IAP
Les inhibiteurs de protéines inhibitrices de l'apoptose (IAP) sont des composés qui bloquent l'activité des IAP, une famille de protéines qui empêchent l'apoptose en inhibant les caspases et d'autres composants de la machinerie apoptotique. Les inhibiteurs d'IAP favorisent l'apoptose dans les cellules cancéreuses en neutralisant ces signaux de survie, ce qui en fait des outils importants dans la recherche sur le cancer et la thérapie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs d'IAP de haute qualité pour soutenir vos recherches en oncologie, apoptose et développement thérapeutique.
67 produits trouvés pour "IAP"
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CD47 Protein, Mouse, Recombinant (rFc)
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :39.9 kDa (predicted)Polygalacin D
CAS :Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFormule :C57H92O27Degré de pureté :98.95% - ≥98%Couleur et forme :SolidMasse moléculaire :1209.4GDC-0152
CAS :GDC-0152 is a potent inhibitor of IAPs.Formule :C25H34N6O3SDegré de pureté :97.18% - 99.32%Couleur et forme :SolidMasse moléculaire :498.64Birinapant
CAS :Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFormule :C42H56F2N8O6Degré de pureté :97.08% - ≥95%Couleur et forme :SolidMasse moléculaire :806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€4-Methylsalicylic acid
CAS :4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Formule :C8H8O3Degré de pureté :99.64%Couleur et forme :Solid Solid CrystallineMasse moléculaire :152.15SM-164
CAS :SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Formule :C62H84N14O6Degré de pureté :98.53% - 99.92%Couleur et forme :SolidMasse moléculaire :1121.42MX69
CAS :MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Formule :C27H26N2O4SDegré de pureté :97.27% - 99.57%Couleur et forme :SolidMasse moléculaire :474.57Ref: TM-T3653
2mg39,00€5mg58,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg167,00€50mg260,00€100mg409,00€200mg590,00€BV6
CAS :BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Formule :C70H96N10O8Degré de pureté :97.46% - 99.82%Couleur et forme :SolidMasse moléculaire :1205.57Ref: TM-T6428
1mg49,00€2mg64,00€5mg89,00€10mg144,00€1mL*10mM (DMSO)178,00€25mg285,00€50mg537,00€100mg767,00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formule :C60H82N8O10Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :1075.36Xevinapant
CAS :Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Formule :C32H43N5O4Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :561.71Ref: TM-T6763
1mg40,00€2mg54,00€5mg88,00€10mg124,00€1mL*10mM (DMSO)138,00€25mg260,00€50mg416,00€100mg647,00€200mg954,00€ASTX660
CAS :Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formule :C30H42FN5O3Degré de pureté :98.33% - 99.85%Couleur et forme :SolidMasse moléculaire :539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€LCL161
CAS :LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Formule :C26H33FN4O3SDegré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :500.63Isolinderalactone
CAS :Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Formule :C15H16O3Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :244.29Embelin
CAS :Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Couleur et forme :Lyophilized PowderMasse moléculaire :60-70 KDa (reducing condition)CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Couleur et forme :Lyophilized PowderMasse moléculaire :60-90 KDa (reducing condition)Ref: TM-TMPJ-00613
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Couleur et forme :Lyophilized PowderMasse moléculaire :33-55 KDa (reducing condition)Ref: TM-TMPJ-00614
5µg92,00€10µg149,00€20µg231,00€50µg439,00€100µg682,00€200µg1.063,00€500µg1.918,00€1mg2.890,00€MDM2/XIAP-IN-3
CAS :MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressingFormule :C29H30N2O5SCouleur et forme :SolidMasse moléculaire :518.62A 410099.1
CAS :A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1T-3256336
CAS :T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Formule :C31H45F2N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.72
