Intégrine
Les inhibiteurs d'intégrines ciblent les intégrines, une famille de récepteurs de surface cellulaire qui jouent un rôle crucial dans l'adhésion cellulaire, la migration et la transduction du signal. Les intégrines sont impliquées dans la régulation du cycle cellulaire, en particulier dans des processus tels que la division et la différenciation cellulaires. Inhiber les intégrines peut perturber ces processus, entraînant un arrêt du cycle cellulaire et l'apoptose, ce qui rend ces inhibiteurs précieux dans la recherche sur le cancer et l'étude des métastases. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs d'intégrines de haute qualité pour soutenir vos recherches sur la régulation du cycle cellulaire, la biologie du cancer et le développement thérapeutique.
278 produits trouvés pour "Intégrine"
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REDV TFA
REDV TFA, the minimal active sequence of the CS5 site in the alternatively spliced type III connecting segment (IIICS) of fibronectin, mediates adhesion to theFormule :C20H35N7O9·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :517.53 (free acid)HB-3-20
HB-3-20 induces the degradation of integrin αVβ5 on the cell surface. Transglutaminase 2 (TG2) specifically interacts with HB-3-20, exhibiting a catalytic efficiency (kcat/KM) of 0.16 μM^-1min^-1.Formule :C69H102N20O20Couleur et forme :SolidMasse moléculaire :1531.67Cyclo(Gly-Arg-Gly-Asp-Ser-Pro)
CAS :Cyclo(Gly-Arg-Gly-Asp-Ser-Pro) (c(GRGDSP)) is an RGD-containing inhibitory peptide and a synthetic α5β1 integrin ligand.Formule :C22H35N9O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :569.57FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro
CAS :FITC-Ahx-Gly-Arg-Gly-Asp-Ser-Pro, also known as FITC-linked GRGDSP, is a fluorescent peptide with integrin inhibitory properties.Formule :C49H59N11O16SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1090.12LXW7 TFA (1313004-77-1 free base)
LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an anti-inflammatory effect.Formule :C31H49F3N12O14S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :934.92JNJ-69086420
JNJ-69086420 (JNJ69086420) is a humanized antibody targeting human kininogenase-2 conjugated with Actinium-225, which can be used to study prostate cancer.Couleur et forme :LiquidMasse moléculaire :145.30 kDacRGDfK-thioacetyl ester
CAS :cRGDfK-thioacetyl ester, a bioactive polypeptide, exhibits selective affinity for integrins and can modify near-infrared (NIR) fluorescent probes for targetedFormule :C31H45N9O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :719.81Surovatamig
Surovatamig is a bispecific antibody of the (H-γ4_L-κ)_VH-G4(h-CH2-CH3) type, targeting CD3D/CD3E/CD19.Couleur et forme :Odour LiquidCatumaxomab
CAS :Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :146.73 kDaOdulimomab
CAS :Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.Couleur et forme :LiquidEtrolizumab
CAS :MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.Degré de pureté :98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.1 kDaAnti-Mouse CD3E Antibody (1E11.D)
Anti-Mouse CD3E Antibody (1E11.D) is an IgG1 antibody inhibitor targeting the mouse CD3E molecule.Couleur et forme :Odour LiquidCyclo(RGDfC) TFA
Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.Formule :C26H35F3N8O9SDegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :692.67Besufetamig
CAS :Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.Couleur et forme :LiquidMSH-TP15e
MSH-TP15e is a human-derived monoclonal antibody inhibitor that targets intercellular adhesion molecule-1 (ICAM-1). By recruiting natural killer cells, MSH-TP15e significantly induces antibody-dependent cell-mediated cytotoxicity (ADCC) activity, thereby inhibiting tumor cell growth. MSH-TP15e shows potential for research in multiple myeloma (MM).Couleur et forme :Odour LiquidGS-1427
CAS :GS-1427, Integrin α4β7 antagonist, for studying α4β7-mediated diseases like inflammatory bowel disease (IBD).Formule :C35H32F4N6O6Degré de pureté :99.05% - 99.65%Couleur et forme :SoildMasse moléculaire :708.66Ertumaxomab
CAS :Ertumaxomab (Anti-Human CD22 Recombinant Antibody) is a bispecific antibody that targets both HER2/neu and CD3. It functions by activating Fcγ type I/III receptors, which facilitates the formation of a tri-cell complex involving tumor cells, T cells, and accessory cells. This compound has been utilized in the research of breast cancer [1].Couleur et forme :LiquidTrosunilimab
Trosunilimab is a chimeric humanized antibody of the IgG1κ type targeting ITGA4_ITGB7, with HumanIgG1kappa, Isotype Control as its corresponding isotype control.Couleur et forme :Odour LiquidCyclo(Ala-Arg-Gly-Asp-Mamb)
CAS :Cyclo(Ala-Arg-Gly-Asp-Mamb) is a selective antagonist of the RGD peptide with potential applications in pulmonary arterial hypertension research [1].Formule :C23H32N8O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.55SMS 121
CAS :SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.Formule :C20H21NO5Degré de pureté :98.29%Couleur et forme :SoildMasse moléculaire :355.38Obrixtamig
Obrixtamig is a chimeric human antibody of the L-κ-G1-h-CH2-CH3_L-λ-G1-h-CH2-CH3 type, targeting CD3E/HEK.Couleur et forme :Odour LiquidVolociximab
CAS :Volociximab (M200) is an IgG4 monoclonal antibody targeting the α5β1 integrin , with antiangiogenic, antitumor and anticancer activity, inhibits the growth of rabbit VX2 tumors and is used to study solid tumors.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.4 kDaIndatuximab
Indatuximab is a chimeric antibody targeting CD13, used in the synthesis of ADC compound Indatuximab ravtansine.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :146.1 kDaGRGDSPK
CAS :GRGDSPK (EMD 56574) is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.Formule :C28H49N11O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.76C16Y
CAS :C16Y, a short peptide, serves as an inhibitor for the integrins αvβ3 and α5β1. It targets the cell membrane and exerts its antitumor activity by inhibiting angiogenesis.Formule :C78H115N17O17Couleur et forme :SolidMasse moléculaire :1562.85GSK 3008348 hydrochloride
CAS :GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Formule :C29H37N5O2xHClDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :0Azelaoyl PAF
CAS :Azelaoyl PAF is a potent PPARγ agonist that competitively binds thiazolidinediones.promotes the uptake of oxLDL by macrophages by upregulating CD36 expression.Formule :C33H66NO9PCouleur et forme :SolidMasse moléculaire :651.85Obtustatin triacetate
Obtustatin triacetate, a 41-residue non-RGD disintegrin isolated from the venom of Vipera lebetina obtusa, serves as a potent and selective inhibitor of theFormule :C184H284N52O57S8·3C2H4O2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :4573.21BT100
BT100, an aptamer, impedes the interaction of von Willebrand factor (VWF) with platelet glycoprotein GPIb, thus obstructing arterial thrombosis [1].Degré de pureté :98%Couleur et forme :Odour SolidRGD Trifluoroacetate
CAS :RGD Trifluoroacetate is a tripeptide for cell adhesion, effective on 24 integrins, and widely used for synthetic surface binding.Formule :C14H23F3N6O8Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :460.367Cilengitide TFA
CAS :Cilengitide, αvβ3/αvβ5 inhibitor, IC50: 4.1/79 nM in vitro. 10x selectivity vs. gpIIbIIIa. Phase 2.Formule :C29H41F3N8O9Couleur et forme :SolidMasse moléculaire :702.68DOTA-cyclo(RGDfK)
CAS :DOTA-cyclo(RGDfK) is a and DOTA-like chelator peptide,the αvβ3 integrin receptor ,radionuclide coupled compounds RDCs cancer diagnostics and therapy.Formule :C43H67N13O14Couleur et forme :SoildMasse moléculaire :990.07MK-0429
CAS :MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).Formule :C23H29N5O4Couleur et forme :SolidMasse moléculaire :439.51Anti-Mouse CD3 Antibody (17A2)
Anti-Mouse CD3 Antibody (17A2) is an IgG2b class antibody of murine origin targeting CD3 and can be used to study TCR signaling and antigen recognition.Degré de pureté :99%Couleur et forme :Odour LiquidGPRP
CAS :GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.Formule :C18H31N7O5Couleur et forme :White To Off-White PowderMasse moléculaire :425.48Lifitegrast sodium
CAS :Lifitegrast sodium (SAR-1118-023 sodium) is an integrin antagonist that reduces ocular surface inflammation and can be used to study dry eye.Formule :C29H23Cl2N2NaO7SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :637.46BIO-1211
CAS :BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8E7820
CAS :E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).Formule :C17H12N4O2SDegré de pureté :98.31% - 99.11%Couleur et forme :SolidMasse moléculaire :336.37Ref: TM-T4435
1mg34,00€2mg49,00€5mg65,00€1mL*10mM (DMSO)80,00€10mg84,00€25mg137,00€50mg200,00€100mg321,00€200mg477,00€GPRP acetate (67869-62-9 free base)
CAS :GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.
Formule :C20H35N7O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :485.53Natalizumab
CAS :Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Degré de pureté :97.15% (SDS-PAGE); 97.2% (SEC-HPLC) - 98.00%Couleur et forme :LiquidMasse moléculaire :146.19 kDaGRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Formule :C24H41N9O12Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :647.64Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.Formule :C19H34N8O11Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :550.52LXW7
CAS :LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (Formule :C29H48N12O12S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :820.89MNS
CAS :MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Formule :C9H7NO4Degré de pureté :98.53%Couleur et forme :Yellow PowderMasse moléculaire :193.16GLPG0187
CAS :GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).Formule :C29H37N7O5SDegré de pureté :99.4% - 99.70%Couleur et forme :SolidMasse moléculaire :595.71Ref: TM-T4259
1mg44,00€5mg98,00€1mL*10mM (DMSO)129,00€10mg144,00€25mg236,00€50mg350,00€100mg522,00€500mg1.134,00€Cyclo(-RGDfK) TFA
CAS :Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).Formule :C29H42F3N9O9Degré de pureté :98.99% - 99.54%Couleur et forme :SolidMasse moléculaire :717.69OSU-T315
CAS :OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.Formule :C30H30F3N5ODegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5485
1mg88,00€5mg187,00€1mL*10mM (DMSO)220,00€10mg298,00€25mg533,00€50mg755,00€100mg1.008,00€200mg1.359,00€A-205804
CAS :A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.Formule :C15H12N2OS2Degré de pureté :98.07% - 98.52%Couleur et forme :SolidMasse moléculaire :300.4Ref: TM-T2254
2mg42,00€5mg50,00€1mL*10mM (DMSO)67,00€10mg77,00€25mg152,00€50mg258,00€100mg505,00€500mg1.108,00€Arginine-glycine-aspartic acid
CAS :RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.Formule :C12H22N6O6Degré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :346.34TR-14035
CAS :TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).Formule :C24H21Cl2NO5Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.33Ref: TM-T5310
1mg50,00€5mg99,00€1mL*10mM (DMSO)102,00€10mg152,00€25mg245,00€50mg353,00€100mg492,00€200mg700,00€Cilengitide
CAS :Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66ILK-IN-2
CAS :ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59Ref: TM-T5488
1mg46,00€5mg92,00€10mg122,00€1mL*10mM (DMSO)130,00€25mg154,00€50mg182,00€100mg266,00€200mg386,00€Lifitegrast
CAS :Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
Formule :C29H24Cl2N2O7SDegré de pureté :99.39% - 99.66%Couleur et forme :SolidMasse moléculaire :615.48Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.1% - 99.93%Couleur et forme :SolidMasse moléculaire :558.70ILK-IN-3
CAS :ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formule :C10H12N6ODegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :232.24iRGD peptide
CAS :iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.Formule :C35H57N13O14S2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :948.04roxifiban
CAS :Roxifiban, a prodrug of XV459, is an antiplatelet agent with high affinity and specificity for platelet glycoprotein IIb/IIIa complex(GPIIb/IIIa) receptors.
Formule :C21H29N5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.48Hexapeptide-10 Acetate
Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.Formule :C30H57N7O10Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :675.81Emvistegrast
CAS :Emvistegrast is a quinolone derivative that acts as an antagonist for the α4β7 integrin.Formule :C35H32F4N6O6Couleur et forme :SolidMasse moléculaire :708.66Carotegrast methyl
CAS :Carotegrast methyl (AJM300), an orally-active small molecule, can antagonize the α4 integrin receptor. It is a specific and dual α4β1/α4β7 integrin antagonist.Formule :C28H26Cl2N4O5Degré de pureté :99.26% - 99.72%Couleur et forme :SolidMasse moléculaire :569.44HSDVHK-NH2 acetate
P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).Formule :C32H52N12O11Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :780.39Arg-Gly-Asp TFA (99896-85-2(free base))
Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.Formule :C14H23F3N6O8Degré de pureté :99.2% - ≥98%Couleur et forme :SolidMasse moléculaire :460.36Irigenin
CAS :Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31Cyclo(RADfK)
CAS :Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.Formule :C28H43N9O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :617.7Orbofiban
CAS :Orbofiban, an orally administered antagonist of the platelet GPIIb/IIIa receptor, effectively inhibits platelet aggregation.Formule :C17H23N5O4Couleur et forme :SolidMasse moléculaire :361.4A-286982
CAS :A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Formule :C24H27N3O4SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :453.55Ref: TM-T21781
1mg34,00€2mg48,00€5mg71,00€1mL*10mM (DMSO)77,00€10mg102,00€25mg200,00€50mg333,00€100mg495,00€PND-1186
CAS :PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5Carotegrast methyl HCl
CAS :Carotegrast methyl (AJM300/PTC-100) is an oral α4 integrin blocker reducing inflammation and experimental colitis.Formule :C25H20Cl3N3O5Couleur et forme :SolidMasse moléculaire :548.801Eptifibatide acetate (148031-34-9 free base)
CAS :Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.Formule :C35H49N11O9S2·xC2H4O2Degré de pureté :99.7% - 99.87%Couleur et forme :SolidMasse moléculaire :891.01Tirofiban hydrochloride monohydrate
CAS :Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.Formule :C22H39ClN2O6SDegré de pureté :98.81% - >99.99%Couleur et forme :White SolidMasse moléculaire :495.07Leukadherin-1
CAS :Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.Formule :C22H15NO4S2Degré de pureté :98.49% - 98.93%Couleur et forme :SolidMasse moléculaire :421.49CWHM-12
CAS :CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).Formule :C26H32BrN5O6Degré de pureté :98.05% - 99.83%Couleur et forme :SolidMasse moléculaire :590.47Ref: TM-TQ0250
1mg40,00€2mg52,00€5mg88,00€1mL*10mM (DMSO)96,00€10mg126,00€25mg221,00€50mg369,00€100mg550,00€Cyclo(RGDyK) trifluoroacetate
CAS :Cyclo(RGDyK) trifluoroacetate is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.Formule :C31H43F6N9O12Degré de pureté :95.28% - ≥95%Couleur et forme :SolidMasse moléculaire :847.72α2β1 Integrin Ligand Peptide acetate
α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.Formule :C16H26N4O11Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :450.4Pyrintegrin
CAS :Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.Formule :C23H25N5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :451.54Ref: TM-T16695
1mg78,00€2mg90,00€5mg150,00€1mL*10mM (DMSO)165,00€10mg215,00€25mg385,00€50mg595,00€100mg858,00€Cyclo(-RGDfK)
CAS :Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.Formule :C27H41N9O7Degré de pureté :95.29% - >99.99%Couleur et forme :SolidMasse moléculaire :603.67H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS :RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.Formule :C23H38N10O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :614.61Arg-Gly-Asp-Ser
CAS :Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.Formule :C15H27N7O8Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :433.42RO0270608
CAS :RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.Formule :C24H19Cl3N2O4Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :505.78Bexotegrast
CAS :Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).Formule :C27H36N6O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :492.61Vepsitamab
CAS :Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.Couleur et forme :LiquidVixtimotamab
Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively engages human CD33 and CD3 antigens.Couleur et forme :Odour LiquidGresonitamab
CAS :Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.Couleur et forme :LiquidPavurutamab
CAS :Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.Couleur et forme :LiquidAnti-Mouse CD32/CD16 Antibody (2.4G2)
Anti-Mouse CD32/CD16 Antibody is a rat-derived IgG2b inhibitor targeting the mouse CD32/CD16 antigens.Couleur et forme :Odour LiquidMasse moléculaire :150 kDaVoxalatamab
CAS :Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].Couleur et forme :LiquidUbamatamab
CAS :Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].Degré de pureté :95%Couleur et forme :LiquidTepoditamab
CAS :Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.Couleur et forme :LiquidFlotetuzumab
CAS :Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.Couleur et forme :LiquidAcapatamab
CAS :Acapatamab (AMG-160) is a Half-Life Extended (HLE) Bispecific T-cell Engager (BiTE) with domains that bind to PSMA and CD3. It exhibits Kd values of 14.8 nM for hPSMA and 22.4 nM for hCD3. This compound is utilized in cancer research.Couleur et forme :LiquidVatelizumab
CAS :Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :~150 kDaObrindatamab
CAS :Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.Couleur et forme :LiquidAnti-Mouse TCR γ/δ Antibody (UC7-13D5)
Anti-Mouse TCR gamma/delta Antibody is a host Armenian Hamster-derived IgG class inhibitor targeting the mouse TCR gamma/delta receptor.Couleur et forme :Odour LiquidVibecotamab
CAS :Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.Couleur et forme :LiquidAnti-Mouse CD3ε Antibody (145-2C11)
Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activationDegré de pureté :99%Couleur et forme :Odour LiquidMasse moléculaire :150 kDaVonsetamig
CAS :Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Couleur et forme :LiquidRovelizumab
CAS :Rovelizumab, Humanized anti-CD11/CD18 mAb, inhibits overactive leukocytes during shock, for MS, hemorrhagic shock, myocardial infarction, and stroke.Degré de pureté :95% - 95%Couleur et forme :LiquidEnlimomab
CAS :Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.Couleur et forme :LiquidAlnuctamab
CAS :Alnuctamab (EM901) is a humanized, asymmetric two-arm IgG T-cell engager (TCE) with potential applications in immunological research [1].Couleur et forme :LiquidPacanalotamab
CAS :Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.Couleur et forme :Liquid
