TNF
Les inhibiteurs du facteur de nécrose tumorale (TNF) sont des composés qui bloquent l'activité du TNF, une cytokine impliquée dans l'inflammation et la régulation de l'apoptose. Le TNF peut induire l'apoptose dans certains types cellulaires tout en favorisant la survie et l'inflammation dans d'autres. L'inhibition du TNF est cruciale dans le traitement des maladies auto-immunes, des affections inflammatoires chroniques et de certains cancers. Les inhibiteurs de TNF aident à moduler la réponse immunitaire et à réduire les dommages tissulaires causés par une inflammation excessive. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de TNF de haute qualité pour soutenir vos recherches en immunologie, inflammation et apoptose.
109 produits trouvés pour "TNF".
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Afimkibart
CAS :Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.Degré de pureté :95% - 99.2% (SDS-PAGE); 95.3% (SEC-HPLC)Couleur et forme :SoildMasse moléculaire :146.20 kDaTabalumab
CAS :Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :146.24 kDaIratumumab
CAS :Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Couleur et forme :LiquidDalnicastobart
CAS :Dalnicastobart (LVGN-7409) is a humanized monoclonal antibody targeting CD40/TNFRSF5 with agonist activity, immunostimulatory and antitumor.Degré de pureté :95% - 97.4% (SDS-PAGE); 97.8% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :146.33 kDaAfelimomab
CAS :Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].Couleur et forme :LiquidTecaginlimab
CAS :Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.Couleur et forme :LiquidAnti-Mouse CD40 Antibody (FGK4.5/FGK45)
Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a rat-derived IgG2a monoclonal antibody targeting mouse CD40, a type I transmembrane glycoprotein within the tumor necrosis factor receptor (TNFR) superfamily. CD40 functions as a costimulatory molecule, activating B cells, dendritic cells, monocytes, and other antigen-presenting cells (APC), thereby enhancing antitumor T cell responses.Couleur et forme :Odour LiquidAnti-Mouse TNF-α/TNFSF2 Antibody (XT3.11)
The Anti-Mouse?TNF-alpha/TNFSF2 Antibody (XT3.11) is a rat-derived IgG1 monoclonal antibody targeting TNF-alpha/TNFSF2. The isotype control for this product is RatIgG1kappa, Isotype Control.Licaminlimab
Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.Couleur et forme :Odour LiquidAnti-Mouse TNFR2 Antibody (TR75-54.7)
Anti-Mouse TNFR2 Antibody (TR75-54.7) is a monoclonal antibody that reduces white blood cell counts and decreases pro-inflammatory cytokine expression.Couleur et forme :Transparent LiquidMasse moléculaire :~150 kDaBleselumab
CAS :Bleselumab (ASKP 1240) is a humanised monoclonal antibody targeting CD40, inhibiting immune responses, organ transplant rejection.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :144.16 kDaCifurtilimab
CAS :Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.Degré de pureté :95%Couleur et forme :Transparent LiquidMasse moléculaire :145.10 kDaRavagalimab
CAS :Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.Degré de pureté :95% - 96.9% (SDS-PAGE); 99.5% (SEC-HPLC)Couleur et forme :Transparent LiquidMasse moléculaire :145.95 kDaAnti-Mouse TL1A/TNFSF15 Antibody (5G4.6)
Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6) is an IgG antibody inhibitor derived from the American hamster, specifically targeting the mouse TL1A/TNFSF15.Couleur et forme :Odour LiquidSelicrelumab
CAS :Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Degré de pureté :98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.2 kDaTNF-α-IN-1
CAS :TNF-α-IN-1 is a TNF-α inhibitor.Formule :C16H14ClN3O5Degré de pureté :98.82%Couleur et forme :Brown SolidMasse moléculaire :363.75Ref: TM-T13175
1mg56,00€5mg120,00€10mg178,00€1mL*10mM (DMSO)203,00€25mg330,00€50mg505,00€100mg713,00€Mitazalimab
CAS :Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Degré de pureté :95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.42 kDaUCB-5307
CAS :UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :White SolidMasse moléculaire :343.42SPD304 dihydrochloride
CAS :SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53Ref: TM-T12985
1mg63,00€5mg137,00€1mL*10mM (DMSO)178,00€10mg205,00€25mg430,00€50mg620,00€100mg883,00€Trovafloxacin mesylate
CAS :Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Formule :C21H19F3N4O6SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :512.46
