Microtubules associés
Les inhibiteurs des protéines associées aux microtubules ciblent les protéines qui interagissent avec les microtubules, les composants structurels du cytosquelette de la cellule qui sont essentiels à la division cellulaire. Ces protéines régulent la stabilité et la dynamique des microtubules pendant la mitose. L'inhibition des protéines associées aux microtubules peut perturber la fonction des microtubules, entraînant un arrêt du cycle cellulaire et l'apoptose, en particulier dans les cellules cancéreuses à division rapide. Ces inhibiteurs sont largement utilisés dans la recherche sur le cancer et le développement de médicaments. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de protéines associées aux microtubules de haute qualité pour soutenir vos recherches sur la division cellulaire, la dynamique du cytosquelette et la thérapie contre le cancer.
283 produits trouvés pour "Microtubules associés".
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Microtubule inhibitor 11
Microtubule inhibitor 11 (compound 33) is a tubulin inhibitor with a mechanism of action similar to that of colchicine. It is utilized in cancer-related research.Formule :C28H27N3O4Couleur et forme :SolidMasse moléculaire :469.20016Tubulin polymerization-IN-44
Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making itFormule :C19H15Cl2N3O3SCouleur et forme :SolidMasse moléculaire :436.31Microtubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.117-Epi-docetaxel
CAS :7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.Formule :C43H53NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :807.8810-Oxo Docetaxel
CAS :10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.8742-Methylthiophenothiazine
CAS :2-Methylthiophenothiazine, with CAS No. 7643-08-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Methylthiophenothiazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C13H11NS2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :245.36Katanin-IN-1
Katanin-IN-1 (122589735) is an effective inhibitor of katanin, and it holds potential for cancer research.Formule :C24H33N9O3Couleur et forme :SolidMasse moléculaire :495.58Vinflunine Tartrate
CAS :Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formule :C45H54F2N4O8·xC4H6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :967.02Ref: TM-T6722
2mgÀ demander5mgÀ demander10mgÀ demander25mgÀ demander50mgÀ demander1mL*10mM (DMSO)À demanderPYRIB-SO 2
PYRIB-SO 2 is an effective antimitotic (mitotic) agent that exhibits antiproliferative activity and induces cell cycle arrest at the G2/M phase. It disrupts and reduces microtubule structures by binding to the colchicine-binding site (C-BS) on α, β-tubulin.Formule :C14H12ClN3O4SCouleur et forme :SolidMasse moléculaire :353.0237Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cellFormule :C24H20FN3O3Couleur et forme :SolidMasse moléculaire :417.43Phomopsinamine
CAS :Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Formule :C32H43ClN6O8Couleur et forme :SolidMasse moléculaire :675.17Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFormule :C17H13ClN6OSCouleur et forme :SolidMasse moléculaire :384.84Epothilone F
CAS :Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68Tubulin inhibitor 24
CAS :Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formule :C22H21N3O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :375.42Sudocetaxel
CAS :Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.Formule :C48H59NO16Couleur et forme :SolidMasse moléculaire :905.98Microtubule destabilizing agent-1
CAS :Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Formule :C22H26N4O4Couleur et forme :SolidMasse moléculaire :410.47Combretastatin A-1 phosphate tetrasodium
CAS :OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Formule :C18H18Na4O12P2Couleur et forme :SolidMasse moléculaire :580.24Pironetin
CAS :Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45Monomethyl auristatin E intermediate-8
MonomethylauristatinE intermediate-8 is an intermediate compound in the synthesis of MonomethylauristatinE. MonomethylauristatinE (MMAE) acts as a microtubule/tubulin inhibitor with anticancer properties. It is widely utilized as the cytotoxic component in antibody-drug conjugates (ADCs).Formule :C20H31NO5Couleur et forme :SolidMasse moléculaire :365.220227-Epi-10-oxo-docetaxel
CAS :7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.86
