Chromatine/Épigénétique
Les inhibiteurs de la chromatine/épigénétique sont des composés qui modulent la structure et la fonction de la chromatine ou interfèrent avec les modifications épigénétiques, telles que la méthylation de l'ADN et la modification des histones. Ces inhibiteurs sont des outils essentiels pour étudier la régulation de l'expression génique et le rôle de l'épigénétique dans des maladies telles que le cancer, les troubles neurologiques et les anomalies du développement. En ciblant les processus épigénétiques, ces inhibiteurs peuvent modifier les schémas d'expression génique et offrir de nouvelles perspectives thérapeutiques. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de la chromatine/épigénétique de haute qualité pour soutenir vos recherches en biologie moléculaire, génétique et épigénétique.
Sous-catégories appartenant à la catégorie "Chromatine/Épigénétique"
2235 produits trouvés pour "Chromatine/Épigénétique"
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PF-9363
CAS :<p>PF-9363 (CTX-3648) is a potent and high selective KAT6A/KAT6B inhibitor. PF-9363 can be used for the research of cancer.</p>Formule :C20H20N4O6SDegré de pureté :99.03% - 99.7%Couleur et forme :SolidMasse moléculaire :444.46UNC1999
CAS :<p>UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).</p>Formule :C33H43N7O2Degré de pureté :99.19% - >99.99%Couleur et forme :SolidMasse moléculaire :569.74Deoxyshikonin
CAS :<p>1.</p>Formule :C16H16O4Degré de pureté :99.36% - ≥95%Couleur et forme :SolidMasse moléculaire :272.31,2-Dipalmitoyl-sn-glycerol
CAS :<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Formule :C35H68O5Degré de pureté :97.84% - 99.78%Couleur et forme :SolidMasse moléculaire :568.91Atractylenolide I
CAS :<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Formule :C15H18O2Degré de pureté :97.55% - 99.92%Couleur et forme :SolidMasse moléculaire :230.38-CHLOROQUINAZOLIN-4(1H)-ONE
CAS :<p>8-CHLOROQUINAZOLIN-4(1H)-ONE is inhibitor of Poly [ADP-ribose] polymerase 1 (human)</p>Formule :C8H5ClN2ODegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :180.59ICG001
CAS :<p>ICG001 antagonizes Wnt signaling, binds CBP with 3 μM IC50, not p300.</p>Formule :C33H32N4O4Degré de pureté :99.06% - 99.95%Couleur et forme :SolidMasse moléculaire :548.63(R)-(-)-JQ1 Enantiomer
CAS :<p>(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)</p>Formule :C23H25ClN4O2SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :456.99MI-463
CAS :<p>MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).</p>Formule :C24H23F3N6SDegré de pureté :99.18% - >99.99%Couleur et forme :SolidMasse moléculaire :484.54Fucosterol
CAS :<p>Fucosterol, from E. stolonifera, has anti-diabetic, anti-adipogenic, anti-cancer properties; it affects PPARα and C/EBPα to control fat cell formation.</p>Formule :C29H48ODegré de pureté :98.39% - 99.68%Couleur et forme :White PowderMasse moléculaire :412.69KC7F2
CAS :<p>KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity.</p>Formule :C16H16Cl4N2O4S4Degré de pureté :98% - 99.11%Couleur et forme :SolidMasse moléculaire :570.38JQEZ5
CAS :<p>JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).</p>Formule :C30H38N8O2Degré de pureté :98.14% - ≥98%Couleur et forme :SolidMasse moléculaire :542.68SGC707
CAS :<p>SGC707 is a potent, selective, and cell-active allosteric inhibitor of PRMT3.</p>Formule :C16H18N4O2Degré de pureté :98.45% - 99.79%Couleur et forme :SolidMasse moléculaire :298.34BI-7273
CAS :<p>BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.</p>Formule :C20H23N3O3Degré de pureté :97.37% - 99.57%Couleur et forme :SolidMasse moléculaire :353.41Rucaparib hydrochloride
CAS :<p>Rucaparib hydrochloride (AG014699) is an oral PARP inhibitor with Ki 1.4 nM for PARP1 and hinders H6PD, studied in CRPC research.</p>Formule :C19H19ClFN3OCouleur et forme :SolidMasse moléculaire :359.83XMD8-92
CAS :<p>XMD8-92 is an effective and specific BMK1/ERK5 inhibitor (Kd: 80 nM).</p>Formule :C26H30N6O3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :474.55Rucaparib acetate
CAS :<p>Rucaparib acetate, an oral PARP-1, -2, -3 inhibitor (Ki 1.4 nM for PARP1), also moderately inhibits H6PD; promising for CRPC research.</p>Formule :C21H22FN3O3Couleur et forme :SolidMasse moléculaire :383.423GSK-LSD1 dihydrochloride
CAS :<p>GSK-LSD1 dihydrochloride: potent LSD1 inhibitor, >1000x selective over MAO-A/B, LSD2, IC50: 16 nM.</p>Formule :C14H22Cl2N2Degré de pureté :98.72% - >99.99%Couleur et forme :SolidMasse moléculaire :289.24NVP-TNKS656
CAS :<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Formule :C27H34N4O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :494.58Menin-MLL inhibitor 20
CAS :<p>Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.</p>Formule :C33H40N8O4Degré de pureté :97.77%Couleur et forme :SolidMasse moléculaire :612.72TCS PIM-1 1
CAS :<p>TCS PIM-1 1 (SC 204330) is a potent ATP-competitive inhibitor of Pim-1 kinase with an IC50 of 50 nM, selective over MEK1/2 and Pim-2.</p>Formule :C18H11BrN2O2Degré de pureté :97% - 97.98%Couleur et forme :SolidMasse moléculaire :367.2MI-538
CAS :<p>MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).</p>Formule :C27H25F3N8OSDegré de pureté :99.61% - 99.8%Couleur et forme :SolidMasse moléculaire :566.6RBN012759
CAS :<p>RBN012759 inhibits PARP14 protein and is more than 300-fold selective over all PARP family members.Cost-effective and quality-assured.</p>Formule :C19H23FN2O3SDegré de pureté :98.87% - 99.96%Couleur et forme :SolidMasse moléculaire :378.46GLPG0634 analog
CAS :<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Formule :C23H18N6O2Degré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :410.43Ethyl 3,4-dihydroxybenzoate
CAS :<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.17Ruboxistaurin
CAS :<p>Ruboxistaurin (LY333531) is a selective PKC beta inhibitor, Ki 2 nM, inhibits beta I/II (IC50: 4.7/5.9 nM), orally active.</p>Formule :C28H28N4O3Couleur et forme :SolidMasse moléculaire :468.55DMOG
CAS :<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Formule :C6H9NO5Degré de pureté :80.23% - 99.98%Couleur et forme :SolidMasse moléculaire :175.14EB-47 dihydrochloride
CAS :<p>EB 47 is an effective inhibitor of PARP-1 (IC50: 45 nM).</p>Formule :C24H29Cl2N9O6Couleur et forme :SolidMasse moléculaire :610.45SC-43
CAS :<p>SC-43 is a potent and orally active agonist of SHP-1 (PTPN6).</p>Formule :C21H13ClF3N3O2Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :431.8Ritlecitinib tosylate
CAS :<p>Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.</p>Formule :C22H27N5O4SCouleur et forme :SolidMasse moléculaire :457.549Amodiaquine
CAS :<p>Amodiaquine is a synthetic aminoquinoline, used to treat malaria.</p>Formule :C20H22ClN3ODegré de pureté :99.78% - 99.99%Couleur et forme :Crystals From Absolute Ethanol SolidMasse moléculaire :355.86MR837
CAS :<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Formule :C16H14N2OSDegré de pureté :99.77% - 99.85%Couleur et forme :SolidMasse moléculaire :282.36Pinometostat
CAS :<p>Pinometostat (EPZ-5676) is a potent DOT1L histone methyltransferase inhibitor. Pinometostat has antitumor activity. Cost effective and quality assured.</p>Formule :C30H42N8O3Degré de pureté :99.19% - 99.86%Couleur et forme :SolidMasse moléculaire :562.71MS31 trihydrochloride
<p>MS31 trihydrochloride: a selective SPIN1 inhibitor, binds H3K4me3 (IC50: 77-243 nM), non-toxic to healthy cells.</p>Formule :C20H30Cl3N3O2Couleur et forme :SolidMasse moléculaire :450.83Anacardic Acid
CAS :<p>Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases.</p>Formule :C22H36O3Degré de pureté :97.47% - 99.87%Couleur et forme :SolidMasse moléculaire :348.525,7,4'-Trimethoxyflavone
CAS :<p>5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.</p>Formule :C18H16O5Degré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :312.32PF-CBP1 hydrochloride
CAS :<p>PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).</p>Formule :C29H37ClN4O3Degré de pureté :97.11% - 99.02%Couleur et forme :SolidMasse moléculaire :525.08MK-8617
CAS :<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Formule :C24H21N5O4Degré de pureté :99.38% - >99.99%Couleur et forme :SolidMasse moléculaire :443.45Abrocitinib
CAS :<p>Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).</p>Formule :C14H21N5O2SDegré de pureté :99.09% - 99.91%Couleur et forme :SolidMasse moléculaire :323.41C-7280948
CAS :<p>C-7280948 is a PRMT1 inhibitor.</p>Formule :C14H16N2O2SDegré de pureté :99.55% - ≥95%Couleur et forme :SolidMasse moléculaire :276.35Daphnetin
CAS :<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Formule :C9H6O4Degré de pureté :97.47% - 99.8%Couleur et forme :SolidMasse moléculaire :178.14B2
CAS :<p>B2 (Linazolamide intermediate B impurity 2) promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease</p>Formule :C20H17ClN4O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :396.83XAV-939
CAS :<p>XAV-939 (NVP-XAV939) shows the selective inhibition against Wnt/β-catenin-mediated transcription by tankyrase1/2 inhibition (IC50: 11/4 nM in cell-free assay).</p>Formule :C14H11F3N2OSDegré de pureté :97.47% - 99.67%Couleur et forme :SolidMasse moléculaire :312.31AZD1208
CAS :<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Formule :C21H21N3O2SDegré de pureté :97.24% - 99.83%Couleur et forme :SolidMasse moléculaire :379.48dBET6
CAS :<p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>Formule :C42H45ClN8O7SDegré de pureté :97.57% - 99.12%Couleur et forme :SolidMasse moléculaire :841.37Niraparib hydrochloride
CAS :<p>Niraparib hydrochloride (MK-4827) is a PARP inhibitor with potential cancer treatment effects, causing DNA damage and apoptosis.</p>Formule :C19H21ClN4ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :356.85Birabresib
CAS :<p>Birabresib (MK-8628) is a synthetic, small molecule inhibitor of the BET (Bromodomain and Extra-Terminal) family of bromodomain-containing proteins 2, 3 and 4</p>Formule :C25H22ClN5O2SDegré de pureté :98.3% - 99.36%Couleur et forme :SolidMasse moléculaire :491.99Rucaparib Phosphate
CAS :<p>Rucaparib Phosphate (PF-01367338 phosphate) is an inhibitor of PARP that is used in clinical therapy to sensitize cancer cells to chemotherapy.</p>Formule :C19H18FN3O·H3PO4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :421.363-methyl-1,2,3,4-tetrahydroquinazolin-2-one
CAS :<p>3-methyl-1,2,3,4-tetrahydroquinazolin-2-one is a inhibitor of BRD4 .</p>Formule :C9H10N2ODegré de pureté :99.3% - 99.64%Couleur et forme :SolidMasse moléculaire :162.19SHR0302
CAS :<p>SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,</p>Formule :C18H22N8O2SDegré de pureté :99.11%Couleur et forme :SolidMasse moléculaire :414.48MI-503
CAS :<p>MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.</p>Formule :C28H27F3N8SDegré de pureté :99.87% - 99.99%Couleur et forme :SolidMasse moléculaire :564.63Tubacin
CAS :<p>Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.</p>Formule :C41H43N3O7SDegré de pureté :97.62% - 98.75%Couleur et forme :SolidMasse moléculaire :721.86SETDB1-TTD-IN-1 TFA
<p>SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.</p>Formule :C30H32F3N5O4Couleur et forme :SolidMasse moléculaire :583.6BYK204165
CAS :<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Formule :C15H12N2O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :252.27J-147
CAS :<p>J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.</p>Formule :C18H17F3N2O2Degré de pureté :99.61% - >99.99%Couleur et forme :SolidMasse moléculaire :350.33Alobresib
CAS :<p>Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.</p>Formule :C26H23N5O2Degré de pureté :97.63%Couleur et forme :SolidMasse moléculaire :437.495-AIQ
CAS :<p>5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.</p>Formule :C9H8N2ODegré de pureté :95.95%Couleur et forme :SolidMasse moléculaire :160.17BAZ1A-IN-1
CAS :<p>BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.</p>Formule :C16H12N4O3SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :340.36Ruxolitinib (S enantiomer)
CAS :<p>Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.</p>Formule :C17H18N6Degré de pureté :99.37% - 99.79%Couleur et forme :SolidMasse moléculaire :306.36ML367
CAS :<p>ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.</p>Formule :C19H12F2N4Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :334.32I-CBP112
CAS :<p>I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.</p>Formule :C27H36N2O5Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :468.59CPI-455
CAS :<p>CPI-455 is a specific KDM5 inhibitor.</p>Formule :C16H14N4ODegré de pureté :97.87% - 99.03%Couleur et forme :SolidMasse moléculaire :278.31Momelotinib HCl
CAS :<p>Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.</p>Formule :C23H24Cl2N6O2Couleur et forme :SolidMasse moléculaire :487.38BCI-121
CAS :<p>BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.</p>Formule :C14H18BrN3O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :340.22SGC2085 HCl
CAS :<p>SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.</p>Formule :C19H24N2O2·HClDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :348.87Splitomicin
CAS :<p>Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a</p>Formule :C13H10O2Degré de pureté :97.09% - 99.11%Couleur et forme :SolidMasse moléculaire :198.224-Phenylbutyric acid
CAS :<p>4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.</p>Formule :C10H12O2Degré de pureté :98.40% - 99.76%Couleur et forme :SolidMasse moléculaire :164.2Gandotinib
CAS :<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Formule :C23H25ClFN7ODegré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :469.94Protein kinase inhibitor 6
CAS :<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Formule :C13H9FN2SDegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :244.29Iso-H7 dihydrochloride
CAS :<p>Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.</p>Formule :C14H19Cl2N3O2SDegré de pureté :99.53%Couleur et forme :White Crystalline SolidMasse moléculaire :364.29dencichine
CAS :<p>Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.</p>Formule :C5H8N2O5Degré de pureté :99.93% - ≥95%Couleur et forme :SolidMasse moléculaire :176.13Cerdulatinib
CAS :<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Formule :C20H27N7O3SDegré de pureté :98.74% - 99.49%Couleur et forme :SolidMasse moléculaire :445.543-TYP
CAS :<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Formule :C7H6N4Degré de pureté :99.16% - >99.99%Couleur et forme :SolidMasse moléculaire :146.15Nudifloramide
CAS :<p>Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).</p>Formule :C7H8N2O2Degré de pureté :99.7% - ≥95%Couleur et forme :SolidMasse moléculaire :152.15M1001
CAS :<p>M1001 is a HIF-2α agonist.</p>Formule :C17H17N3O2SDegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :327.4Mivebresib
CAS :<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Formule :C22H19F2N3O4SDegré de pureté :98.74% - 99.32%Couleur et forme :SolidMasse moléculaire :459.47GSK467
CAS :<p>GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).</p>Formule :C17H13N5O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :319.32MG 149
CAS :<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Formule :C22H28O3Degré de pureté :98.69% - 99.86%Couleur et forme :SolidMasse moléculaire :340.46Amifostine trihydrate
CAS :<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Formule :C5H15N2O3PS·3H2ODegré de pureté :99.71% - 99.80%Couleur et forme :SolidMasse moléculaire :268.27Tofacitinib Citrate
CAS :<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formule :C22H28N6O8Degré de pureté :99.19% - 99.75%Couleur et forme :SolidMasse moléculaire :504.49DDP-38003 trihydrochloride
<p>DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.</p>Formule :C21H29Cl3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.84WHI-P154
CAS :<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formule :C16H14BrN3O3Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :376.2Selisistat
CAS :<p>Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).</p>Formule :C13H13ClN2ODegré de pureté :98.53% - 99.94%Couleur et forme :SolidMasse moléculaire :248.71Fedratinib
CAS :<p>Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.</p>Formule :C27H36N6O3SDegré de pureté :97.31% - 99.96%Couleur et forme :SolidMasse moléculaire :524.68BI 2536
CAS :<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Formule :C28H39N7O3Degré de pureté :98% - 99.88%Couleur et forme :SolidMasse moléculaire :521.65(+)-JQ-1
CAS :<p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>Formule :C23H25ClN4O2SDegré de pureté :97.57% - ≥95%Couleur et forme :SolidMasse moléculaire :456.99Niraparib tosylate
CAS :<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Formule :C19H20N4O·C7H8O3SDegré de pureté :99.34% - 99.87%Couleur et forme :SolidMasse moléculaire :492.59AZD-2461
CAS :<p>AZD2461 is a novel PARP inhibitor.</p>Formule :C22H22FN3O3Degré de pureté :98% - 99.87%Couleur et forme :SolidMasse moléculaire :395.43Acetyl Pentapeptide-1 acetate
<p>Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.</p>Formule :C34H55N9O12Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :781.86Bobcat339
CAS :<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Formule :C16H12ClN3ODegré de pureté :97.79% - 99.24%Couleur et forme :SolidMasse moléculaire :297.74Methyl L-histidinate dihydrochloride
CAS :<p>The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat</p>Formule :C7H13Cl2N3O2Degré de pureté :99.74%Couleur et forme :White To Off-White PowderMasse moléculaire :242.1A-196
CAS :<p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>Formule :C18H16Cl2N4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :359.25PFI-1
CAS :<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Formule :C16H17N3O4SDegré de pureté :98.74% - 99.19%Couleur et forme :SolidMasse moléculaire :347.39Isoxazole
CAS :<p>Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.</p>Formule :C3H3NODegré de pureté :99.34%Couleur et forme :Colorless LiquidMasse moléculaire :69.06Baricitinib phosphate
CAS :<p>Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.</p>Formule :C16H20N7O6PSDegré de pureté :99.4% - 99.82%Couleur et forme :SolidMasse moléculaire :469.41Aurora kinase inhibitor-2
CAS :<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Formule :C23H20N4O3Degré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :400.435-Ph-IAA
CAS :<p>5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.</p>Formule :C16H13NO2Degré de pureté :99.37% - 99.973%Couleur et forme :SolidMasse moléculaire :251.28WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Formule :C16H14Br2ClN3O3Degré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :491.56Hesperadin
CAS :<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Formule :C29H32N4O3SDegré de pureté :98.04% - 99.44%Couleur et forme :SolidMasse moléculaire :516.652-hexyl-4-Pentynoic Acid
CAS :<p>2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.</p>Formule :C11H18O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :182.26
