TNF
Les inhibiteurs du facteur de nécrose tumorale (TNF) sont des composés qui bloquent l'activité du TNF, une cytokine impliquée dans l'inflammation et la régulation de l'apoptose. Le TNF peut induire l'apoptose dans certains types cellulaires tout en favorisant la survie et l'inflammation dans d'autres. L'inhibition du TNF est cruciale dans le traitement des maladies auto-immunes, des affections inflammatoires chroniques et de certains cancers. Les inhibiteurs de TNF aident à moduler la réponse immunitaire et à réduire les dommages tissulaires causés par une inflammation excessive. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de TNF de haute qualité pour soutenir vos recherches en immunologie, inflammation et apoptose.
94 produits trouvés pour "TNF"
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BCMA72-80
CAS :BCMA72-80: HLA-A2-specific peptide with high affinity; used in multiple myeloma and other BCMA+ tumor research.Formule :C59H97N13O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1196.55Adalimumab β
CAS :Adalimumab beta (ABP-501) is an anti-TNF-α monoclonal antibody utilized in the study of rheumatoid arthritis (RA) [1].Couleur et forme :LiquidDapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :150 kDaHS-243
CAS :HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
Formule :C17H16N4O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :324.33TNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Degré de pureté :98% - > 99.9%Couleur et forme :Lyophilized PowderMasse moléculaire :18 KDa (reducing condition)TNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :18 KDa (reducing condition)Ref: TM-TMPJ-00125
5µg113,00€10µg178,00€20µg284,00€50µg523,00€100µg779,00€200µg1.142,00€500µg1.923,00€1mg2.758,00€TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Degré de pureté :Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Couleur et forme :Lyophilized PowderMasse moléculaire :16 KDa (reducing condition)Ref: TM-TMPJ-00124
5µg42,00€10µg59,00€20µg87,00€50µg130,00€100µg210,00€200µg354,00€500µg709,00€1mg1.017,00€TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00121
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€TNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Degré de pureté :> 90% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 90% as determined by Bis-Tris PAGE > 95% as determined by HPLCCouleur et forme :Lyophilized PowderMasse moléculaire :20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :18.88 kDa (predicted) same as Tris-Bis PAGE result.Hispidol
CAS :Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFormule :C15H10O4Degré de pureté :97.86% - 98.45%Couleur et forme :SolidMasse moléculaire :254.24Ref: TM-T4319
1mg42,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg137,00€25mg200,00€50mg260,00€100mg409,00€200mg560,00€500mg954,00€LASSBio-1135
CAS :LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.Formule :C18H14N4Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :286.33Roquinimex
CAS :Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFormule :C18H16N2O3Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :308.33STING-IN-2
CAS :STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Formule :C15H16N2O4Degré de pureté :98.61%Couleur et forme :SolidMasse moléculaire :288.3R-7050
CAS :R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formule :C16H8ClF3N4SDegré de pureté :98.64% - 99.8%Couleur et forme :SolidMasse moléculaire :380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)71,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€N-Formyl-Met-Leu-Phe
CAS :N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Formule :C21H31N3O5SDegré de pureté :98.69% - 98.69%Couleur et forme :SolidMasse moléculaire :437.55UTL-5g
CAS :UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.Formule :C11H8Cl2N2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :271.1Ref: TM-T8845
2mgÀ demander5mg66,00€1mL*10mM (DMSO)73,00€10mg94,00€25mg182,00€50mg258,00€100mg366,00€(Rac)-Benpyrine
CAS :(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Formule :C16H16N6ODegré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€Tulisokibart
CAS :Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Degré de pureté :98.38% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :143.96 kDaTavolixizumab
CAS :Tavolixizumab (also known as MEDI 0562 and Tavolimab) is a human monoclonal antibody targeting TNFRSF4 (TNF receptor superfamily member 4), utilized in cancerCouleur et forme :LiquidLicaminlimab
Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.Couleur et forme :Odour LiquidTecaginlimab
CAS :Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.Couleur et forme :LiquidAfimkibart
CAS :Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.Degré de pureté :95% - 99.2% (SDS-PAGE); 95.3% (SEC-HPLC)Couleur et forme :SoildMasse moléculaire :146.20 kDaAfelimomab
CAS :Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].Couleur et forme :LiquidTabalumab
CAS :Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :146.24 kDaDalnicastobart
CAS :Dalnicastobart (LVGN-7409) is a humanized monoclonal antibody targeting CD40/TNFRSF5 with agonist activity, immunostimulatory and antitumor.Degré de pureté :95% - 97.4% (SDS-PAGE); 97.8% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.33 kDaIratumumab
CAS :Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Couleur et forme :LiquidToralizumab
CAS :Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.Couleur et forme :LiquidMasse moléculaire :148.43 (kD)Cifurtilimab
CAS :Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.10 kDaRavagalimab
CAS :Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.Degré de pureté :95% - 96.9% (SDS-PAGE); 99.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.95 kDaTNF-α-IN-1
CAS :TNF-α-IN-1 is a TNF-α inhibitor.Formule :C16H14ClN3O5Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :363.75Ref: TM-T13175
1mg56,00€5mg120,00€10mg178,00€1mL*10mM (DMSO)203,00€25mg330,00€50mg505,00€100mg713,00€Selicrelumab
CAS :Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Degré de pureté :98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.2 kDaUCB-5307
CAS :UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :343.42SPD304 dihydrochloride
CAS :SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53Mitazalimab
CAS :Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Degré de pureté :95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.42 kDaTrovafloxacin mesylate
CAS :Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formule :C21H19F3N4O6SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :512.46BMS-561392
CAS :BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.Formule :C27H32N4O4Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :476.57PK68
CAS :PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.Formule :C22H24N4O3SDegré de pureté :98.09% - 99.64%Couleur et forme :SolidMasse moléculaire :424.52Ref: TM-T12493
1mg77,00€5mg166,00€1mL*10mM (DMSO)178,00€10mg260,00€25mg492,00€50mg708,00€100mg888,00€C 87
CAS :C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.Formule :C24H15ClN6O3SDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :502.93CDC801
CAS :CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.
Formule :C23H24N2O5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :408.45TNF-α-IN-14
CAS :TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].Formule :C22H26O6Couleur et forme :SolidMasse moléculaire :386.44TNF-α-IN-2
CAS :TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.Formule :C25H21ClF2N6ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :494.92TNF-α-IN-12
CAS :TNF-α-IN-12, a TNF-α inhibitor with an IC50 of 0.1 μM, can reduce TNF-α blood levels [1].Formule :C21H22O6Couleur et forme :SolidMasse moléculaire :370.4
