Microtubules associés
Les inhibiteurs des protéines associées aux microtubules ciblent les protéines qui interagissent avec les microtubules, les composants structurels du cytosquelette de la cellule qui sont essentiels à la division cellulaire. Ces protéines régulent la stabilité et la dynamique des microtubules pendant la mitose. L'inhibition des protéines associées aux microtubules peut perturber la fonction des microtubules, entraînant un arrêt du cycle cellulaire et l'apoptose, en particulier dans les cellules cancéreuses à division rapide. Ces inhibiteurs sont largement utilisés dans la recherche sur le cancer et le développement de médicaments. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de protéines associées aux microtubules de haute qualité pour soutenir vos recherches sur la division cellulaire, la dynamique du cytosquelette et la thérapie contre le cancer.
286 produits trouvés pour "Microtubules associés".
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Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Couleur et forme :Odour SolidCys-McMMAF
CAS :Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.Formule :C52H83N7O13SCouleur et forme :SolidMasse moléculaire :1046.32Vinflunine Tartrate
CAS :Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Formule :C45H54F2N4O8·xC4H6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :967.02Ref: TM-T6722
2mgÀ demander5mgÀ demander10mgÀ demander25mgÀ demander50mgÀ demander1mL*10mM (DMSO)À demander10-Oxo Docetaxel
CAS :10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.8742-Methylthiophenothiazine
CAS :2-Methylthiophenothiazine, with CAS No. 7643-08-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Methylthiophenothiazine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C13H11NS2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :245.36Katanin-IN-1
Katanin-IN-1 (122589735) is an effective inhibitor of katanin, and it holds potential for cancer research.Formule :C24H33N9O3Couleur et forme :SolidMasse moléculaire :495.58PYRIB-SO 2
PYRIB-SO 2 is an effective antimitotic (mitotic) agent that exhibits antiproliferative activity and induces cell cycle arrest at the G2/M phase. It disrupts and reduces microtubule structures by binding to the colchicine-binding site (C-BS) on α, β-tubulin.Formule :C14H12ClN3O4SCouleur et forme :SolidMasse moléculaire :353.0237T-808
CAS :T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.Formule :C17H19FN4Couleur et forme :SolidMasse moléculaire :298.36(2S,3R)-Dap-NE hydrochloride
(2S,3R)-Dap-NE hydrochloride is an amino acid residue of the pentapeptide Dolastatin 10. Dolastatin 10 inhibits tubulin polymerization and mitosis, exhibiting anticancer properties.Formule :C18H29ClN2O3Couleur et forme :SolidMasse moléculaire :356.18667Microtubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.11KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structureFormule :C24H21NO5Couleur et forme :SolidMasse moléculaire :403.43Diminutol
CAS :Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Formule :C19H26N6OSCouleur et forme :SolidMasse moléculaire :386.51Anti-α-Tubulin Antibody, AF555 conjugate
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for theCouleur et forme :SolidPironetin
CAS :Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45E7130
E7130 is a microtubule inhibitor that enhances the tumor microenvironment by inhibiting cancer-associated fibroblasts and facilitating the remodeling of the tumor vasculature system.Formule :C58H83NO17Couleur et forme :SolidMasse moléculaire :1065.5661Sudocetaxel
CAS :Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.Formule :C48H59NO16Couleur et forme :SolidMasse moléculaire :905.98Monomethyl auristatin E intermediate-8
MonomethylauristatinE intermediate-8 is an intermediate compound in the synthesis of MonomethylauristatinE. MonomethylauristatinE (MMAE) acts as a microtubule/tubulin inhibitor with anticancer properties. It is widely utilized as the cytotoxic component in antibody-drug conjugates (ADCs).Formule :C20H31NO5Couleur et forme :SolidMasse moléculaire :365.22022Epothilone F
CAS :Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68Phomopsinamine
CAS :Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Formule :C32H43ClN6O8Couleur et forme :SolidMasse moléculaire :675.17Tubulin inhibitor 24
CAS :Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Formule :C22H21N3O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :375.42
