Kinésine
Les inhibiteurs de kinésine ciblent les protéines motrices kinésines, responsables du transport des cargaisons cellulaires le long des microtubules et jouant un rôle clé dans la division cellulaire, en particulier pendant la mitose. Les kinésines sont impliquées dans le mouvement des chromosomes et d'autres organites pendant la division cellulaire. Inhiber les kinésines peut perturber ces processus, entraînant un arrêt du cycle cellulaire et une mort cellulaire potentielle, ce qui rend ces inhibiteurs précieux dans la recherche sur le cancer. Chez CymitQuimica, nous offrons une gamme diversifiée d'inhibiteurs de kinésine de haute qualité pour soutenir vos recherches en biologie cellulaire, mitose et thérapie contre le cancer.
89 produits trouvés pour "Kinésine".
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Mitotic kinesin-IN-1 hydrochloride
CAS :Mitotic kinesin-IN-1 hydrochloride (Example 80) is an inhibitor of mitotic kinesin, which suppresses cell proliferation by hindering mitosis. This compound is applicable in research related to cancer, cardiac hypertrophy, immune and inflammatory diseases, and fungal infections.Formule :C22H26ClF2N3OSCouleur et forme :SolidMasse moléculaire :453.98RMS-07
CAS :RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.Formule :C35H40N8O2Couleur et forme :SolidMasse moléculaire :604.74EX05
CAS :EX05, an effective KIF18A inhibitor, exhibits an IC50 of 8.2 nM and holds potential for cancer research applications.Formule :C26H30F2N4O5SCouleur et forme :SolidMasse moléculaire :548.60MKLP2-IN-1
CAS :MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.Formule :C23H19BrFN3O2Couleur et forme :SolidMasse moléculaire :468.318KIF18A-IN-18
CAS :KIF18A-IN-18 (Compound I) serves as an inhibitor of KIF18A and is applicable in studies of tumors characterized by chromosomal instability.Formule :C29H34F2N4O5SMasse moléculaire :588.67CCT368772
CAS :CCT368772 (compound 35) is a selective inhibitor of the kinesin protein HSET, with an HSET ADP-GloIC50 of 0.019 μM. It demonstrates specificity for HSET over Eg5, as shown by an Eg5 ADP-GloIC50 value greater than 200 μM. CCT368772 (compound 152) can be utilized in the study of hyperproliferative diseases and disorders such as cancer.Formule :C25H32N6O5SMasse moléculaire :528.63AM-9022
CAS :AM-9022 is a potent and selective KIF18A inhibitor, orally active and suitable for cancer research [1].Formule :C27H36F2N6O4SCouleur et forme :SolidMasse moléculaire :578.67TTK inhibitor 4
CAS :TTK inhibitor 4 (compound 16) acts as a potent threonine tyrosine kinase (TTK) inhibitor, exhibiting an IC 50 value of 0.016 μM and demonstrating anti-tumor activity [1].Formule :C25H29N9OCouleur et forme :SolidMasse moléculaire :471.56Cenpemlin
CAS :Cenpemlin is a CENP-M inhibitor that disrupts the interaction between CENP-M and CENP-L. It is useful for studying centromere-kinetochore interactions and the dynamic assembly of kinetochores during cell division.Formule :C17H29N7O7Masse moléculaire :443.46
