-3 analog and is a TNF-α inhibitor.TNF-α-IN-9 shows low inhibitory activity.</p>Formule :C17H14O4Degré de pureté :98.28%Couleur et forme :SoildMasse moléculaire :282.29Anti-Mouse TNF α Antibody (TN3-19.12)
<p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>Degré de pureté :95% - ＞10mg/mlCouleur et forme :Odour LiquidRO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Couleur et forme :Odour LiquidPamlectabart
<p>Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.</p>Degré de pureté :95%Couleur et forme :Odour LiquidRelfovetmab
CAS :<p>Relfovetmab is an anti- NGF monoclonal antibody (mAb) [1] .</p>Couleur et forme :LiquidOnfekafusp alfa
CAS :<p>Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.</p>Couleur et forme :LiquidTengonermin
CAS :<p>Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.</p>Couleur et forme :LiquidPegsunercept
CAS :<p>Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].</p>Couleur et forme :LiquidNerelimomab
CAS :<p>Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].</p>Couleur et forme :LiquidAsunercept
CAS :<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Couleur et forme :LiquidTanfanercept
CAS :<p>Tanfanercept (HL036337) is an anti-TNF-α antibody, improving corneal erosions in dry eye mice.</p>Couleur et forme :LiquidPlaculumab
CAS :<p>Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.</p>Couleur et forme :LiquidRanevetmab
CAS :<p>Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.</p>Couleur et forme :LiquidLenercept
CAS :<p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>Couleur et forme :LiquidAtibuclimab
CAS :<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.28 kDaBIIB023
<p>BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.</p>Couleur et forme :Odour LiquidTNF-α Antagonist
CAS :<p>TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with</p>Formule :C58H71N11O15S2Couleur et forme :SolidMasse moléculaire :1226.39Giloralimab
CAS :<p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>Degré de pureté :95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Couleur et forme :LiquidSotigalimab
CAS :<p>Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.</p>Degré de pureté :98.50% - 98.50%Couleur et forme :LiquidDapirolizumab
<p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :145.5 kDaHS-243
CAS :<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formule :C17H16N4O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :324.33EJMC-1
CAS :<p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>Formule :C17H11ClN2O4SDegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :374.8Tilogotamab
CAS :<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Degré de pureté :95%Couleur et forme :LiquidTNF α Protein, Rabbit, Recombinant
<p>Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.</p>Degré de pureté :98% - > 99.9%Couleur et forme :Lyophilized PowderMasse moléculaire :18 KDa (reducing condition)TNF α Protein, Ferret, Recombinant (His)
<p>TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Cynomolgus, Recombinant (His)
<p>TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi)
<p>TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 57-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :18 KDa (reducing condition)TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
<p>TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (aa 77-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.</p>Degré de pureté :Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Couleur et forme :Lyophilized PowderMasse moléculaire :16 KDa (reducing condition)QNZ
CAS :<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Formule :C22H20N4ODegré de pureté :99.17% - 99.18%Couleur et forme :White SolidMasse moléculaire :356.42R-7050
CAS :<p>R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.</p>Formule :C16H8ClF3N4SDegré de pureté :98.64% - 99.8%Couleur et forme :SolidMasse moléculaire :380.77Hispidol
CAS :<p>Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colon</p>Formule :C15H10O4Degré de pureté :97.86% - 98.45%Couleur et forme :SolidMasse moléculaire :254.24Resatorvid
CAS :<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Formule :C15H17ClFNO4SDegré de pureté :99.31% - >99.99%Couleur et forme :SolidMasse moléculaire :361.82
