IAP
Les inhibiteurs de protéines inhibitrices de l'apoptose (IAP) sont des composés qui bloquent l'activité des IAP, une famille de protéines qui empêchent l'apoptose en inhibant les caspases et d'autres composants de la machinerie apoptotique. Les inhibiteurs d'IAP favorisent l'apoptose dans les cellules cancéreuses en neutralisant ces signaux de survie, ce qui en fait des outils importants dans la recherche sur le cancer et la thérapie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs d'IAP de haute qualité pour soutenir vos recherches en oncologie, apoptose et développement thérapeutique.
67 produits trouvés pour "IAP"
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MV1
CAS :MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.Formule :C33H44N4O5Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :576.73Ref: TM-T16163
2mg44,00€5mg67,00€1mL*10mM (DMSO)86,00€10mg112,00€25mg187,00€50mg280,00€100mg396,00€200mg522,00€SBP-0636457
CAS :SBP-0636457: SMAC mimetic, IAP inhibitor, binds BIR-domains (Ki=0.27μM), potential in tumor/cancer research.Formule :C25H36N4O4Couleur et forme :SolidMasse moléculaire :456.587SM-164 Hydrochloride (957135-43-2 free base)
SM-164 Hydrochloride: cell-permeable, binds to XIAP (BIR2/3 domains), IC50 of 1.39 nM, potent XIAP antagonist.Formule :C62H85ClN14O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1157.88CST626
CAS :CST626 is a PROTAC degrader that targets XIAP, cIAP1, and cIAP2.Formule :C61H82N8O9SDegré de pureté :95.87%Couleur et forme :SolidMasse moléculaire :1103.42XIAP BIR2/BIR2-3 inhibitor-1
CAS :XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) serves as a potent dual inhibitor targeting BIR2 and BIR2-3 domains, with IC50 values of 1.9 nM and 0.8 nM, respectively. This compound is utilized in cancer research studies [1].Formule :C72H96N16O14Couleur et forme :SolidMasse moléculaire :1409.63S2/IAPinh
S2/IAPinh is a conjugate composed of an inhibitor of apoptosis proteins inhibitor (IAPinh) and a ligand of sigma 2 SW43. It demonstrates anti-proliferative and apoptosis-inducing activity by degrading inhibitor of apoptosis proteins (clAP-1).Formule :C52H75Cl2FN6O6SMasse moléculaire :1000.48299XIAP BIR2/BIR2-3 inhibitor-3
CAS :XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].Formule :C86H106N18O16S2Couleur et forme :SolidMasse moléculaire :1712MDM2/XIAP-IN-1
MDM2/XIAP-IN-1 (compound 14) is an orally active dual inhibitor of MDM2 and XIAP, exhibiting anti-cancer activity with an IC50 of 0.3 μM and potentialCouleur et forme :Odour SolidAnti-CD47 Antibody (8A121)
Anti-CD47 Antibody (8A121) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (8A121) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CD47 Antibody (8K78)
Anti-CD47 Antibody (8K78) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (8K78) can be used in WB,ELISA,IP.Couleur et forme :Odour LiquidAnti-CD47 Antibody (4E249)
Anti-CD47 Antibody (4E249) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (4E249) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CD47 Antibody (5R542)
Anti-CD47 Antibody (5R542) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5R542) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CD47 Antibody (5K435)
Anti-CD47 Antibody (5K435) is an antibody targeting CD47. Anti-CD47 Antibody (5K435) can be used in ELISA, WB, IHC, IF.Couleur et forme :Odour LiquidAnti-CD47 Antibody-PE (9X161)
Anti-CD47 Antibody-PE (9X161) is a PE-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-PE (9X161) can be used in FCM.Couleur et forme :Odour LiquidAnti-CD47 Antibody (5S892)
Anti-CD47 Antibody (5S892) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (5S892) can be used in IHC-P.Couleur et forme :Odour LiquidAnti-CD47 Antibody (9X161)
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.Couleur et forme :Odour LiquidAnti-CD47 Antibody-FITC (9X161)
Anti-CD47 Antibody-FITC (9X161) is a FITC-conjugated Mouse antibody targeting CD47. Anti-CD47 Antibody-FITC (9X161) can be used in FCM.Couleur et forme :Odour LiquidAnti-CD47 Antibody (4C168)
Anti-CD47 Antibody (4C168) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (4C168) can be used in IHC-P.Couleur et forme :Odour LiquidAnti-CD47 Antibody (6T428)
Anti-CD47 Antibody (6T428) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (6T428) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CD47 Antibody (5E321)
Anti-CD47 Antibody (5E321) is a Rabbit antibody targeting CD47. Anti-CD47 Antibody (5E321) can be used in ELISA.Couleur et forme :Odour LiquidAnti-CD47 Antibody (1F304)
Anti-CD47 Antibody (1F304) is an antibody targeting CD47. Anti-CD47 Antibody (1F304) can be used in ELISA, FCM.Couleur et forme :Odour LiquidAZD5582
CAS :AZD5582 is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. It induces apoptosis.Formule :C58H78N8O8Degré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :1015.29CD47 Protein, Mouse, Recombinant (His)
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :SDS-PAGE: 98.3%; SEC-HPLC: 98.5%Couleur et forme :Lyophilized PowderMasse moléculaire :15.3 kDa (predicted); 34-44 kDa (reducing condition, due to glycosylation)Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and isDegré de pureté :92.7%Couleur et forme :Lyophilized PowderMasse moléculaire :54.1 kDa (predicted); 66 kDa (reducing conditions)Ref: TM-TMPY-00570
5µg84,00€10µg119,00€20µg191,00€50µg376,00€100µg654,00€200µg1.151,00€500µg2.350,00€CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag.Couleur et forme :Lyophilized PowderMasse moléculaire :30-40 KDa (reducing condition)CD47 Protein, Human, Recombinant (hFc)
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Degré de pureté :> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCCouleur et forme :Lyophilized PowderMasse moléculaire :40.5 kDa (predicted); 55-65 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-03883
5µg50,00€10µg80,00€20µg114,00€50µg219,00€100µg421,00€200µg622,00€500µg1.324,00€1mg2.673,00€CD47 Protein, Human, Recombinant (mFc)
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :48-65 KDa (reducing condition)Ref: TM-TMPJ-00212
5µg56,00€10µg88,00€20µg118,00€50µg200,00€100µg358,00€200µg643,00€500µg1.414,00€1mg2.457,00€CD47 Protein, Human, Recombinant (aa 19-139, His)
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag.Couleur et forme :Lyophilized PowderMasse moléculaire :14.5 kDa (predicted); 40-55 kDa (reducing conditions)Ref: TM-TMPY-06367
5µg77,00€10µg112,00€20µg177,00€50µg351,00€100µg680,00€200µg1.018,00€500µg2.152,00€1mg4.393,00€Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalCouleur et forme :Lyophilized PowderMasse moléculaire :54.5 kDa (predicted). Due to glycosylation, the protein migrates to 63-73 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00796
5µg77,00€10µg109,00€20µg173,00€50µg337,00€100µg557,00€200µg1.007,00€500µg2.164,00€Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletalCouleur et forme :Lyophilized PowderMasse moléculaire :53.10 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :17.1 kDa (predicted); 38.8 kDa (reducing conditions)Alkaline phosphatase/ALPI Protein, Human, Recombinant (hFc)
Alkaline phosphatase Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :79.5 kDa (predicted); 90-95 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (aa 1-139, His)
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :SDS-PAGE: 98.4%; SEC-HPLC: 97.6%Couleur et forme :Lyophilized PowderMasse moléculaire :15.2 kDa (predicted); 35-44 kDa (reducing condition, due to glycosylation)CD47 Protein, Human, Recombinant (His)
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.Degré de pureté :Greater than 95% as determined by reducing SDS-PAGE. - SDS-PAGE: 100%; SEC-HPLC: 97%Couleur et forme :Lyophilized PowderMasse moléculaire :30-45 KDa (reducing condition)CD47 Protein, Human, Recombinant, Biotinylated
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells.Degré de pureté :97.6%Couleur et forme :Lyophilized PowderMasse moléculaire :14.5 kDa (predicted)CD47 Protein, Mouse, Recombinant
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371.Couleur et forme :Lyophilized PowderMasse moléculaire :13.8 kDa (predicted)CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Couleur et forme :Lyophilized PowderMasse moléculaire :15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Degré de pureté :97.8%Couleur et forme :Lyophilized PowderMasse moléculaire :14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Degré de pureté :98.4%Couleur et forme :Lyophilized PowderMasse moléculaire :54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-02650
5µg84,00€10µg119,00€20µg191,00€50µg376,00€100µg633,00€200µg1.075,00€500µg2.108,00€CD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :39.9 kDa (predicted)Polygalacin D
CAS :Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormule :C57H92O27Degré de pureté :98.95% - ≥98%Couleur et forme :SolidMasse moléculaire :1209.4GDC-0152
CAS :GDC-0152 is a potent inhibitor of IAPs.Formule :C25H34N6O3SDegré de pureté :97.18% - 99.32%Couleur et forme :SolidMasse moléculaire :498.64Birinapant
CAS :Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormule :C42H56F2N8O6Degré de pureté :97.08% - ≥95%Couleur et forme :SolidMasse moléculaire :806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€4-Methylsalicylic acid
CAS :4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formule :C8H8O3Degré de pureté :99.64%Couleur et forme :Solid Solid CrystallineMasse moléculaire :152.15SM-164
CAS :SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formule :C62H84N14O6Degré de pureté :98.53% - 99.92%Couleur et forme :SolidMasse moléculaire :1121.42MX69
CAS :MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formule :C27H26N2O4SDegré de pureté :97.27% - 99.57%Couleur et forme :SolidMasse moléculaire :474.57Ref: TM-T3653
2mg39,00€5mg58,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg167,00€50mg260,00€100mg409,00€200mg590,00€BV6
CAS :BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formule :C70H96N10O8Degré de pureté :97.46% - 99.82%Couleur et forme :SolidMasse moléculaire :1205.57Ref: TM-T6428
1mg49,00€2mg64,00€5mg89,00€10mg144,00€1mL*10mM (DMSO)178,00€25mg285,00€50mg537,00€100mg767,00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formule :C60H82N8O10Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :1075.36Xevinapant
CAS :Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formule :C32H43N5O4Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :561.71Ref: TM-T6763
1mg40,00€2mg54,00€5mg88,00€10mg124,00€1mL*10mM (DMSO)138,00€25mg260,00€50mg416,00€100mg647,00€200mg954,00€ASTX660
CAS :Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formule :C30H42FN5O3Degré de pureté :98.33% - 99.85%Couleur et forme :SolidMasse moléculaire :539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€LCL161
CAS :LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formule :C26H33FN4O3SDegré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :500.63Isolinderalactone
CAS :Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formule :C15H16O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :244.29Embelin
CAS :Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :60-70 KDa (reducing condition)CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :60-90 KDa (reducing condition)Ref: TM-TMPJ-00613
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Couleur et forme :Lyophilized PowderMasse moléculaire :33-55 KDa (reducing condition)Ref: TM-TMPJ-00614
5µg92,00€10µg149,00€20µg231,00€50µg439,00€100µg682,00€200µg1.063,00€500µg1.918,00€1mg2.890,00€MDM2/XIAP-IN-3
CAS :MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormule :C29H30N2O5SCouleur et forme :SolidMasse moléculaire :518.62A 410099.1
CAS :A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1T-3256336
CAS :T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formule :C31H45F2N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.72MX107
CAS :MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49NOC-5
CAS :NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.Formule :C6H16N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :176.22CUDC-427
CAS :CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formule :C29H36N6O4SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :564.7Anticancer agent 128
CAS :Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19Formule :C26H38N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.6Anticancer agent 127
CAS :Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,Formule :C26H37FN4O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :552.66XIAP/cIAP1 antagonist-1
Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.Couleur et forme :SolidXIAP degrader-1
XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).Formule :C34H45N5O4Couleur et forme :SolidMasse moléculaire :587.75
