IAP
Les inhibiteurs de protéines inhibitrices de l'apoptose (IAP) sont des composés qui bloquent l'activité des IAP, une famille de protéines qui empêchent l'apoptose en inhibant les caspases et d'autres composants de la machinerie apoptotique. Les inhibiteurs d'IAP favorisent l'apoptose dans les cellules cancéreuses en neutralisant ces signaux de survie, ce qui en fait des outils importants dans la recherche sur le cancer et la thérapie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs d'IAP de haute qualité pour soutenir vos recherches en oncologie, apoptose et développement thérapeutique.
66 produits trouvés pour "IAP"
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CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
<p>CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
<p>CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :40.6 kDa (predicted)CD47 Protein, Human, Recombinant
<p>CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.</p>Degré de pureté :97.8%Couleur et forme :Lyophilized PowderMasse moléculaire :14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase Protein, Human, Recombinant (His)
<p>Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Degré de pureté :98.4%Couleur et forme :Lyophilized PowderMasse moléculaire :54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Embelin
CAS :<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39GDC-0152
CAS :<p>GDC-0152 is a potent inhibitor of IAPs.</p>Formule :C25H34N6O3SDegré de pureté :97.18% - 99.32%Couleur et forme :SolidMasse moléculaire :498.64Birinapant
CAS :<p>Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor of</p>Formule :C42H56F2N8O6Degré de pureté :97.08% - ≥95%Couleur et forme :SolidMasse moléculaire :806.94ASTX660
CAS :<p>Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.</p>Formule :C30H42FN5O3Degré de pureté :98.33% - 99.85%Couleur et forme :SolidMasse moléculaire :539.68Xevinapant
CAS :<p>Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.</p>Formule :C32H43N5O4Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :561.71LCL161
CAS :<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Formule :C26H33FN4O3SDegré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :500.63Isolinderalactone
CAS :<p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>Formule :C15H16O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :244.29Polygalacin D
CAS :<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Formule :C57H92O27Degré de pureté :98.95% - ≥98%Couleur et forme :SolidMasse moléculaire :1209.44-Methylsalicylic acid
CAS :<p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>Formule :C8H8O3Degré de pureté :99.64%Couleur et forme :Solid Solid CrystallineMasse moléculaire :152.15SM-164
CAS :<p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>Formule :C62H84N14O6Degré de pureté :98.53% - 99.92%Couleur et forme :SolidMasse moléculaire :1121.42MX69
CAS :<p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>Formule :C27H26N2O4SDegré de pureté :97.27% - 99.57%Couleur et forme :SolidMasse moléculaire :474.57BV6
CAS :<p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>Formule :C70H96N10O8Degré de pureté :97.46% - 99.82%Couleur et forme :SolidMasse moléculaire :1205.57AZD5582 acetate (1258392-53-8 free base)
<p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>Formule :C60H82N8O10Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :1075.36T-3256336
CAS :<p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>Formule :C31H45F2N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :605.72MX107
CAS :<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Formule :C24H28N2O2Couleur et forme :SolidMasse moléculaire :376.49A 410099.1
CAS :<p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>Formule :C27H41ClN4O3Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :505.1
